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Course: ABP 1130, Fall 2009
School: Uni. Westminster
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50 Fluid, Chapter Electrolyte and Acid Base Balance Body fluids and electrolytes Distribution of body fluids Intracellular Extracellular Interstitial Intravascular Composition of body fluids Electrolytes Ions + Anions Movement of body fluids and electrolytes Osmosis Diffusion Filtration Active transport Regulating body fluids Fluid intake Fluid output Urine Insensible losses Feces...

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50 Fluid, Chapter Electrolyte and Acid Base Balance Body fluids and electrolytes Distribution of body fluids Intracellular Extracellular Interstitial Intravascular Composition of body fluids Electrolytes Ions + Anions Movement of body fluids and electrolytes Osmosis Diffusion Filtration Active transport Regulating body fluids Fluid intake Fluid output Urine Insensible losses Feces Maintaining homeostasis Kidneys Control fluid and electrolyte excretion Antidiuretic hormone (ADH) Synthesized by anterior hypothalamus Regulates water excretion from kidney Maintaining homeostasis Reninangiotensinaldosterone Atrial natriuretic factor Receptors in kidney respond to perfusion Promotes H2O and electrolyte retention Stimulates release of aldosterone to reabsorb sodium in the distal nephron Atrial wall stretching stims this factor to dump sodium and therefore H2O Fluid imbalances Fluid volume deficit Fluid volume excess Third space syndrome Edema Dehydration Overhydration Fluid replacement Isotonic Fluid has the same osmolarity as plasma Normal Saline (N/S or 0.9% NaCl), Ringers Lactate (RL) Fluid replacement Hypotonic Fluid has fewer solutes than plasma Water, 1/2 N/S (0.45% NaCl), and D5W (5% dextrose in water) after the sugar is used up Fluid replacement Hypertonic Fluid has more solutes than plasma saline solution, D5 in RL. 5 % Dextrose in Normal Saline (D5 N/S), 3% ACID Acids are anything which gives off H+ ions In the body CO2 acts as an acid (forms The lower the pH, the more acid is present carbonic acid) Lungs are the mechanism primary for regulating CO2 BASE Bases are anything that absorb H+ ions The higher the pH, the more base is present In the body HCO3 acts as a base (buffers the acids) Kidneys are the primary mechanism for regulating HCO3 Respiratory Acidosis Low pH caused by High CO2 Causes High HCO3 will develop later to help balance pH COPD CHF Head injury with respiratory depression Lung Cancer Pneumonia Asthma Respiratory Alkalosis High pH caused by Low CO2 Causes Low HCO3 will develop later to help balance pH Fever Severe Pain Anxiety ASA overdose Thyrotoxicosis Overventilation with a mechanical ventilator Metabolic Acidosis Low pH caused by Low HCO3 Caused by anything which increases respirations Low HCO3 will develop later to help balance pH Fever Severe Pain Anxiety ASA overdose Thyrotoxicosis Overventilation with a mechanical ventilator Metabolic Alkalosis High pH caused by High HCO3 Causes High CO2 develops quickly to help balance pH Prolonged Vomiting Prolonged NG suctioning Excessive intake of HCO3 antacids Prolonged diuretic therapy with K+ wasting diuretics Determining Imbalance If pH is low (acidosis) look at CO2 If CO2 is high, it's respiratory acidosis If HCO3 is low it's metabolic acidosis Determining Imbalance If pH is high (alkalosis) look at CO2 If CO2 is low, its respiratory alkalosis If HCO3 is high, its metabolic alkalosis Nursing diagnoses Deficient fluid volume Excess Fluid volume Risk for Imbalanced fluid volume Risk for Deficient fluid volume Impaired Gas Exchange
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