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5103-EDC tables
Course: ENHS 5103, Fall 2008School: Minnesota
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organohalogens Persistent Benzenehexachloride (BHC) 1,2-dibromoethane Chloroform Dioxins and furans Octachlorostyrene PBBs PCBs PCB, hydroxylated PBDEs Pentachlorophenol Food Antioxidant Butylated hydroxyanisole (BHA) Pesticides Acetochlor Alachlor Aldrin Allethrin, d-trans Amitrol Atrazine Carbaryl Chlofentezine Chlordane Cypermethrin DDT DDT Metabolite, p,p'-DDE Dicofol (Kelthane) Dieldrin Endosulfan Ethylene...
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organohalogens Persistent Benzenehexachloride (BHC) 1,2-dibromoethane Chloroform Dioxins and furans Octachlorostyrene PBBs PCBs PCB, hydroxylated PBDEs Pentachlorophenol Food Antioxidant Butylated hydroxyanisole (BHA) Pesticides Acetochlor Alachlor Aldrin Allethrin, d-trans Amitrol Atrazine Carbaryl Chlofentezine Chlordane Cypermethrin DDT DDT Metabolite, p,p'-DDE Dicofol (Kelthane) Dieldrin Endosulfan Ethylene thiourea Fenarimol Fenbuconazole Fenitrothion Fenvalerate Fipronil Heptachlor Heptachlor-epoxide Iprodione Karate Kepone (Chlordecone) Ketoconazole Lindane (Hexachlorocyclohexane) Linuron Malathion
Mancozeb Maneb Methomyl Methoxychlor Metribuzin Mirex Nitrofen Nonachlor, transOxychlordane Pendimethalin Pentachloronitrobenzene Permethrin Procymidone Prodiamine Pyrimethanil Sumithrin Tarstar Thiazopyr Thiram Toxaphene Triadimefon Triadimenol Tributyltin Trifluralin Vinclozolin Zineb Ziram Phthalates Butyl benzyl phthalate (BBP) Di-n-butyl phthalate (DBP) Di-ethylhexyl phthalate (DEHP) Diethyl Phthalate (DEP) Other Compounds Benzophenone Bisphenol A Bisphenol F Benzo(a)pyrene Carbendazim Ethane Dimethane Sulphonate Perfluorooctane sulfonate (PFOS) Nonylphenol, octylphenol Resorcinol Styrene dimers and trimers Metals
Arsenic Cadmium Lead Mercury
Persistent organohalogens Compound(s) Hormone system affected Mechanism if known
Benzenehexachloride (BHC) Thyroid 1,2-dibromoethane Reproductive Chloroform Reproductive Dioxins and furans (in order of antiestrogenicEstrogen : 2,3,7,8-tetrachlorodibenzo-p-dioxin > 2,3,7,8-tetrachlorodibenzofuran > potency work as anti-estrogen through binding with Ah receptor, which then inhibits estrogen receptor binding to estrogen response elements, thereby inhibiting estrogen action Octachlorostyrene Thyroid PBBs Estrogen/ Thyroid PCBs (in order of antiestrogenic Estrogen/androgen/Thyroid Inhibits estrogen binding potency: 3,3' -pentachlorobiphenyl , Adverse outcomes in to the receptor; works as > 3,3,4,4,5,5'-hexachlorobiphenyl reproductive systems. anti-estrogen. anti3,3',4,4-tetrachlorobiphenyl > androgenic via Ah 2,3,3',4,4',5'-hexa, 2,3,3',4,4'- and receptor interaction 2,3,4,4',5-pentachlorobiphenyl > Aroclors 1221, 1232. 1248, 1254, and 1260 were inactive as antiestrogens at the highest concentrations used in this study (10-6 Ni)
PCB, hydroxylated
Thyroid
Binds to thyroid hormone binding protein, but not to the thyroid hormone receptor. Interfere with thyroxine (T4) binding with transthryetin Reduces thyroid hormone possibly through a direct effect on the thyroid gland.
PBDEs Pentachlorophenol
Thyroid Thyroid
Food Antioxidant Compound Butylated hydroxyanisole (BHA) Hormone system affected Estrogen Mechanism Inhibits binding to the estrogen receptor.
Pesticides
Compound Acetochlor Alachlor Aldrin Allethrin, d-trans Amitrol
Hormone system affected Thyroid (decrease of thyroid hormone levels, increase in TSH) Thyroid (decrease of thyroid hormone levels, increase in TSH) Estrogen Estrogen Thyroid
Mechanism
Binds to estrogen receptors; competes with estradiol. Thyroid peroxidase inhibitors; inhibits thyroid hormone synthesis.
Atrazine Carbaryl Chlofentezine Chlordane Cypermethrin DDT
Neuroendocrine-pituitary Inhibits ligand binding to (depression of LH surge), androgen and estrogen testosterone metabolism. receptors. Estrogen and progesterone Thyroid Testosterone and progesterone Disruption of reproductive function Estrogen Enhances secretion of thyroid hormone.
DDT and related compounds act in a number of ways to disrupt endocrine function by binding with the estrogen receptor, including estrogen mimickry and antagonism, altering the pattern of synthesis or metabolism of hormones, and (4) modifying hormone receptor levels Inhibits androgen binding to the androgen receptor, androgeninduced transcriptional activity, and androgen action in developing, pubertal and adult male rats. Binds to estrogen receptor;competes with estradiol.
DDT Metabolite, p,p'-DDE
Androgen
Dicofol (Kelthane) Dieldrin
Estrogen Estrogen
Endosulfan Ethylene thiourea Fenarimol Fenbuconazole Fenitrothion Fenvalerate Fipronil Heptachlor Heptachlor-epoxide Iprodione Karate
Estrogen Thyroid Estrogen Thyroid Antiandrogen Estrogen Thyroid Thyroid Thyroid/Reproductive Inhibition of testosterone synthesis Thyroid
Thyroid peroxidase inhibitor. Estrogen receptor agonist. Enhances secretion of thyroid hormone. Competitive androgen receptor antagonist. Enhances secretion of thyroid hormone. Metabolite of heptachlor
Kepone (Chlordecone) Ketoconazole Lindane (Hexachlorocyclohexane) Linuron Malathion
Estrogen Effects on reproductive systems Estrogen/Androgen Androgen Thyroid
A decrease of thyroid hormone in serum; direct effect on the thyroid gland? Displays androgen and estrogen receptorbinding affinities.
Mancozeb Maneb
Thyroid Thyroid
Inhibits ligand binding to androgen and estrogen receptors. Androgen receptor antagonist. Significant decrease of thyroid hormone in serum, with perhaps a direct effect on the thyroid gland. Thyroid peroxidase inhibitors. The metabolite ethylenthiourea inhibits thyroid hormone synthesis. Through mechanisms other than receptor antagonism. Precise mechanism still unclear.
Methomyl Methoxychlor
Thyroid Estrogen
Metribuzin Mirex
Thyroid Antiandrogenic activity; inhibits production of LH. Potentially thyroid.
Nitrofen
Thyroid
Nonachlor, transOxychlordane Pendimethalin Pentachloronitrobenzene Permethrin Procymidone Prodiamine Pyrimethanil Sumithrin Tarstar
Estrogen Reproductive Thyroid Thyroid Estrogenic Androgen Thyroid Thyroid Androgen Thyroid
Structural similarities to the thyroid hormones; nitrofen or its metabolite may have thyroid hormone activities. Estrogen receptor agonist? Enhances secretion of thyroid hormone. Enhances secretion of thyroid hormone. Androgen receptor antagonist. Enhances secretion of thyroid hormone. Enhances secretion of thyroid hormone. A decrease of thyroid hormone in serum; direct effect on the thyroid gland? Enhances secretion of thyroid hormone.
Thiazopyr Thiram
Thyroid Neuroendocrine-pituitary (depression of LH surge), thyroid (decrease of T4, increase of TSH) Estrogen/ Thyroid Estrogen Estrogen Reproductive Reproductive/ Metabolic Androgen
Toxaphene Triadimefon Triadimenol Tributyltin Trifluralin Vinclozolin
Estrogen receptor agonist. Estrogen receptor agonist
Anti-androgenic. (Competes with androgens for the androgen receptor (AR), inhibits AR-DNA binding, and alters androgendependent gene expression.) The metabolite ethylenthiourea inhibits thyroid hormone synthesis.
Zineb
Thyroid
Ziram
Thyroid
Inhibits the iodide peroxidase. Structural similarities between ziram and thiram; ziram can be metabolized to thiram in the environment.
Phthalates Compound Butyl benzyl phthalate (BBP) Di-n-butyl phthalate (DBP) Di-ethylhexyl phthalate (DEHP) Diethyl Phthalate (DEP) Other Compounds Compound Benzophenone Hormones affected Estrogen Mechanism Binds weakly to estrogen receptors, roles of its metabolite remain to be clarified. Estrogenic; binds to estrogen receptor Estrogenic; b inds to estrogen receptor anti-androgenic Hormones affected Estrogen Estrogen, Androgen Estrogen, Androgen Estrogen Mechanism Inhibits binding to the estrogen receptor Inhibits binding to the estrogen receptor. Antiandrogenic Inhibits binding to the estrogen receptor. Antiandrogenic
Bisphenol A Bisphenol F Benzo(a)pyrene Carbendazim Ethane Dimethane Sulphonate Perfluorooctane sulfonate (PFOS) Nonylphenol, octylphenol
Estrogen Estrogen Androgen Reproductive Reproductive Thyroid, reproductive Estrogen
suppression of T3,T4; mechanism unknown Estrogen receptor agonists; reduces estradiol binding to the estrogen receptor. Estrogen receptor agonists
Resorcinol Styrene dimers and trimers
Thyroid Estrogen
Metals Compound Hormones affected Mechanism
Arsenic
Glucocorticoid
Cadmium
Estrogenic
Selective inhibition of DNA transcription normally stimulated by the glucocorticoid-GR complex. Activates estrogen receptor through an interaction with the hormone-binding domain of the receptor.
Lead Mercury
Reproductive Reproductive/ Thyroid
References Akhtar et al. 1996 Brittebo et al. 1987 Brittebo et al. 1987 Krishnan and Safe 1993, Klinge et al. 1999
Sandan et al. 2000 Bahn et al. 1980, Henderson et al. 1995 Korach et al. 1988, Zoeller et al. 2000, Grey et al. 1999
Cheek et al. 1999
Ilonka et al. 2000 Bear et al. 1999, Gerhard et al. 1999
References Jobling et al. 1995
References Hurley et al. 1998 Wilson et al. 1996 Jorgenson 2001 Go et al. 1999 Hurley et al. 1998
Danzo 1997 Klotz et al. 1997 Hurley et al. 1998 Willingham et al. 2000 Moore and Waring 2001 Soto et al. 1994, Lascombe et al. 2000, Kupfer et al. 1980, Rajapakse et al. 2001
Kelce 1995
Vinggaard et al. 1999 Arnold et al. 1997, Soto et al. 1994, Jorgenson 2001
Soto et al. 1994, Soto et al. 1995 Hurley et al. 1998 Vinggaard et al. 1999 Hurley et al. 1998 Tamura et al. 2001 Go et al. 1999 Hurley et al. 1998 Akhtar et al. 1996, Reuber 1987 Reuber 1987 Benhamed 1996 Akhtar et al. 1996
Waller et al. 1996, Soto et al. 1994, McLachlan(ed) Marty et al. 1999, Marty et al. 2001 Danzo 1997 Waller et al. 1996, Lambright et al. 2000, Grey et al. 1999 Akhtar et al. 1996
Hurley et al. 1998 Toppari et al. 1995
Porter et al. 1993, Klotz et al. 1997 Pickford and Morris 1999
Porter et al. 1993 Chen et al. 1986, Chernoff et al. 1976
Stevens and Summer 1991
Willingham et al. 2000 Guillette et al. 1999 Hurley et al. 1998 Hurley et al. 1998 Go et al. 1999 Ostby et al. 1999, Grey et al. 1999 Hurley et al. 1998 Hurley et al. 1998 Go et al. 1999 Akhtar et al. 1996
Hurley et al. 1998 Stoker et al. 1993
Soto et al. 1994 Vinggaard et al. 1999 Vinggaard et al. 1999 Horiguchi et al. 2000 Rawlings et al. 1998 Soto et al. 1994, Soto et al. 1995, Kelce et al. 1994, Grey et al. 1999
Toppari et al. 1995
Marinovich et al. 1997
References Jobling et al. 1995 Jobling et al. 1995, Harris et al. 1997, Grey et al. 1999 Jobling et al. 1995, Harris et al. 1997, Moore et al. 2001, Grey et al. 1999 Harris et al. 1997
References Schlumpf et al. 2001
Fisher et al. 1999, Anderson et al. 1999, Rajapakse et al. 2001 Perez et al. 1998 Thomas 1990 Gray et al. 1990 Gray et al. 1999 3M data Soto et al. 1991, Soto et al. 1995, Danzo 1997, Lascombe et al. 2000, Rajapakse et al. 2001
Lindsay et al. 1989 Ohyama et al. 2001
References
Kaltreider et al. 2001
Stoica et al. 2000, Johnson et al. 2003
Telisman et al. 2000, Hanas et al. 1999 Facemire et al. 1995
Persistent organohalogens Half-life in Lake (days) Compound(s) Benzenehexachloride (BHC) 1,2-dibromoethane Chloroform Dioxins and furans Octachlorostyrene PBBs PCBs PCB, hydroxylated PBDEs Pentachlorophenol Henry's Law Kd Solubility (l/kg) Log Kow Constant (mg/l) @ pH 6.8 (atmm3/mol) NA NA NA NA NA NA NA 2.00E+00 4.20E+03 7.40E-04 3.98E+01 NA 1.90E+00 7.90E+03 3.70E-03 Koc (l/kg) NA NA NA 3.09E+05 NA NA NA NA NA NA NA NA NA NA 6.50E+00 1.50E-02 NA NA NA NA 6.00E+00 7.00E-02 NA NA NA NA 5.10E+00 2.00E+03 NA NA NA 2.60E-03 NA NA 2.40E-08 Vapor Pressure Diffusivity (cm2/s) Bioconcentration Hydrolysis Volatility Biodegredation Hydrolysis Volatility Biodegredation Factor (Environmental) NA 1.80E+02 1.80E+02 NA NA NA NA NA NA 1.80E+02 NA NA 8.00E+02 1.30E+00 6.80E+05 1.00E+00 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.80E+02 1.80E+02 NA NA NA NA NA NA 1.80E+02 Half-life in River (days)
(Torr) NA NA NA NA NA 1.30E+01 NA NA 8.00E+02 1.20E+02 2.00E+02 0.104 (air) 6 (freshwater) 6.80E+05 9.60E+01 0.00001 (water) NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 7.70E-05 NA 270000 (freshwater), NA NA 670000 (saltwater) NA NA 3.20E-05 NA NA NA NA 0.056 (air) 1100 (freshwater) 0.0000061 (water) 390 (saltwater) NA NA NA NA NA NA
Food Antioxidant Half-life in Lake (days) Compound(s) Koc (l/kg) NA Henry's Law Vapor Kd Solubility Diffusivity (l/kg) Log Kow Constant Pressure (mg/l) (cm2/s) @ pH 6.8 (atmm3/mol) (Torr) NA NA NA NA NA NA Half-life in River (days)
Bioconcentration Factor Hydrolysis Volatility Biodegredation Hydrolysis Volatility Biodegredation (Environmental) NA NA NA NA NA NA NA
Butylated hydroxyanisole (BHA) Pesticides
Half-life in Lake (days) Compound(s) Acetochlor Alachlor Aldrin Allethrin, d-trans Amitrol Atrazine Carbaryl Chlofentezine Chlordane Cypermethrin DDT DDT Metabolite, p,p'-DDE Dicofol (Kelthane) Dieldrin Endosulfan Ethylene thiourea Fenarimol Fenbuconazole Fenitrothion Fenvalerate Fipronil Heptachlor Heptachlor-epoxide Karate Iprodione Kepone (Chlordecone) Kd Solubility Diffusivity (l/kg) Log Kow Constant Pressure (mg/l) (cm2/s) @ pH 6.8 (atmm3/mol) (Torr) NA NA NA NA NA NA NA NA NA NA NA NA NA NA 2.45E+06 NA 6.50E+00 1.80E-01 1.70E-04 6.00E-06 0.0132 (air) 0.00000486 (water) NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 2.60E+00 7.00E+01 NA 3.00E-07 NA NA NA 2.40E+00 1.00E+02 3.50E-09 1.40E-06 NA NA NA NA NA NA NA NA 1.20E+05 NA 6.30E+00 5.60E-02 4.90E-05 9.80E-06 0.0118 (air) 0.00000437 (water) NA NA NA NA NA NA NA 2.63E+06 NA 6.50E+00 2.50E-02 8.10E-06 1.60E-07 0.0137 (air) 0.00000495 (water) 4.47E+06 NA 6.80E+00 1.20E-01 2.10E-05 6.00E-06 0.0144 (air) 0.00000587 (water) NA NA 4.30E+00 1.30E+00 NA NA NA 2.14E+04 NA 5.40E+00 2.00E-01 1.50E-05 5.90E-06 0.0125 (air) 0.00000474 (water) 2.14E+03 NA 4.10E+00 5.10E-01 1.10E-05 1.00E-05 0.0115 (air) 0.00000455 (water) NA NA 6.60E-01 6.20E+04 3.10E-10 1.40E-04 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.41E+06 NA 6.30E+00 1.80E-01 1.50E+00 4.00E-04 0.0112 (air) 0.00000569 (water) 8.32E+04 NA 5.00E+00 2.00E-01 9.50E-06 1.90E-05 0.0132 (air) 0.00000423 (water) NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 5.30E+00 7.60E+00 2.50E-08 3.00E-07 NA Koc (l/kg) NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 3.70E+00 6.80E+00 NA NA 2.90E+00 1.40E+02 NA NA NA NA 3.40E-01 5.80E+04 5.10E+00 4.50E-02 1.70E+00 1.20E+03 6.90E+00 6.80E-03 NA NA NA NA NA NA NA NA 4.60E+00 5.50E-01 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 3.00E+01 5.50E+00 7.40E-01 NA NA NA NA NA NA 5.30E+00 8.10E+00 NA NA NA NA NA NA NA 1.40E-05 NA 4.90E-09 NA NA 3.80E-02 1.60E-05 8.80E-02 NA NA NA NA NA 3.80E-04 NA NA NA NA NA NA NA NA 6.00E-06 NA NA NA 2.60E-05 NA NA NA NA 4.10E-04 NA 7.90E-06 NA NA 3.00E+04 6.00E-07 4.00E+03 NA NA NA NA NA 1.10E-04 NA NA NA NA NA NA NA NA 9.80E-07 NA NA NA 4.80E-05 NA NA NA NA 0.0142 (air) 0.00000734 (water) NA NA NA NA NA 0.0156 (air) 0.00000446 (water) NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.0116 (air) 0.00000434 (water) NA NA NA NA NA NA NA Henry's Law Vapor
Half-life in River (days)
Bioconcentration Factor Hydrolysis Volatility Biodegredation Hydrolysis Volatility Biodegredation (Environmental) NA NA NA NA NA NA 140000 (freshwater) 8.00E+02 1.70E+02 NA NA 83 (freshwater) 10 (freshwater) NA 38000 (freshwater) 16000 (saltwater) NA NA NA NA 1.00E-01 NA 2.00E+01 NA NA NA 7.20E+07 1.80E+02 NA NA 5.90E+02 NA NA 7.40E+02 3.00E+01 NA 1.40E+03 NA 5.70E+03 5.80E+03 NA 1.10E+03 1.40E+01 2.80E+01 NA NA NA NA NA 6.50E+01 5.50E+02 NA NA 7.20E+02 NA 4.10E+02 NA 5.20E+01 NA NA NA 3.70E+02 NA NA NA NA NA NA 7.00E+02 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 8.00E+02 2.10E+00 NA NA NA NA 1.00E-01 NA 2.00E+01 NA NA NA 7.20E+07 2.90E+00 NA NA 3.70E+03 7.50E+00 NA 3.80E+00 NA NA 5.90E+02 NA NA 7.40E+02 3.00E+01 NA 1.40E+03 NA 5.70E+03 5.80E+03 NA 1.10E+03 1.40E+01 2.80E+01 NA NA NA NA NA 6.50E+01 5.50E+02 NA NA 7.20E+02 NA 4.10E+02 NA 5.20E+01 NA NA NA 3.70E+02 NA NA NA NA NA NA 7.00E+02 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA
NA NA NA 4400000 3.70E+03 1.70E+02 (freshwater) 7600000 (saltwater) 180000 (freshwater) NA 1.60E+02 19000 (freshwater) NA NA 68000 (freshwater) 4.00E+03 1.70E+02 8000 (saltwater) 12000 (freshwater) 2800 (saltwater) NA NA NA NA NA NA 14000 (freshwater) 37000 (saltwater) 14000 (freshwater) NA NA 11000 (freshwater) 60000 (saltwater) NA 310 (freshwater) 730 (saltwater) NA 38 (freshwater) NA NA NA 71000 (freshwater) 5400 (saltwater) NA 28000 (freshwater) 16000 (saltwater) NA NA NA NA 260 (freshwater) NA NA NA NA NA NA NA NA 52000 (freshwater) 33000 (saltwater) NA NA NA 24000 (freshwater) NA NA NA 9.10E+00 1.80E+02 NA NA NA NA NA NA NA NA NA NA NA NA 4.20E+00 1.70E+02 NA NA NA NA 7.00E+00 NA NA NA
NA NA 4.00E+03 5.00E+00 9.10E+00 6.30E+00 NA NA NA NA NA NA NA NA NA NA NA NA 4.20E+00 1.80E+00 NA NA NA NA 7.00E+00 NA NA NA
Ketoconazole NA Lindane (Hexachlorocyclohexane) 1.07E+03 Linuron Malathion Mancozeb Maneb Methomyl Methoxychlor Metribuzin Mirex Nitrofen Nonachlor, transOxychlordane Pendimethalin Pentachloronitrobenzene Permethrin Procymidone Prodiamine Pyrimethanil Sumithrin Tarstar Thiazopyr Thiram Toxaphene Triadimefon Triadimenol Tributyltin Trifluralin Vinclozolin Zineb Ziram Phthalate NA NA NA NA NA 9.77E+04 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 2.57E+05 NA NA NA NA NA NA NA
NA NA 1.30E+03 1.50E+02 NA NA 1.20E+01 NA NA NA NA NA 2.50E+02 1.10E+02 3.60E+01 1.70E+02 NA NA 1.30E+02 NA
NA NA 1.30E+03 4.60E+00 NA NA 1.20E+01 NA NA NA NA NA 2.50E+02 1.20E+00 3.60E+01 4.60E+00 NA NA 1.40E+00 NA
NA NA NA NA NA NA NA NA 9.90E+02 1.50E+02 NA NA NA NA NA NA NA NA NA NA NA NA NA NA 4.00E+01 NA 3.70E+03 1.90E+02 NA NA NA NA NA NA NA NA NA NA 1.60E+02 NA NA NA
NA NA NA NA NA NA NA NA 9.90E+02 1.70E+00 NA NA NA NA NA NA NA NA NA NA NA NA NA NA 4.00E+01 NA 3.70E+03 1.00E+01 NA NA NA NA NA NA NA NA NA NA 3.40E+00 NA NA NA
Half-life in Lake (days) Compound(s) Henry's Law Vapor Kd Solubility Diffusivity (l/kg) Log Kow Constant Pressure (mg/l) (cm2/s) @ pH 6.8 (atmm3/mol) (Torr) 5.75E+04 NA 4.80E+00 2.70E+00 1.30E-06 8.30E-06 0.0174 (air) 0.00000483 (water) 3.39E+04 NA 4.60E+00 1.10E+01 9.40E-10 7.30E-05 NA NA NA NA NA NA NA NA 2.88E+02 NA 2.50E+00 1.10E+03 4.50E-07 1.60E-03 0.0256 (air) 0.00000635 (water) Koc (l/kg)
Half-life in River (days)
Bioconcentration Factor Hydrolysis Volatility Biodegredation Hydrolysis Volatility Biodegredation (Environmental) 660 (freshwater) 6700 (freshwater) NA 120 (freshwater) NA 1.90E+02 7.00E+00 2.30E+01 NA 5.60E+01 NA 3.60E+01 7.00E+00 2.30E+01 NA 5.60E+01
Butyl benzyl phthalate (BBP) Di-n-butyl phthalate (DBP) Di-ethylhexyl phthalate (DEHP) Diethyl Phthalate (DEP)
2.00E+04 NA NA NA 8.40E+03 2.20E+02
2.00E+04 NA NA NA 8.40E+03 8.30E+01
Other Compounds Half-life in Lake (days) Half-life in River (days) Henry's Law Vapor Kd Bioconcentration Solubility Diffusivity Hydrolysis Volatility Biodegredation Hydrolysis Volatility Biodegredation (l/kg) Log Kow Constant Pressure Factor (mg/l) (cm2/s) @ pH 6.8 (atm(Environmental) m3/mol) (Torr) Benzophenone NA NA NA NA NA NA NA NA NA NA NA NA NA NA Bisphenol A NA NA NA NA NA NA NA NA NA NA NA NA NA NA Bisphenol F NA NA NA NA NA NA NA NA NA NA NA NA NA NA Benzo(a)pyrene 1.02E+06 NA 6.10E+00 1.60E-03 1.10E-06 5.50E-09 0.043 (air) 83000 (freshwater) NA 1.80E+02 5.30E+02 NA 3.60E+01 5.30E+02 0.000009 (water) 240 (saltwater) Carbendazim NA NA NA NA NA NA NA NA NA NA NA NA NA NA Ethane Dimethane Sulphonate NA NA NA NA NA NA NA NA NA NA NA NA NA NA Compound(s) Koc (l/kg) Perfluorooctane sulfo nate (PFOS) NA Nonylphenol, octylphenol NA Resorcinol NA Styrene dimers and trimers 7.76E+02 NA NA NA NA NA NA NA NA 7.80E-01 1.00E+06 2.90E+00 3.10E+02 NA NA 7.70E-09 2.70E-03 NA NA 4.50E-04 6.10E+00 NA NA NA 0.071 (air) 0.000008 (water) NA NA NA NA NA NA NA NA NA NA NA 9.00E+01 NA NA NA 2.80E+01 NA NA NA NA NA NA NA 9.70E-01 NA NA NA 2.80E+01
Metals Half-life in Lake (days) Compound(s) Koc (l/kg) NA NA NA NA Henry's Law Vapor Kd Solubility Diffusivity (l/kg) Log Kow Constant Pressure (mg/l) (cm2/s) @ pH 6.8 (atmm3/mol) (Torr) 2.90E+01 NA NA NA NA NA 7.50E+01 NA 5.20E+01 NA NA NA NA NA NA NA NA 1.10E-02 NA NA 2.00E-03 NA NA NA Half-life in River (days)
Bioconcentration Hydrolysis Volatility Biodegredation Hydrolysis Volatility Biodegredation Factor (Environmental) 350 (freshwater) 350 (saltwater) 7400 (freshwater) 3500 (saltwater) 1700 (freshwater) 2600 (saltwater) 86000 (freshwater) 40000 (saltwater) NA NA NA NA NA NA NA 1.20E+02 NA NA NA NA NA NA NA NA NA NA NA 1.30E+00 NA NA NA NA
Arsenic Cadmium Lead Mercury
References:
Log Kow, Solubility, Henry's Law Constant, Vapor Pressure, Bioconcentration Factor, and Half-lives are presented as listed in the Superfund Chemical Data Matrix (SCDM), Office of Emergency and Remedial Response, 1997. For further information, go to www.epa.gov/oerrpage/superfund/resources/scdm/index.htm Koc, Kd, and Diffusivity are presented as listed in the Environmental Protection Act Soil Screening Guidance, Part 5, EPA540/R-96/018, July 1996. For further information, go to risk.lsd.ornl.gov/calc_start.shtml. Notes: NA = Not available in the above-mentioned references
Persistent organohalogens Compound(s) Methods Benzenehexachloride (BHC) EPA Method 505 EPA Method 508 EPA Method 525 EPA Method 608 EPA Method 617 EPA Method 625 EPA Method 8080A EPA Method 8081 EPA Method 8250A 1,2-dibromoethane EPA Method 502.2 EPA Method 504 EPA Method 524.1 EPA Method 524.2 EPA Method 618 EPA Method 8010B EPA Method 8011 EPA Method 8021A EPA Method 8240B EPA Method 8260A Chloroform EPA Method 502.2 EPA Method 524.1 EPA Method 524.2 EPA Method 601 EPA Method 624 EPA Method 8010B EPA Method 8021A EPA Method 8240B EPA Method 8260A
Pesticides Compound(s) Methods Alachlor EPA Method 505 EPA Method 525 EPA Method 645 EPA Method 8081 Aldrin EPA Method 505 EPA Method 508 EPA Method 525 EPA Method 608 EPA Method 617 EPA Method 625 EPA Method 8080A EPA Method 8081 EPA Method 8250A Ethylene thiourea EPA Method 509 EPA Method 553 Atrazine EPA Method 505 EPA Method 525 EPA Method 619 EPA Method 8141A
Compound(s) Methods
Endosulfan EPA Method 508 EPA Method 608 EPA Method 617 EPA Method 625 EPA Method 8080A EPA Method 8081 EPA Method 8250A
Fenitrothion EPA Method 622.1 EPA Method 8141A
Compound(s) Methods
Methomyl EPA Method 531.1 EPA Method 632
Methoxychlor EPA Method 505 EPA Method 508 EPA Method 525 EPA Method 608.2 EPA Method 617 EPA Method 625
Metribuzin EPA Method 633
Methods
EPA Method 8080A EPA Method 8081 EPA Method 8250A Phthalates Compound(s) Methods Butyl benzyl phthalate (BBP) Di-n-butyl phthalate (DBP) Di-ethylhexyl phthalate (DEHP) EPA Method 525 EPA Method 606 EPA Method 625 EPA Method 8060 EPA Method 8061 EPA Method 8250A EPA Method 606 EPA Method 8060 EPA Method 8061 EPA Method 8250A EPA Method 525 EPA Method 606 EPA Method 625 EPA Method 8060 EPA Method 8061 EPA Method 8250A
Other Compounds Compound(s) Methods Benzo(a)pyrene EPA Method 525 EPA Method 610 EPA Method 625 EPA Method 8100 EPA Method 8250A EPA Method 8310
Metals Compound(s) Methods Arsenic EPA Method 200.7 EPA Method 200.8 EPA Method 200.9 EPA Method 206.2 EPA Method 6010 EPA Method 7060 Cadmium EPA Method 200.7 EPA Method 200.8 EPA Method 6010 EPA Method 60201 Lead EPA Method 200.7 EPA Method 200.8
Dioxins and furans EPA Method 613
PCBs
Pentachlorophenol
EPA Method 505 EPA Method 515.1 EPA Method 508 EPA Method 515.2 EPA Method 525 EPA Method 525 EPA Method 608 EPA Method 555 EPA Method 617 EPA Method 604 EPA Method 625 EPA Method 625 EPA Method 8080A EPA Method 8040A EPA Method 8081 EPA Method 8151 EPA Method 8250A EPA Method 8250A
Carbaryl EPA Method 531.1 EPA Method 553 EPA Method 632
Chlordane EPA Method 505 EPA Method 508 EPA Method 608 EPA Method 625 EPA Method 8080A EPA Method 8250A
DDT
DDT Metabolite, p,p'-DDE (Kelthane) Dicofol EPA Method 617 EPA Method 8081
EPA Method 508 EPA Method 508 EPA Method 608 EPA Method 608 EPA Method 617 EPA Method 617 EPA Method 625 EPA Method 625 EPA Method 8080A EPA Method 8080A EPA Method 8081 EPA Method 8081 EPA Method 8250A
Heptachlor
Heptachlor-epoxide Kepone (Chlordecone) Lindane EPA Method 8081 EPA Method 505 EPA Method 508 EPA Method 525 EPA Method 608 EPA Method 617 EPA Method 625 EPA Method 8080A EPA Method 8081 EPA Method 8250A
(gamma BHC) Linuron EPA Method 553 EPA Method 632
EPA Method 505 EPA Method 505 EPA Method 508 EPA Method 508 EPA Method 525 EPA Method 525 EPA Method 608 EPA Method 608 EPA Method 617 EPA Method 617 EPA Method 625 EPA Method 625 EPA Method EPA Method 8080A 8080A EPA Method 8081 EPA Method 8081 EPA Method EPA Method 8250A 8250A Mirex EPA Method 617 EPA Method 8081 Nitrofen EPA Method 8081
Nonachlor, trans- Pentachloronitrobenzene Permethrin EPA Method 505 EPA Method 617 EPA Method 8081 EPA Method 505 EPA Method 8081 EPA Method 525 EPA Method 8250A EPA Method 8081
Diethyl Phthalate (DEP) EPA Method 525 EPA Method 606 EPA Method 625 EPA Method 8060 EPA Method 8061 EPA Method 8250A
Dieldrin EPA Method 505 EPA Method 508 EPA Method 608 EPA Method 617 EPA Method 625 EPA Method 8080A EPA Method 8081 EPA Method 8250A
Malathion EPA Method 8141A
Toxaphene EPA Method 505 EPA Method 508 EPA Method 525 EPA Method 608 EPA Method 617 EPA Method 625
Trifluralin EPA Method 508 EPA Method 617 EPA Method 627 EPA Method 8081
EPA Method 8080A EPA Method 8081 EPA Method 8250A
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Below is a small sample set of documents:
Minnesota - ENHS - 5103
TOXICOLOGICAL PROFILE FOR POLYCHLORINATED BIPHENYLS (PCBs)U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health Service Agency for Toxic Substances and Disease RegistryNovember 2000PCBsiiDISCLAIMERThe use of company or product name(s)
Minnesota - CEHD - 18
ELLs with Disabilities Report 18Standards-based Instructional Strategies for English Language Learners with DisabilitiesNATIONAL CENTER ON E D U C AT I O N A L OUTCOMES In collaboration with:Council of Chief State School Officers (CCSSO) Nationa
Minnesota - CEHD - 17
ELLs with Disabilities Report 17Use of Chunking and Questioning Aloud to Improve the Reading Comprehension of English Language Learners with DisabilitiesNATIONAL CENTER ON E D U C AT I O N A L OUTCOMESIn collaboration with:Council of Chief Stat
Minnesota - CEHD - 16
ELLs with Disabilities Report 16Math Strategy Instruction for Students with Disabilities who are Learning EnglishNATIONAL CENTER ON E D U C AT I O N A L OUTCOMESIn collaboration with:Council of Chief State School Officers (CCSSO) National Assoc
Minnesota - CEHD - 14
ELLs with Disabilities Report 14Including English Language Learners with Disabilities in Large-Scale Assessments: A Case Study of Linguistically-Diverse PopulationsNATIONAL CENTER ON E D U C AT I O N A L OUTCOMES In collaboration with:Council of
Minnesota - CEHD - 12
ELLs with Disabilities Report 12ELL Parent Perceptions on Instructional Strategies for their Children with DisabilitiesNATIONAL CENTER ON E D U C AT I O N A L OUTCOMES In collaboration with:Council of Chief State School Officers (CCSSO) National
Minnesota - CEHD - 11
ELLs with Disabilities Report 11Student Perceptions of Instructional Strategies: Voices of English Language Learners with DisabilitiesNATIONAL CENTER ON E D U C AT I O N A L OUTCOMES In collaboration with:Council of Chief State School Ofcers (CC
Minnesota - CEHD - 10
ELLs with Disabilities Report 10Beyond Subgroup Reporting: English Language Learners with Disabilities in 2002-2003 Online State Assessment ReportsNATIONAL CENTER ON E D U C AT I O N A L OUTCOMES In collaboration with:Council of Chief State Scho
Minnesota - CEHD - 9
ELLs with Disabilities Report 9Confronting the Unique Challenges of Including English Language Learners with Disabilities in Statewide AssessmentsNATIONAL CENTER ON E D U C AT I O N A L OUTCOMES In collaboration with:Council of Chief State Schoo
Minnesota - CEHD - 8
ELLs with Disabilities Report 8Policymaker Perspectives on the Inclusion of English Language Learners with Disabilities in Statewide AssessmentsNATIONAL CENTER ON E D U C AT I O N A L OUTCOMES In collaboration with:Council of Chief State School
Minnesota - CEHD - 7
ELLs with Disabilities Report 7Educator Perceptions of Instructional Strategies for Standards-based Education of English Language Learners with DisabilitiesNATIONAL CENTER ON E D U C AT I O N A L OUTCOMES In collaboration with:Council of Chief S
Minnesota - CEHD - 6
ELLs with Disabilities Report 6English Language Learners with Disabilities and Large-Scale Assessments: What the Literature Can Tell UsNATIONAL CENTER ON E D U C AT I O N A L OUTCOMES In collaboration with:Council of Chief State School Ofcers (C
Minnesota - CEHD - 5
ELLs with Disabilities Report 5A Review of 50 States Online Largescale Assessment Policies: Are English Language Learners with Disabilities Considered?NATIONAL CENTER ON E D U C AT I O N A L OUTCOMES In collaboration with:Council of Chief State
Minnesota - CEHD - 4
ELLs with Disabilities Report 42000-2001 Participation and Performance of English Language Learners with Disabilities on Minnesota Standards-based AssessmentsNATIONAL CENTER ON E D U C AT I O N A L OUTCOMES In collaboration with:Council of Chief
Minnesota - CEHD - 3
ELLs with Disabilities Report 3Graduation Exam Participation and Performance (2000-2001) of English Language Learners with DisabilitiesNATIONAL CENTER ON E D U C AT I O N A L OUTCOMES In collaboration with:Council of Chief State School Ofcers (C
Minnesota - CEHD - 2
ELLs with Disabilities Report 2Graduation Exam Participation and Performance (1999-2000) of English Language Learners with DisabilitiesNATIONAL CENTER ON E D U C AT I O N A L OUTCOMES In collaboration with:Council of Chief State School Ofcers (C
Minnesota - CEHD - 1
ELLs with Disabilities Report 11999-2000 Participation and Performance of English Language Learners with Disabilities on Minnesota Standards-based AssessmentsNATIONAL CENTER ON E D U C AT I O N A L OUTCOMES In collaboration with:Council of Chief
Minnesota - CEHD - 15
Out-of-Level Testing Report 15Educators Opinions About Out-of-Level Testing: Moving Beyond PerceptionsNATIONAL CENTER ON E D U C AT I O N A L OUTCOMES In collaboration with:Council of Chief State School Ofcers (CCSSO) National Association of Sta
Minnesota - CEHD - 14
Out-of-Level Testing Report 14States Procedures for Ensuring Out-ofLevel Test Instrument QualityNATIONAL CENTER ON E D U C AT I O N A L OUTCOMES In collaboration with:Council of Chief State School Ofcers (CCSSO) National Association of State Dir
Minnesota - CEHD - 13
Out-of-Level Testing Report 13Rapid Changes, Repeated Challenges: States Out-of-Level Testing Policies for 2003-2004NATIONAL CENTER ON E D U C AT I O N A L OUTCOMES In collaboration with:Council of Chief State School Ofcers (CCSSO) National Asso
Minnesota - CEHD - 12
Out-of-Level Testing Report 12Understanding Out-of-Level Testing in Local Schools: A Second Case Study of Policy Implementation and EffectsNATIONAL CENTER ON E D U C AT I O N A L OUTCOMES In collaboration with:Council of Chief State School Ofcer
Minnesota - CEHD - 11
Out-of-Level Testing Report 11Understanding Out-of-Level Testing in Local Schools: A First Case Study of Policy Implementation and EffectsNATIONAL CENTER ON E D U C AT I O N A L OUTCOMES In collaboration with:Council of Chief State School Ofcers
Minnesota - CEHD - 10
Out-of-Level Testing Report 10Reporting Out-of-Level Test Scores: Are These Students Included in Accountability Programs?NATIONAL CENTER ON E D U C AT I O N A L OUTCOMES In collaboration with:Council of Chief State School Ofcers (CCSSO) National
Minnesota - CEHD - 9
Out-of-Level Testing Report 9Testing Students with Disabilities Out of Level: State Prevalence and Performance ResultsNATIONAL CENTER ON E D U C AT I O N A L OUTCOMES In collaboration with:Council of Chief State School Ofcers (CCSSO) National As
Minnesota - CEHD - 5
LEP Projects Report 5Connecting English Language Prociency, Statewide Assessments, and Classroom PerformanceNATIONAL CENTER ON E D U C AT I O N A L OUTCOMES In collaboration with:Council of Chief State School Ofcers (CCSSO) National Association
Minnesota - CEHD - 4
LEP Projects Report 4Relationships Between a Statewide Language Prociency Test and Academic Achievement AssessmentsNATIONAL CENTER ON E D U C AT I O N A L OUTCOMES In collaboration with:Council of Chief State School Ofcers (CCSSO) National Assoc
Minnesota - CEHD - 20
NCEODIRECTIONSPOLICYalignment of alternate assessment based on alternate achievement standards with grade-level content standards. It also address guidance for maximizing resources spent to determine alignment of the AAAAS.There are several
Minnesota - CEHD - 19
NCEODIRECTIONSPOLICYwith information on issues that complicate alignment of alternate assessments based on alternate achievement standards. It also provides information on existing alignment models that can be used for alignment studies. A compa
Minnesota - CEHD - 17
NCEODIRECTIONSPOLICYbudgets have to occur to make the goal achievable. Some educators see a need to improve assessments so that they inform instruction on grade level content. These educators are calling for assessments based on a limited
Minnesota - CEHD - 16
Essential components of inclusive assessment systems that must be understood and addressed are student participation in assessments, testing accommodations, alternate assessments, reporting results, and accountability. The implementation of these c
Minnesota - CEHD - 15
NCEODIRECTIONSPOL I CYComputer-based testing is viewed by many policymakers as a way to meet the requirements of the No Child Left Behind Act of 2001 (NCLB). The need to produce itemized score analyses, disaggregation within each school an
Minnesota - CEHD - 14
NCEODIRECTIONSPOL I CYsions are made. Research to validate accommodation use is growing, but the research is difficult to conduct and rarely provides conclusive evidence about the effects of accommodations on validity. States grapple wit
Minnesota - APEC - 30
PAYING FOR AGRICULTURAL PRODUCTIVITYJULIAN M. ALSTON, PHILIP G. PARDEY, AND VINCENT H. SMITH, EDITORSTFOODPOLICYSTATEMENTNUMBER 30, OCTOBER 1999hroughout the twentieth century improvements in agricultural productivity have been closely linke
Minnesota - APEC - 2007
CURRICULUMVITAE PHILIPGORDONPARDEYPERSONAL ContactAddress: UniversityofMinnesota DepartmentofAppliedEconomics CollegeofAgricultural,FoodandEnvironmentalSciences 1994BufordAvenue 218JClassroomOfficeBuilding StPaul,MN551086040 Tel:(612)6252766 Fax:
Minnesota - APEC - 2007
Philip Pardey, an Australian native, is Professor of Science and Technology Policy in the Department of Applied Economics at the University of Minnesota where he also directs the Universitys International Science and Technology Practice and Policy (I
Minnesota - EVPP - 08
September2007 TO: Chancellors,ViceChancellors,SeniorVicePresidents,VicePresidents,Deans, Directors,DepartmentChairs/Heads,andStudentOrganizations E.ThomasSullivan,SeniorVicePresidentforAcademicAffairsandProvost NominationGuidelinesforTwoAwardstoRecog
Minnesota - EVPP - 08
20072008AWARDFOROUTSTANDINGCONTRIBUTIONSTO POSTBACCALAUREATE,GRADUATE,ANDPROFESSIONALEDUCATION Purpose Commencingin19981999,theUniversityofMinnesotarecognizedaselectgroupof facultymembersfortheiroutstandingcontributionstopostbaccalaureate,graduate,an
Minnesota - EVPP - 09
September2008 TO: Chancellors,ViceChancellors,SeniorVicePresidents,VicePresidents,Deans, Directors,DepartmentChairs/Heads,andStudentOrganizations E.ThomasSullivan,SeniorVicePresidentforAcademicAffairsandProvost NominationGuidelinesforTwoAwardstoRecog
Minnesota - EVPP - 09
20082009AWARDFOROUTSTANDINGCONTRIBUTIONSTO POSTBACCALAUREATE,GRADUATE,ANDPROFESSIONALEDUCATION Purpose Commencingin19981999,theUniversityofMinnesotarecognizedaselectgroupof facultymembersfortheiroutstandingcontributionstopostbaccalaureate,graduate,an
Minnesota - STAT - 5601
5601 Notes: SmoothingCharles J. Geyer April 8, 2006Contents1 Web Pages 2 The General Smoothing Problem 3 Some Smoothers 3.1 Running Mean Smoother . . 3.2 General Kernel Smoothing . . 3.3 Local Polynomial Smoothing 3.4 Smoothing Splines . . . . .
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