of School Biomedical Engineering, Science and Health Systems
Drexel BIOMED
School of Biomedical Engineering, Science & Health Systems
Bossone Research Enterprise Center
by
Banu Onaral, Director 23 December 2006
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School of Biomedical Engineering, Science and Health Systems
Our Founder
H. H. Sun
Professor Emeritus
OUR LEGACY
Biomedical Ultrasound Pioneer
John M. Reid
Professor Emeritus
V 1.0 [MS 041019]
School of Biomedical Engineering, Science and Health Systems
Presentation Outline
Outline
Life Saving Solutions About Drexel BIOMED
Bio-Nanotechnology BIOIMAGING BIOSENSING
BIOINFORMATICS
NEUROENGINEERING
TISSUE ENGINEERING
Biomedical Ultrasound
Biomedical Optics
V 1.0 [MS 041019]
School of Biomedical Engineering, Science and Health Systems
Life Saving... Solutions ...
"Educational...Experiences" ...
V 1.0 [MS 041019]
School of Biomedical Engineering, Science and Health Systems
Life Saving...
Drug Delivery Platforms
Breast & Prostate Cancer
>> Targeted and drug loaded contrast agents
Before...
Margaret Wheatley BIOMED
After...
Kelleny Oum BIOMED
Flemming Forsberg Thomas Jefferson University
...for ultrasonic imaging and therapeutics.
Berry Goldberg Thomas Jefferson University
...Solutions
V 1.0 [MS 041019]
School of Biomedical Engineering, Science and Health Systems
Life Saving...
Drug Delivery Platforms
Diseased Arteries, Cancerous Tumors...
>> Drug Eluting Stent
Ken Barbee BIOMED
Uniform magnetic field External Magnet
Gary Friedman Electrical Engineering
Magnetically Magnetic patterned Drug insert (stent) Carriers Illustration of the magnetically targeted delivery
Magnetizable stent for targeted drug delivery.
Ben Yellen Zach Forbes Electrical Engineering BIOMED Doctoral Students and Entrepreneurs in Residence
...Solutions
V 1.0 [MS 041019]
School of Biomedical Engineering, Science and Health Systems
Life Saving...
Near Infrared Based Optical Imaging Platform
Diabetic Wounds
>> Functional Optical Wound Monitor
Elisabeth Papazoglou BIOMED
Kambiz Pourrezaei BIOMED
Michael S. Weingarten Surgery, COM
...Solutions
V 1.0 [MS 041019]
School of Biomedical Engineering, Science and Health Systems
Life Saving...
Near Infrared Based Optical Imaging Platform
Traumatic Brain Injury
>> HematoscopeTM
Drexel Optical Brain Imaging Team
Hasan Ayaz BIOMED
Han Ryoo BIOMED
HematoscopeTM Hand-held Near Infrared Intracranial Hematoma Detector
Neal Handley Emergency Medicine, COM Baruch Ben Dor Herbert Patrick Entrepreneur in Residence Critical Care, COM
...Solutions
V 1.0 [MS 041019]
School of Biomedical Engineering, Science and Health Systems
Life Saving...
Near Infrared Based Optical Imaging Platform
Autism, Schizophrenia, Dementia...
>> Functional Optical Brain Imaging Sensor
Drexel Optical Brain Imaging Team
Meltem Izzetoglu BIOMED Scott Bunce Psychiatry, COM Kurtulus Izzetoglu BIOMED
fNIR Sensor
Personality and psychiatric disorders.
Steve Platek Psychology
...Solutions
V 1.0 [MS 041019]
School of Biomedical Engineering, Science and Health Systems
Life Saving...
Cellular Tissue Engineering Platform
Immature Lungs at Birth
>> Tissue Engineered Lungs
Peter Lelkes BIOMED
Christine Finck Pediatric Neurosurgery, COM
Mark Mondrinos BIOMED
Christopher Koharski BIOMED
...Solutions
V 1.0 [MS 041019]
School of Biomedical Engineering, Science and Health Systems
Life Saving...
Cellular Tissue Engineering Platform
Non-healing Wounds & Life Threatening Burns
>> Tissue Engineered Skin Scaffold
Peter Lelkes BIOMED
Frank Ko Materials Engineering
Mengyan Li BIOMED
Anat Katsir BIOMED
...Solutions
V 1.0 [MS 041019]
School of Biomedical Engineering, Science and Health Systems
Life Saving...
Acoustic Nano-biosensor Platform
Stroke, Thrombosis, Heart Failure...
>> Blood Coagulation Biosensor
BioSensus
Capillary
Ryzard Lec BIOMED
INR = 2.0 PT = 27 ...........
Blood Sample Piezoelectric Transducer
Mode
Calibration
Start
Blood Sample
Disposable Blood BioChip
Yasha Kresh Cardiothoracic Surgery
Disposable NanoAcoustic Blood Analyzer (NABA)
David Wootton Mechanical Engineering
...Solutions
V 1.0 [MS 041019]
School of Biomedical Engineering, Science and Health Systems
Life Saving...
Cellular Nanoprobe Platform
Real-time Nano-biopsy
>> Nano-size probes for intracellular imaging.
UV light needle -like fiber Som Tyagi Physics Cell under inverted microscope
<150 nm
YY
Elisabeth Papazoglou BIOMED
Collect/Count Photons
Quantify Concentration Kambiz Pourrezaei BIOMED
Antibody functionalized nano-particle coated probes.
Irvin Chaiken Biochemistry, COM
Nikolay Popnikolof Pathology, COM
...Solutions
V 1.0 [MS 041019]
School of Biomedical Engineering, Science and Health Systems
Strategic Thrusts & Leadership
Biosensing & Bioimaging
Biomedical Ultrasound & Optics Biosensors Drug Delivery Imaging; Contrast Agents
Peter Lewin
Professor of Biomedical & Electrical Engineering
Banu Onaral
After Encapsulation
Day 3
Margaret Wheatley
Professor of Biomedical & Chemical Engineering
Brass housing Solution Piezoelectric Plate
Professor & Director School of Biomedical Engineering, Science and Health Systems
Day 7
Day 12
Kambiz Pourrezaei
Professor of Biomedical & Electrical Engineering
V 1.0 [MS 041019]
Ryszard Lec
Professor of Biomedical & Electrical Engineering
O-ring Electrode
School of Biomedical Engineering, Science and Health Systems
Strategic Thrusts & Leadership
BioNanotechnology
Biosensors & Cellular Probes Drug Delivery Tissue Engineering
Peter I. Lelkes
Calhoun Chair Professor of Cellular Tissue Engineering
Kambiz Pourrezaei Ryszard Lec
Professor of Biomedical & Electrical Engineering Professor of Biomedical & Electrical Engineering
Margaret Wheatley
Professor of Biomedical & Chemical Engineering
V 1.0 [MS 041019]
School of Biomedical Engineering, Science and Health Systems
Strategic Thrusts & Leadership
Cellular Tissue Engineering
Cellular Engineering Biomaterials
Peter I. Lelkes
Calhoun Chair Professor of Cellular Tissue Engineering
Fred Allen
Assistant Professor of Biomedical Engineering
Dov Jaron
Calhoun Distinguished Professor, Biomedical Engineering
IMPLANT RESEARCH INITIATIVE
Director: Steven Kurtz, Drexel University & Exponent Inc. Associate Directors: Michele Marcolongo & Av Edidin Drexel University Kyphon Corp.
V 1.0 [MS 041019]
Kenneth A. Barbee
Associate Professor of Biomedical Engineering
School of Biomedical Engineering, Science and Health Systems
Strategic Thrusts & Leadership
Neuroengineering
Brain Machine Interface Computational Neuroscience and Neuroinformatics Neurorobotics Neuropharmaceutical Engineering Biomechanics and Human Performance
CP G
Hip
Karen Moxon
Assistant Professor of Biomedical Engineering & Neurobiology
Ank le Kn ee
Ilya Rybak
Research Professor of Biomedical Engineering and Neurobiology
Rami Seliktar
Professor & Vice Director of School of Biomedical Engineering, Science & Health Systems
Todd C. Doehring
Assistant Professor of Biomedical Engineering
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School of Biomedical Engineering, Science and Health Systems
Strategic Thrusts & Leadership
Integrated Bioinformatics
Center for Integrated Bioinformatics
Director: Aydin Tozeren
Aydin Tozeren
Distinguished Professor of Biomedical Engineering
Bioinformatics Bioinformation Engineering Bioimaging
Clustering Algorithm
Andres Kriete
Associate Professor of Bioinformation Engineering / Director of Biocomputing Laboratory at Coriell Institute for Medical Research
Bahrad A Sokhansanj
Assistant Professor of Biomedical Engineering
V 1.0 [MS 041019]
School of Biomedical Engineering, Science and Health Systems
Strategic Thrusts & Leadership
New Initiatives
Skin Bioengineering
Pediatric Engineering
Arye Rosen
Academy Professor & Director, Pediatric Engineering Program
Elizabeth Papazoglou
Research Associate Professor of Biomedical Engineering
Samuel Neff
Pediatric Engineering St. Christophers Pediatric Hospital
V 1.0 [MS 041019]
School of Biomedical Engineering, Science and Health Systems
Regional Initiatives & Leadership
Translational Research Roadmap
Research & Development
Basic Applied and Research
ROAD MAP
Laboratory Prototype
Clinical Prototype & Preclinical Testing
Clinical Clinical Development, Development Testing and Validation Regulatory Regulatory Pathway Pathway
Commercialization & Manufacturing
Health Care Product
Translational Research
Market Assessment Freedom to Operate Regulatory & Reimbursement...
Business Plan
FUNDS
Federal and State Agencies, Corporate R&D, Private Foundations... SBIR, STIR, Corporate Ventures, Private Foundations, Private Investors...
THE Gap
V 1.0 [MS 041019]
School of Biomedical Engineering, Science and Health Systems
Regional Initiatives & Leadership
Our Region
Greater Philadelphia
Many firsts...
First Hospital: Pennsylvania Hospital, Founded by Ben Franklin in 1751 First Medical School for Women (now part of Drexel) First Children's Hospital, 1855...
Life sciences and engineering intellectual capital
...Largely untapped $1 Billion in R&D Funds to Academic Institutions ...$600 Million from NIH Ranked 3rd in Life Sciences Composite Index in Milken Institute Report, June 2005 ...Current strength and growth potential Ranked 1st in Current Impact Assessment Index ...Success in bringing research ideas to marketplace
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School of Biomedical Engineering, Science and Health Systems
Regional Initiatives & Leadership
Our Region (Continued)
Greater Philadelphia (Continued)
Network of Economic Development Agencies
...Committed to life sciences and biomedical technologies "Co-funding & commercialization infrastructure"
Regional Mobilization
Rethinking Philadelphia Reinventing Philadelphia
Action Philadelphia NOW!
Location... Location... Location...
...Midway between New York and Washington D.C. ...Midway between capital and regulatory centers
V 1.0 [MS 041019]
School of Biomedical Engineering, Science and Health Systems
About Drexel BIOMED
Our University
Culture and History of Drexel University
Founder A. J. Drexel's Legacy
...Higher education's critical role in economic development and wealth creation
Cooperative Education Entrepreneurial spirit and enterprising approach...
Office of Technology Commercialization Baiada Center for Entrepreneurship in Technology
Merger that created our College of Medicine
Synergy grants... Tobacco grants funded GRID program
New College of Law
Health law... Entrepreneurship
V 1.0 [MS 041019]
School of Biomedical Engineering, Science and Health Systems
About Drexel BIOMED
Our University (Continued)
Interdisciplinary team spirit at Drexel Technology Commercialization Performance
Relative to R&D Expenditure, Drexel has one of the highest start-up formation rates in the nation Funded Start-Ups in 2003... Drexel University: Research Expenditure $82 Million
6 Start-ups
7.4 Start-Ups per $100 Million
Stanford University: Research Expenditure $640 Million
12 Startups
3.3 Start-Ups per $100 Million
MIT: Research Expenditure $994 Million
15 Startups
1.5 Start-Ups per $100 Million
Source: Association of University Technology Managers
V 1.0 [MS 041019]
School of Biomedical Engineering, Science and Health Systems
About Drexel BIOMED
Our School
History
Created in 1961 as a free-standing university-level research institute
Biomedical Engineering and Science Institute offered masters and doctoral degrees in biomedical engineering and biomedical sciences
Calhoun Endowment Reorganized as a School September 1997
Following two years of strategic planning
Inaugural undergraduate class September 1998
ABET Accredited 2002
Founding Vision
Marriage of technology with biology and medicine is defining the industrial enterprise of the 21st century
V 1.0 [MS 041019]
School of Biomedical Engineering, Science and Health Systems
About Drexel BIOMED
Our School (Continued)
Mandate
Establish leadership in niche areas
Strive for clinical and industrial relevance Focus on translational research and entrepreneurship
Technology transfer and commercialization
Integrate academic assets and resources of the University and the region...
...through Strategic Partnerships ...Grassroots
V 1.0 [MS 041019]
School of Biomedical Engineering, Science and Health Systems
About Drexel BIOMED
Our School (Continued)
Unique Organizational Structure (Continued)
Free-standing university-level interdisciplinary unit that:
Transcends disciplinary barriers Facilitates the interplay between diverse groups Mobilizes and engages faculty of various programs Plays up the synergies and leverages expertise Orchestrates university-level challenge initiatives
Agility to respond to emerging opportunities
...Grassroots
Powerful regional alliances
Networks that sustain and nourish strategic initiatives
V 1.0 [MS 041019]
School of Biomedical Engineering, Science and Health Systems
About Drexel BIOMED
Our School (Continued)
Strategic Positioning
Strategic Academic Thrusts
Bio-Nanotechnology BIOIMAGING BIOSENSING
BIOINFORMATICS
NEUROENGINEERING
Biosen...