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Lecture 26: Cytokines by <a href="/keyword/innate-immune/" >innate immune</a> cells 1. Overview of cytokine production through TLR 2. Viruses and TLR/RIG-I: DNA viruses are recognized by TLR9 &amp; RNA viruses by TLR7 in PDC RNA viruses are recognized by RIG-I in cDC/fibroblasts Drosophila innate immunity pathways PGRP: Peptidoglycan Recognition Protein...
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Lecture 26: Cytokines by <a href="/keyword/innate-immune/" >innate immune</a> cells 1. Overview of cytokine production through TLR 2. Viruses and TLR/RIG-I: DNA viruses are recognized by TLR9 & RNA viruses by TLR7 in PDC RNA viruses are recognized by RIG-I in cDC/fibroblasts Drosophila innate immunity pathways PGRP: Peptidoglycan Recognition Protein Approaches in innate immunity research: 1. Isolation of TLR genes by homology to Drosophila Toll (Medzhitov) and by mouse genetics between LPS sensitive and resistant strains (Beutler). 2. A yeast tw...
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