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18 Pages
Edwards2005
Course: BNFO 301, Spring 2008School: VCU
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presentation This uses animations and is best viewed as a slide show. To start the presentation, click Slide Show on the top tool bar and then View show Introduction to Bioinformatics Monday, 26 February 2007 Welcome to Introduction to Viral Metagenome Project Discussion of Edward & Rohwer (2005)* Exam retrospective (Problem 12) *Unless otherwise noted, all figures herein are from: Edwards RA,...
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presentation This uses animations and is best viewed as a slide show.
To start the presentation, click Slide Show on the top tool bar and then View show
Introduction to Bioinformatics
Monday, 26 February 2007
Welcome to
Introduction to Viral Metagenome Project
Discussion of Edward & Rohwer (2005)* Exam retrospective (Problem 12)
*Unless otherwise noted, all figures herein are from: Edwards RA, Rohwer F (2005). Viral metagenomics. Nature Rev Microbiol (2005) 3:504-510.
Edwards & Rohwer (2005)
What is metagenomics?
SQ2. Genome sequencing vs metagenomic sequencing? What special challenges?
Edwards & Rohwer (2005)
What is metagenomics?
SQ4. ~Nucleotides of read sequence available?
Edwards & Rohwer (2005)
What is metagenomics?
SQ4. ~Nucleotides of read sequence available? Coverage if only 1 virus?
Edwards & Rohwer (2005)
What is metagenomics?
SQ4. ~Nucleotides of read sequence available? Coverage if only 1 virus? If 5000 viruses?
Edwards & Rohwer (2005)
What is metagenomics?
SQ3. Metagenomic sequencing ... why do it? Alternatives?
Edwards & Rohwer (2005)
Diversity of environmental viruses
SQ5. Significance of gray?
Edwards & Rohwer (2005)
Diversity of environmental viruses
SQ5. Significance of gray? Why faecal sample weird?
Edwards & Rohwer (2005)
Diversity of environmental viruses
SQ6. column Imagine for microbial metagenome
Edwards & Rohwer (2005)
Phage phylogeny and taxonomy Taxonomy
SQ8. Taxonomy vs Phylogeny
P2-like phage
T4-like phage
The Big Picture Book of Viruses: Myoviridae. Virology Journal http://www.virology.net/Big_Virology/BVDNAmyo.html
Edwards & Rohwer (2005)
Phage phylogeny and taxonomy Phylogeny
SQ8. Taxonomy vs Phylogeny
Martin W, Embley TM (2004). Nature 431:134-136
Edwards & Rohwer (2005)
Phage phylogeny and taxonomy Phylogeny
SQ8. Taxonomy vs Phylogeny Why not virion characteristics?
Martin W, Embley TM (2004). Nature 431:134-136
Edwards & Rohwer (2005)
Phage phylogeny and taxonomy Phylogeny
SQ8. Taxonomy vs Phylogeny Why not virion characteristics? Sequence-based?
Martin W, Embley TM (2004). Nature 431:134-136
Edwards &...
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