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lecture4
Course: BIOS 423, Spring 2008School: N. Illinois
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Lecture 4 Structure 1. Virion structure 2. Packaging the nucleic acid 3. Enveloped virions 1. Virion structure Protein structure 1 Cryo-electron microscopy: image reconstruction X-ray diffraction Structure of HIV 2 Building a protective coat Capsids with icosahedral symmetry T=4 triangulation of icosahedral face Triangulation number T 3 T, cont. Simple capsid: poliovirus Poliovirus capsid, cont., protein...
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Lecture 4 Structure 1. Virion structure 2. Packaging the nucleic acid 3. Enveloped virions 1. Virion structure Protein structure 1 Cryo-electron microscopy: image reconstruction X-ray diffraction Structure of HIV 2 Building a protective coat Capsids with icosahedral symmetry T=4 triangulation of icosahedral face Triangulation number T 3 T, cont. Simple capsid: poliovirus Poliovirus capsid, cont., protein interactions 4 SV-40 polyomavirus Adenovirus capsid Complex icosahedral capsids 5 Packaging the Nucleic Acid Genome Direct contact of NA with the shell: Reoviridae Bluetongue virus Human reovirus Double RNA within rotavirus shell 6 More about retrovirus capsid HIV Viruses with envelopes 7 Structure of a typical glycoprotein <a href="/keyword/herpes-simplex-virus/" >herpes <a href="/keyword/simplex-virus/" >simplex virus</a> </a> type 1 virion proteins Sindbis virus 8 Herpesvirus Nucleocapsid Simian cytomegalovirus Single portal and model Other virion components Homework for this week: Read and understand Chapter 4 in the book. Pay special attention to: -helical capsids: TMV, M-13, V...
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