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Course: BIOL D103, Winter 2008School: UC Irvine
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David Luis Gomez 59866865 Week 10 Bio 192 D103 Cell Biology Lecture 26 Outline 3/10/08 Meiosis--What is it? Production of gamates Function Genetic Diversity Survival Error Prone Trisomies Monosomies Non-disjuctions at Maternal M1--as eggs sit in ovary, COHESINS degrade over time and separation of chromosomes occurs Stage of Meiosis *Leptitine--chromosomes are really thin Bouquet- -sister chromatids bunch up...
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David Luis Gomez 59866865
Week 10 Bio 192 D103 Cell Biology
Lecture 26 Outline 3/10/08
Meiosis--What is it? Production of gamates Function Genetic Diversity Survival Error Prone Trisomies Monosomies Non-disjuctions at Maternal M1--as eggs sit in ovary, COHESINS degrade over time and separation of chromosomes occurs Stage of Meiosis *Leptitine--chromosomes are really thin Bouquet- -sister chromatids bunch up *Zygotene- -homologs come together and pair up *Pachytene--thick chromosomes (undergo homlog pairing and make synaptonemal complex) between the two bivalves forms complex a a protein that allows recombination *Diplotene--synaptonemal complex removes, formation of chisma (sites or recombination --Leads to meiosis I Prior to Anaphase I Monopolin is a protein that binds MT to inside of kinetechores to stop MAD protein from halting anaphase
Comparison between Meiosis and Mitosis (2 Key differences) Meiosis-Chromosomes line up NEXT to each other so that they can undergo recombination 2 cell divisions--only undergoes S phase one time Mitosis-Chromosomes line up vertically
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How Chromosomes line up on metaphase spindle?
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