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Kine 198-Diseases

Course: KINE 198, Spring 2007
School: Texas A&M
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9 "Habits Diseases Chapter are to the soul what the veins and arteries are to the blood, the courses in which it moves." - Horace Bushnell Objectives Differentiate between communicable and noncommunicable diseases Identify the symptoms of various diseases List 5 strategies which should be utilized by members of their age group to avoid contraction of these diseases Know the risk factors...

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9 "Habits Diseases Chapter are to the soul what the veins and arteries are to the blood, the courses in which it moves." - Horace Bushnell Objectives Differentiate between communicable and noncommunicable diseases Identify the symptoms of various diseases List 5 strategies which should be utilized by members of their age group to avoid contraction of these diseases Know the risk factors for cancer Identify the seven warning signs of cancer Be able to list the steps for the BSE and TSE Objectives cont... List important aspects of periodic self/doctor examinations Differentiate between Type I and Type diabetes List three risk factors for Type II diabetes Define and describe anemia Know the signs and symptoms of anemia Identify three possible causes of ulcers Communicable Diseases Transmitted from person to person Transmission can occur by: Direct transmission Coughing or sneezing Indirect transmission Contaminated water or infected insects Types HIV/AIDS Tuberculosis Mononucleosis Hepatitis Common Cold Influenza HIV/AIDS Non-sexual contraction through blood transfusions, sharing needles, and or the exchange of blood or breast milk from a mother to her unborn or newborn child High risk groups IV drug users Individuals receiving a blood transfusion before 1985 Tuberculosis Why have rates risen in the past decade??? Affects the lungs Caused by the bacillus microorganism Mycobacterium tuberculosis Transmitted by airborne droplets when someone with active TB coughs, talks, or sneezes Tuberculosis cont... Latent TB Will have a positive skin test Not ill Cannot infect others May develop TB later in life Tuberculosis cont... Active TB Infants, adolescents, & young adults are at risk Symptoms: fatigue, weight loss, lethargy, decreased appetite, low grade fever, and night sweats A cough generally develops slowly Infections involves the lungs, but can spread to other parts of the body One half of untreated individuals will die With treatment, 5 10% will die Tuberculosis cont... Diagnosis Chest x-ray Culture and microscopic examination Treatment Active TB: combination of medication Treatment failure due to the development of drugresistant strains, caused by the irregularity in taking medications Mononucleosis Transmitted by saliva exchange Majority of cases occur in 15 30 yr olds Caused by the Epstein-Barr virus, which attacks the lymphocytes Symptoms Initially, mild symptoms of headache & fatigue Followed by, lymph node enlargement and sore throat Mononucleosis cont... Medical concerns Enlargement of the spleen Rare but possible complications, such as hepatitis, meningitis, encephalitis, and coma Diagnosis Blood test that detects the Epstein-Barr virus Treatment Bed rest, adequate hydration, non-aspirin analgesics Hepatitis "Inflammation of the liver" Causes of Hepatitis Alcohol or drug induced inflammation Virus most common 6 different viruses (A, B, C, D, E, & G) Viral hepatitis is a major public health concern 5,000,000 people are infected with Hepatitis B or C Hepatitis cont... Hepatitis can cause: Rapid liver failure and death Cirrhosis and/or liver cancer a slower process Hepatitis A & B - more likely to cause symptoms Hepatitis B & C - more likely to contribute to long-term health problems Hepatitis A Public Health Concern Diagnosis can be alarming With advances in treatment, there is hope for recovery especially when treatment is started early in the course of the illness Prevention and testing are also important factors Hepatitis A Poses the least threat Transmission: contact with food or water which has been contaminated with infected human waste OR direct person-to-person transmission May be no symptoms at all, but commonly there are "flulike" symptoms The course of the illness varies from mild symptoms lasting 1-2 weeks to severe symptoms lasting several months Hepatitis A cont... Individuals at risk: Household or sexual contacts of infected individuals Children in day care settings and their adult caretaker Patients and caretakers in institutionalized settings Recent travelers to developing countries Diagnosis: Detecting elevated liver enzymes and antibodies against Hepatitis A Hepatitis A cont... Treatment: Analgesics for pain IV fluids in the presence of excessive vomiting to prevent dehydration Prevention: Careful hand washing Proper sewage disposal Effective water treatment developed countries Vaccine is available Recommended if traveling to a country with poor sanitation Hepatitis C The most serious viral hepatitis to date Transmission is similar to Hepatitis B Risk factors: Blood transfusion prior to 1992 IV drug abuse Most who contract the virus have no symptoms Some will have "flu-like" symptoms Hepatitis C cont... 85% of those infected will develop a chronic infection If left untreated, an individual is at higher risk for cirrhosis, liver cancer, liver failure Hepatitis C cont... Diagnosis: Testing liver enzymes levels & hepatitis C antibodies Treatment: Interferon Rebetron No vaccine available Meningitis Infection of the fluid of a person's spinal cord and the fluid that surrounds the brain Viral Meningitis Most common Less severe Treatment: bed rest, fluids, medicine to relieve fever and headaches Bacterial Meningitis Can cause blindness, deafness, permanent brain damage, learning disability, or even death Can be treated successfully with antibiotics if caught early Classic symptoms: high fever, severe headache, a stiff neck, and a skin rash that looks like small, purplish red spots Other symptoms: nausea, vomiting, discomfort looking into bright lights, confusion, and sleepiness Symptoms can take anywhere from 2-10 days after close exposure to someone with meningitis Meningitis cont... Diagnosis: spinal tap Spread by direct contact through respiratory and throat secretions (e.g., coughing, sneezing, kissing, and immediate sharing of unwashed eating utensils) There should be special concern if someone in your household or dorm, daycare, or intimate partner has contracted meningitis Common Cold Caused by several different viruses Transmitted directly or indirectly Symptoms: congestion, sneezing, sore throat, coughing, and a low-grade fever Medication can ease symptoms Influenza (Flu) Viral infection of the nose, throat, bronchial tubes, and lungs Transmission similar to the common cold Symptoms: high fever, chills, headache, muscle and joint ache, coughing and fatigue Cold vs. the Flu Is It a Cold or the Flu??? Reducing the Risk of Contracting the Cold and/or Flu Wash hands often Do not touch infected areas Drink plenty of water Adequate rest Avoid using handkerchiefs Vitamin C Flu shot Non-Communicable Diseases Not transmitted from person to person Develops from many sources: Genetic predisposition Lifestyle factors Sun exposure Smoking Physical inactivity Unhealthy eating habits Types Cancer Asthma Diabetes Cancer Characterized by the growth of abnormal cells Tumors are benign or malignant Classified by cell type and organ origination of 4 classifications: 1) 2) 3) 4) Carcinoma Sarcomas Leukemias Lymphomas Risk Factors Family history: 10% of all cancers Race and culture Carcinogens: 80-90% of all cancers Environmental Sun and occupational hazards exposure Cigarette smoking Viruses Alcohol consumption Poor dietary habits 7 Warning Signs of Cancer 1. Change in bowel or bladder habits 2. A sore not healing 3. Unusual bleeding or discharge 4. Thickening lumps 5. Indigestion or difficulty swallowing 6. Obvious change in wart or mole 7. Nagging cough or hoarseness Cancer cont... WHAT IS THE KEY TO BEATING CANCER??? Treatment: Surgery Radiation Chemotherapy Immunotherapy Skin Cancer Most common form of cancer 90% occur on parts of the body not usually covered by clothes (face, hands, forearms, & ears) Types of Skin Cancer The two most common: cell carcinoma Squamous cell carcinoma The fatality rate is less than one percent Less Basal prevalent: melanoma Incidence is rising 4-5% each year Malignant Risk factors blond or red hair freckling on upper back rough red bumps on skin family history of melanoma 3 or more blistering sunburns as a teenager 3 or more years at an outdoor job as a teenager living in the southern United States Skin cancer cont... risk increases 3-4 times w/ 1 or 2 characteristics risk increases 20-25 times w/ 3+ characteristics Prevention Avoid sun when your shadow is shorter than you Cover up when in the sun Use sunscreen with SPF 15 or greater Beware of cloudy days, water, and snow Avoid tanning beds Early Detection Skin Self-Exam (SSE) each month Start with the head and work downward Follow the "ABCD rule" Asymmetry Border Color Diameter Performed Lung Cancer #1 cause of cancer deaths in U.S. 85% of all lung cancer deaths are caused by smoking Other carcinogens: asbestos, secondhand smoke, radiation and radon exposure Is there early detection for lung cancer??? Symptoms: chest pain, shortness of breath recurring bronchitis or pneumonia weight loss or loss of appetite nagging cough anemia Breast Cancer Most common form among women (besides skin cancer) Risk factors: Age 40 and older family history early onset of menstruation having no children or at a late age late menopause obesity Breast Cancer cont... What is the best way to reduce mortality rates among breast cancer patients??? Women age 20 + should perform monthly BSE's Routine mammograms by age 40 Breast Self Exams: Look for masses within the tissue or changes in appearance Conduct self exam at the same time each month One week after the beginning of the menstrual period Breast Self Exams cont... Procedures: Mirror Bath or Shower Lying Down Cervical Cancer Mainly affects young women No symptoms in the early stages Symptoms: uterine bleeding, cramps, infections, pain in the abdominal region Risk Factors: 1st vaginal intercourse at an early age, multiple sex partners, infections with certain types of HPV's, & cigarette smoking Pap Smear A check for pre-cancerous cells or early cancer of the cervix Can help prevent up to 90% of cervical cancer When should you have your first pap smear? How often should you have a pap smear? Testicular Cancer Most common cancer among younger males (ages 15 34) Risk Factors: Greatest Risk factor: undescended testicle as a child Other risk factors: family history, inguinal hernia, testicular trauma, mumps, elevated testicular temperature, & vasectomy Testicular Cancer cont... Check with your physician: If there is a general feeling of heaviness in the testicles If the whole testicle feel harder than usual If one side of your scrotum is very swollen If you feel a lump or hard area in the testicles Any skin sores, bumps, or other changes in your genitals that do not seem normal Testicular Self Exams Exams should begin at age 15 How often should you perform a TSE??? When should you perform a TSE??? Procedures: Mirror After a Bath or Shower Oral Cancers Cancers of the lip, tongue, mouth, and pharynx Risk factors: tobacco & excessive alcohol use Early symptoms: a bleeding sore that will not heal, a lump or thickening, a red or white patch (lesion) that will not go away, a persistent sore throat, difficulty chewing, swallowing or moving of the tongue or jaws Asthma Respiratory disorder which involves difficulty breathing Individuals will notice a wheezing sound In some cases, an individual can remove themselves from an irritant Most attacks require medical intervention Asthma cont... Risk factors: family history, exposure to certain allergens, certain viral infections, and cigarette smoke Individuals are twice as likely to have asthma, if their mother smoked Most children outgrow the condition Diabetes Insufficient insulin production by the pancreas OR The body's inability to utilize insulin 2 functions of insulin move glucose from blood to cells convert glucose to glycogen Types of diabetes: Type I and Type II Type I Diabetes associated with child or adolescent onset pancreas does not produce insulin requires regular injections Symptoms: fatigue, irritability, abnormal hunger or thirst, frequent urination, and weight loss symptoms appear suddenly and dramatically Treatment: monitor blood glucose and adjust the amount of insulin injected Type II Diabetes Associated with adult onset and obesity Insulin produced, but the cells of the body do not use it effectively Symptoms: drowsiness, blurred vision, itching, slow healing of cuts, skin infections, & numbness of fingers and toes symptoms appear gradually Type II Diabetes cont... Complications: Diabetic coma, seizures, strokes, heart attacks, gangrene of the lower extremities, & blindness Leading cause of blindness among adults Accounts for half of all amputations Treatment: Healthy diet Regular exercise Maintain healthy body weight and fat levels In some instances, insulin may be required Summary Communicable diseases are transmitted directly and indirectly Tuberculosis affects the lungs Mononucleosis attacks the lymphocytes Hepatitis is an inflammation of the liver Common cold is caused by several different viruses Influenza (Flu) is a viral infection of the nose, throat, bronchial tubes, and lungs Non-communicable diseases develop from genetic predispositions and lifestyle factors The 7 warning signs of cancer aid in the early detection of cancer Summary cont... Skin Self-Exams, Breast Self-Exams, Mammograms, Pap Smears, and Testicular Self-Exams, Digital Rectal Exams, Stool Blood Tests, & Proctosigmoidoscopy help with the early detection of cancer Asthma is a respiratory disorder which involves difficulty breathing Diabetes results from either an insufficient insulin production by the pancreas or the body's inability to utilize insulin There are 4 different types of Anemia Gastrointestinal disorders include ulcers and irritable bowel syndrome Local Contacts and Websites Texas A&M University Health Center 845-1511 Center for Disease Control and Prevention www.cdc.gov American Cancer Society www.cancer.org American Diabetes Association www.diabetes.org
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Texas A&M - KINE - 198
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CHAPTER 2Section 2.11.a. S = { 1324, 1342, 1423, 1432, 2314, 2341, 2413, 2431, 3124, 3142, 4123, 4132, 3214, 3241, 4213, 4231 } Event A contains the outcomes where 1 is first in the list: A = { 1324, 1342, 1423, 1432 } Event B contains the outcome
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CHAPTER 7Section 7.11. a.z 2 = 2.81 implies that 2 = 1 - (2.81) = .0025 , so = .005 and the confidencelevel is 100 1 -()% = 99.5% .b. c.z 2 = 1.44 for = 2[1 - (1.44)] = .15 , and 100(1 - )% = 85% .99.7% implies that = .003 , 2
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CHAPTER 9Section 9.11. a.E (X - Y ) = E( X ) - E (Y ) = 4.1 - 4.5 = -.4 , irrespective of sample sizes.V ( X - Y ) = V (X ) + V (Y ) =of2 12 2 (1 .8) (2.0) = .0724 , and the s.d. + = + m n 100 100 2 2b.X - Y = .0724 = .2691 .c.A norm
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CHAPTER 15Section 15.11.H 0 : = 100 vs. H a : 100 . The test statistic is s + = sum of the ranks associated with the positive values of ( xi - 100) , and we reject Ho at significance level .05 if s + 64 . (from Table A.13, n = 12, with / 2 =
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CHAPTER 14Section 14.11. a. We reject Ho if the calculated 2 value is greater than or equal to the tabled value of2 , k -1 from Table A.7. Since 12.25 .2 , 4 = 9.488 , we would reject Ho . 05b. c. d.Since 8.54 is not Since 4.36 is not
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