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Course: BIOSTAT 8472, Fall 2009
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Areal Bayesian Wombling for Geographic Boundary Analysis Haolan Lu, Haijun Ma, and Bradley P. Carlin haolanl@biostat.umn.edu, haijunma@biostat.umn.edu, and brad@biostat.umn.edu Division of Biostatistics School of Public Health University of Minnesota Bayesian Areal Wombling for Geographic Boundary Analysis p. 1/3 Background Spatial data typically classified two ways: point-referenced (geostatistical): spatial...

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Areal Bayesian Wombling for Geographic Boundary Analysis Haolan Lu, Haijun Ma, and Bradley P. Carlin haolanl@biostat.umn.edu, haijunma@biostat.umn.edu, and brad@biostat.umn.edu Division of Biostatistics School of Public Health University of Minnesota Bayesian Areal Wombling for Geographic Boundary Analysis p. 1/3 Background Spatial data typically classified two ways: point-referenced (geostatistical): spatial locations are points with known coordinates areal (lattice): locations are geographic regions (e.g., counties) with adjacency information Bayesian Areal Wombling for Geographic Boundary Analysis p. 2/3 Background Spatial data typically classified two ways: point-referenced (geostatistical): spatial locations are points with known coordinates areal (lattice): locations are geographic regions (e.g., counties) with adjacency information Important topic in spatial statistics: boundary analysis, wherein we seek to identify regions of abrupt change. Indicated by: steep gradients in a continuous surface regional boundaries separating regions with drastically different measurements in a lattice surface Bayesian Areal Wombling for Geographic Boundary Analysis p. 2/3 Background Spatial data typically classified two ways: point-referenced (geostatistical): spatial locations are points with known coordinates areal (lattice): locations are geographic regions (e.g., counties) with adjacency information Important topic in spatial statistics: boundary analysis, wherein we seek to identify regions of abrupt change. Indicated by: steep gradients in a continuous surface regional boundaries separating regions with drastically different measurements in a lattice surface Focus in this talk: Boundary analysis for areal data Bayesian Areal Wombling for Geographic Boundary Analysis p. 2/3 Background (cont'd) Spatial boundary analysis techniques often called wombling, after a foundational paper by Womble (1951). Bayesian Areal Wombling for Geographic Boundary Analysis p. 3/3 Background (cont'd) Spatial boundary analysis techniques often called wombling, after a foundational paper by Womble (1951). In areal (or polygonal) wombling, a dissimilarity metric measures the difference between adjacent regions. Methods for choosing boundary elements: absolute (dissimilarity metrics greater than C ) relative (dissimilarity metrics in the top k %) Bayesian Areal Wombling for Geographic Boundary Analysis p. 3/3 Background (cont'd) Spatial boundary analysis techniques often called wombling, after a foundational paper by Womble (1951). In areal (or polygonal) wombling, a dissimilarity metric measures the difference between adjacent regions. Methods for choosing boundary elements: absolute (dissimilarity metrics greater than C ) relative (dissimilarity metrics in the top k %) Problems: Relative (top k %) thresholding method always finds a fixed number of boundary elements Approach is algorithmic, rather than stochastic: no model or likelihood, so statements about the "significance" of a detected boundary only relative to predetermined, often unrealistic null distributions. Bayesian Areal Wombling for Geographic Boundary Analysis p. 3/3 Crisp vs. Fuzzy Areal Wombling Suppose we have responses Zi for regions i = 1, . . . , n For neighboring regions i and j and some distance metric || ||, assign the boundary likelihood value (BLV) Dij = ||Zi - Zj || . Bayesian Areal Wombling for Geographic Boundary Analysis p. 4/3 Crisp vs. Fuzzy Areal Wombling Suppose we have responses Zi for regions i = 1, . . . , n For neighboring regions i and j and some distance metric || ||, assign the boundary likelihood value (BLV) Dij = ||Zi - Zj || . Crisp wombling: Boundary is those edges having BLV's above specified thresholds, i.e., for some c > 0, {(i, j) : Dij > c, i adjacent to j} . Bayesian Areal Wombling for Geographic Boundary Analysis p. 4/3 Crisp vs. Fuzzy Areal Wombling Suppose we have responses Zi for regions i = 1, . . . , n For neighboring regions i and j and some distance metric || ||, assign the boundary likelihood value (BLV) Dij = ||Zi - Zj || . Crisp wombling: Boundary is those edges having BLV's above specified thresholds, i.e., for some c > 0, {(i, j) : Dij > c, i adjacent to j} . Fuzzy wombling: Partial membership in the boundary is permitted, say by defining the boundary membership values (BMVs) Dij / max{Dij } ij Bayesian Areal Wombling for Geographic Boundary Analysis p. 4/3 Example: MN colorectal cancer data Here ni is the total number of colorectal cancers occurring in county i, and Yi is the number of these that were detected late. Let Yi Zi = SLDRi = , i = 1, . . . , N , Ei the standardized late detection ratio (SLDR), where the expected counts are computed via internal standardization as Ei = ni r, and r = i Yi / i ni , the statewide late detection rate. Bayesian Areal Wombling for Geographic Boundary Analysis p. 5/3 Example: MN colorectal cancer data Here ni is the total number of colorectal cancers occurring in county i, and Yi is the number of these that were detected late. Let Yi Zi = SLDRi = , i = 1, . . . , N , Ei the standardized late detection ratio (SLDR), where the expected counts are computed via internal standardization as Ei = ni r, and r = i Yi / i ni , the statewide late detection rate. Left panel of next slide shows BoundarySEER plots of traditional wombled boundaries... Bayesian Areal Wombling for Geographic Boundary Analysis p. 5/3 Example: MN colorectal cancer data Left: BoundarySeer choropleth map of colorectal cancer late detection SLDRs, and crisp wombled boundaries arising from the top 20% (red) and 50% (yellow) of the Dij . Bayesian Areal Wombling for Geographic Boundary Analysis p. 6/3 Example: MN colorectal cancer data Left: BoundarySeer choropleth map of colorectal cancer late detection SLDRs, and crisp wombled boundaries arising from the top 20% (red) and 50% (yellow) of the Dij . Right: "Tricked" BoundarySeer map of fitted Bayesian colorectal cancer detection SLDRs, and Bayesian wombled boundaries based on the top 20% of the E(ij |y) values using G = 1500 Gibbs samples. Bayesian Areal Wombling for Geographic Boundary Analysis p. 6/3 Hierarchical modeling approach We employ the Poisson log-linear form Yi P oisson(i ) where log i = log Ei + x + i . i where xi are region-specific covariates, and Bayesian Areal Wombling for Geographic Boundary Analysis p. 7/3 Hierarchical modeling approach We employ the Poisson log-linear form Yi P oisson(i ) where log i = log Ei + x + i . i where xi are region-specific covariates, and the random effects = (1 , . . . , N ) are given a conditionally autoregressive CAR( ) specification, i | j=i N (i , 1/( mi )) , where N denotes the normal distribution, i is the average of the j=i that are adjacent to i , and mi is the number of these adjacencies. Bayesian Areal Wombling for Geographic Boundary Analysis p. 7/3 Hierarchical modeling approach Define the BLV for boundary (i, j) as ij = |i - j | for all i adjacent to j , with i = i /Ei . Bayesian Areal Wombling for Geographic Boundary Analysis p. 8/3 Hierarchical modeling approach Define the BLV for boundary (i, j) as ij = |i - j | for all i adjacent to j , with i = i /Ei . BLVs' posterior distribution = wombled boundaries! Bayesian Areal Wombling for Geographic Boundary Analysis p. 8/3 Hierarchical modeling approach Define the BLV for boundary (i, j) as ij = |i - j | for all i adjacent to j , with i = i /Ei . BLVs' posterior distribution = wombled boundaries! Crisp: Define ij to be part of the boundary if and only if E(ij |y) > c for some constant c > 0, or if and only if P (ij c | y) > c for some constant 0 < c < 1. Bayesian Areal Wombling for Geographic Boundary Analysis p. 8/3 Hierarchical modeling approach Define the BLV for boundary (i, j) as ij = |i - j | for all i adjacent to j , with i = i /Ei . BLVs' posterior distribution = wombled boundaries! Crisp: Define ij to be part of the boundary if and only if E(ij |y) > c for some constant c > 0, or if and only if P (ij c | y) > c for some constant 0 < c < 1. Fuzzy: P (ij c | y) is itself the fuzzy BMV, with MC estimate and associated sd pij = ^ (g) #ij >c G and pij (1 - pij ) ^ ^ , G retaining only every M th sample, for a total of G. Bayesian Areal Wombling for Geographic Boundary Analysis p. 8/3 MN colorectal cancer data revisited means pij : ^ associated sd's: Posterior probability areal wombling maps for the Minnesota colorectal cancer detection data using three illustrative values of c (5, 15, and 30%), M = 5, and G = 2000. Bayesian Areal Wombling for Geographic Boundary Analysis p. 9/3 MN colorectal cancer data revisited The probability of each segment being a member of the boundary decreases in c (the threshold for being a BE) Bayesian Areal Wombling for Geographic Boundary Analysis p. 10/3 MN colorectal cancer data revisited The probability of each segment being a member of the boundary decreases in c (the threshold for being a BE) The p maps suggest little evidence of strong boundaries ^ between counties; only a few county boundaries estimated to separate regions with true SLDRs that differ by more than 15%. Bayesian Areal Wombling for Geographic Boundary Analysis p. 10/3 MN colorectal cancer data revisited The probability of each segment being a member of the boundary decreases in c (the threshold for being a BE) The p maps suggest little evidence of strong boundaries ^ between counties; only a few county boundaries estimated to separate regions with true SLDRs that differ by more than 15%. The standard deviation plots reveal that the overall uncertainty associated with each segment tends to decrease for the more extreme c (5 and 30), as we become more certain that most segments either are or are not part of the boundary. Bayesian Areal Wombling for Geographic Boundary Analysis p. 10/3 MN colorectal cancer data revisited The probability of each segment being a member of the boundary decreases in c (the threshold for being a BE) The p maps suggest little evidence of strong boundaries ^ between counties; only a few county boundaries estimated to separate regions with true SLDRs that differ by more than 15%. The standard deviation plots reveal that the overall uncertainty associated with each segment tends to decrease for the more extreme c (5 and 30), as we become more certain that most segments either are or are not part of the boundary. Animated sequences of crisp boundaries (as in www.biostat.umn.edu/haolanl/movie.gif) may be more enlightening than maps of posterior standard deviations... Bayesian Areal Wombling for Geographic Boundary Analysis p. 10/3 MN colorectal cancer data revisited To assess whether County 63 (Red Lake, a T-shaped county in the NW) is truly "isolated" from its only two neighbors (Counties 57 and 60), by evaluating p63 P (63,57 > c 63,60 > c | y) . ~ Bayesian Areal Wombling for Geographic Boundary Analysis p. 11/3 MN colorectal cancer data revisited To assess whether County 63 (Red Lake, a T-shaped county in the NW) is truly "isolated" from its only two neighbors (Counties 57 and 60), by evaluating p63 P (63,57 > c 63,60 > c | y) . ~ Since the {ij } come from the joint posterior of {ij }, Monte Carlo estimates are available = simultaneous inference without a multiple comparisons problem (i.e. no need for Bonferroni correction). (g) Bayesian Areal Wombling for Geographic Boundary Analysis p. 11/3 MN colorectal cancer data revisited To assess whether County 63 (Red Lake, a T-shaped county in the NW) is truly "isolated" from its only two neighbors (Counties 57 and 60), by evaluating p63 P (63,57 > c 63,60 > c | y) . ~ Since the {ij } come from the joint posterior of {ij }, Monte Carlo estimates are available = simultaneous inference without a multiple comparisons problem (i.e. no need for Bonferroni correction). If we womble the spatial residuals i (instead of the i ), (g) Bayesian Areal Wombling for Geographic Boundary Analysis p. 11/3 MN colorectal cancer data revisited To assess whether County 63 (Red Lake, a T-shaped county in the NW) is truly "isolated" from its only two neighbors (Counties 57 and 60), by evaluating p63 P (63,57 > c 63,60 > c | y) . ~ Since the {ij } come from the joint posterior of {ij }, Monte Carlo estimates are available = simultaneous inference without a multiple comparisons problem (i.e. no need for Bonferroni correction). If we womble the spatial residuals i (instead of the i ), Boundaries now separate regions with differing unmodeled heterogeneity = help identify missing covariates! (g) Bayesian Areal Wombling for Geographic Boundary Analysis p. 11/3 MN colorectal cancer data revisited To assess whether County 63 (Red Lake, a T-shaped county in the NW) is truly "isolated" from its only two neighbors (Counties 57 and 60), by evaluating p63 P (63,57 > c 63,60 > c | y) . ~ Since the {ij } come from the joint posterior of {ij }, Monte Carlo estimates are available = simultaneous inference without a multiple comparisons problem (i.e. no need for Bonferroni correction). If we womble the spatial residuals i (instead of the i ), Boundaries now separate regions with differing unmodeled heterogeneity = help identify missing covariates! No significant boundaries = (covariate-adjusted) mapwide equity, a.k.a. "environmental justice" (g) Bayesian Areal Wombling for Geographic Boundary Analysis p. 11/3 Alternative: Modeling adjacency Note that the univariate CAR model can be written as i | (-i) N j wij j j wij , 1 j wij , where the weights wij are equal to 1 if i = j and regions i and j are adjacent, and 0 otherwise. Bayesian Areal Wombling for Geographic Boundary Analysis p. 12/3 Alternative: Modeling adjacency Note that the univariate CAR model can be written as i | (-i) N j wij j j wij , 1 j wij , where the weights wij are equal to 1 if i = j and regions i and j are adjacent, and 0 otherwise. The CAR remains a valid distributional specification provided 0 wij 1 = more possibilities for spatial smoothing: Bayesian Areal Wombling for Geographic Boundary Analysis p. 12/3 Alternative: Modeling adjacency Note that the univariate CAR model can be written as i | (-i) N j wij j j wij , 1 j wij , where the weights wij are equal to 1 if i = j and regions i and j are adjacent, and 0 otherwise. The CAR remains a valid distributional specification provided 0 wij 1 = more possibilities for spatial smoothing: Choose the wij inversely proportional to the distance separating the centroids of regions i and j , or Bayesian Areal Wombling for Geographic Boundary Analysis p. 12/3 Alternative: Modeling adjacency Note that the univariate CAR model can be written as i | (-i) N j wij j j wij , 1 j wij , where the weights wij are equal to 1 if i = j and regions i and j are adjacent, and 0 otherwise. The CAR remains a valid distributional specification provided 0 wij 1 = more possibilities for spatial smoothing: Choose the wij inversely proportional to the distance separating the centroids of regions i and j , or Think of the wij as additional unknown parameters to be estimated, allowing the data to help determine the degree and nature of spatial smoothing. Bayesian Areal Wombling for Geographic Boundary Analysis p. 12/3 Alternative: Modeling adjacency Mimicking an idea from statistical social network analysis (Wang and Wong, 1987; Hoff et al., 2002), model the wij as wij |pij Bernoulli(pij ) , where log pij 1 - pij = z . ij Bayesian Areal Wombling for Geographic Boundary Analysis p. 13/3 Alternative: Modeling adjacency Mimicking an idea from statistical social network analysis (Wang and Wong, 1987; Hoff et al., 2002), model the wij as wij |pij Bernoulli(pij ) , where log pij 1 - pij = z . ij Example: Let z1ij = 1 (so that 1 is an intercept parameter), z2ij = dij , the distance between the centroids of regions i and j , z3ij = (areai + areaj )/2, the average area of the two regions, and z4ij = |xi - xj |, the absolute difference of some regional covariate (say, percent urban, or percent of residents who are smokers). Bayesian Areal Wombling for Geographic Boundary Analysis p. 13/3 Alternative: Modeling adjacency Crisp boundaries based on wij : those segments ij having P (wij = 0 | y) > c . Bayesian Areal Wombling for Geographic Boundary Analysis p. 14/3 Alternative: Modeling adjacency Crisp boundaries based on wij : those segments ij having P (wij = 0 | y) > c . Fuzzy boundaries based on wij : use the P (wij = 0 | y) values themselves as the BMVs. Bayesian Areal Wombling for Geographic Boundary Analysis p. 14/3 Alternative: Modeling adjacency Crisp boundaries based on wij : those segments ij having P (wij = 0 | y) > c . Fuzzy boundaries based on wij : use the P (wij = 0 | y) values themselves as the BMVs. Reilly (2001) showed is estimable even under a noninformative prior. Bayesian Areal Wombling for Geographic Boundary Analysis p. 14/3 Alternative: Modeling adjacency Crisp boundaries based on wij : those segments ij having P (wij = 0 | y) > c . Fuzzy boundaries based on wij : use the P (wij = 0 | y) values themselves as the BMVs. Reilly (2001) showed is estimable even under a noninformative prior. MCMC sampling of , , , , and W can proceed by a tuned mixture of Gibbs and Metropolis steps. Bayesian Areal Wombling for Geographic Boundary Analysis p. 14/3 Alternative: Modeling adjacency Crisp boundaries based on wij : those segments ij having P (wij = 0 | y) > c . Fuzzy boundaries based on wij : use the P (wij = 0 | y) values themselves as the BMVs. Reilly (2001) showed is estimable even under a noninformative prior. MCMC sampling of , , , , and W can proceed by a tuned mixture of Gibbs and Metropolis steps. Try it with simulated data, arising from 0 = 1, 1 = -2, 0 = -1, and = 30. Bayesian Areal Wombling for Geographic Boundary Analysis p. 14/3 Alternative: Modeling adjacency Crisp boundaries based on wij : those segments ij having P (wij = 0 | y) > c . Fuzzy boundaries based on wij : use the P (wij = 0 | y) values themselves as the BMVs. Reilly (2001) showed is estimable even under a noninformative prior. MCMC sampling of , , , , and W can proceed by a tuned mixture of Gibbs and Metropolis steps. Try it with simulated data, arising from 0 = 1, 1 = -2, 0 = -1, and = 30. The simulation of is facilitated by WinBUGS, and log Ei 's are borrowed from a Minnesota breast cancer late detection data set. Bayesian Areal Wombling for Geographic Boundary Analysis p. 14/3 Example: Simulated data Left: Map of simulated "true" boundaries (1 - wij ), where thick dark lines indicate boundaries and thin blue lines indicate adjacency between two regions. Bayesian Areal Wombling for Geographic Boundary Analysis p. 15/3 Example: Simulated data Left: Map of simulated "true" boundaries (1 - wij ), where thick dark lines indicate boundaries and thin blue lines indicate adjacency between two regions. Right: Map of simulated "true" i on a blue color scale. Bayesian Areal Wombling for Geographic Boundary Analysis p. 15/3 Example: Simulated data Left: Map of simulated "true" boundaries (1 - wij ), where thick dark lines indicate boundaries and thin blue lines indicate adjacency between two regions. Right: Map of simulated "true" i on a blue color scale. Note: Most of the boundaries in the left panel are preserved in the right panel! Bayesian Areal Wombling for Geographic Boundary Analysis p. 15/3 Example: Simulated data Left: Map of posterior mean of 1 - pij with corresponding boundaries shaded in color. Note: The majority of these lines match with those in L panel of previous figure! Bayesian Areal Wombling for Geographic Boundary Analysis p. 16/3 Example: Simulated data Left: Map of posterior mean of 1 - pij with corresponding boundaries shaded in color. Note: The majority of these lines match with those in L panel of previous figure! Right: Map of posterior means of i on blue color scale. Note: Overall spatial pattern remains, but with smoothing of the i among neighbors. Bayesian Areal Wombling for Geographic Boundary Analysis p. 16/3 Extension: Boundary Adjacency The previous approaches (especially those based on ij ) tend to create networks of disconnected boundary segments. We would prefer an approach that drew continuous boundaries across the map. Bayesian Areal Wombling for Geographic Boundary Analysis p. 17/3 Extension: Boundary Adjacency The previous approaches (especially those based on ij ) tend to create networks of disconnected boundary segments. We would prefer an approach that drew continuous boundaries across the map. That is, given that a segment is part of the boundary, we'd like our model to favor including neighboring segments in the boundary as well. Bayesian Areal Wombling for Geographic Boundary Analysis p. 17/3 Extension: Boundary Adjacency The previous approaches (especially those based on ij ) tend to create networks of disconnected boundary segments. We would prefer an approach drew that continuous boundaries across the map. That is, given that a segment is part of the boundary, we'd like our model to favor including neighboring segments in the boundary as well. But the CAR model is ideal for this type of modeling! We simply need to define a second CAR model on the boundary segment space, in addition to the one we already have on the areal unit space. Bayesian Areal Wombling for Geographic Boundary Analysis p. 17/3 Extension: Boundary Adjacency The previous approaches (especially those based on ij ) tend to create networks of disconnected boundary segments. We would prefer an approach that drew continuous boundaries across the map. That is, given that a segment is part of the boundary, we'd like our model to favor including neighboring segments in the boundary as well. But the CAR model is ideal for this type of modeling! We simply need to define a second CAR model on the boundary segment space, in addition to the one we already have on the areal unit space. That is, if W is the N N (random) adjacency matrix for the counties, now we also have W , an Nadj Nadj (fixed) adjacency matrix for the boundary segments, where Nadj is the total number of unique county adjacencies. Bayesian Areal Wombling for Geographic Boundary Analysis p. 17/3 New Approach: 2-Level CAR That is, we need to expand our logit model to log pij 1 - pij = z + ij , ij where CAR(, W ) and W is a 0-1 adjacency matrix on the boundary segment space, with adjacency defined by the map (fixed; no covariates this time). Bayesian Areal Wombling for Geographic Boundary Analysis p. 18/3 New Approach: 2-Level CAR That is, we need to expand our logit model to log pij 1 - pij = z + ij , ij where CAR(, W ) and W is a 0-1 adjacency matrix on the boundary segment space, with adjacency defined by the map (fixed; no covariates this time). Boundaries may again be obtained from posterior summarization of the ij , the pij , or the wij . Bayesian Areal Wombling for Geographic Boundary Analysis p. 18/3 New Approach: 2-Level CAR That is, we need to expand our logit model to log pij 1 - pij = z + ij , ij where CAR(, W ) and W is a 0-1 adjacency matrix on the boundary segment space, with adjacency defined by the map (fixed; no covariates this time). Boundaries may again be obtained from posterior summarization of the ij , the pij , or the wij . To check, we generate data from a 4 4 "template" having "true boundary" separating 6 regions (the 4 in the bottom row and the middle two in the 3rd row) from the rest... Bayesian Areal Wombling for Geographic Boundary Analysis p. 18/3 New Approach: 2-Level CAR Raw Data 6 6 L&C, Pr(delta_ij>c|data) [-2.17,-1.51) [-1.51,-0.85) [-0.85,-0.19) [-0.19,0.47) [0.47,1.13) [1.13,1.79] [0.06,0.75] (0.75,0.94] 5 4 3 2 1 1 2 3 4 5 6 7 8 1 1 2 3 4 5 2 3 4 5 6 7 8 Left: Map of a simulated data set from our model. Bayesian Areal Wombling for Geographic Boundary Analysis p. 19/3 New Approach: 2-Level CAR Raw Data 6 6 L&C, Pr(delta_ij>c|data) [-2.17,-1.51) [-1.51,-0.85) [-0.85,-0.19) [-0.19,0.47) [0.47,1.13) [1.13,1.79] [0.06,0.75] (0.75,0.94] 5 4 3 2 1 1 2 3 4 5 6 7 8 1 1 2 3 4 5 2 3 4 5 6 7 8 Left: Map of a simulated data set from our model. Right: Posterior probability that ij exceeds the cutoff c, LC method (nonrandom adjacency matrix W ). Bayesian Areal Wombling for Geographic Boundary Analysis p. 19/3 New Approach: 2-Level CAR Raw Data 6 6 L&C, Pr(delta_ij>c|data) [-2.17,-1.51) [-1.51,-0.85) [-0.85,-0.19) [-0.19,0.47) [0.47,1.13) [1.13,1.79] [0.06,0.75] (0.75,0.94] 5 4 3 2 1 1 2 3 4 5 6 7 8 1 1 2 3 4 5 2 3 4 5 6 7 8 Left: Map of a simulated data set from our model. Right: Posterior probability that ij exceeds the cutoff c, LC method (nonrandom adjacency matrix W ). Note that there are six "true" boundary segments; LC finds only 3 of them. It is badly fooled by the surprisingly low values in the northeast corner and the surprisingly high value in the 3rd row, last column. Bayesian Areal Wombling for Geographic Boundary Analysis p. 19/3 Results: 2-Level CAR CAR2, Pr(delta_ij>c|data) 6 6 CAR2, post.mean of (1-pij) [0.07,0.82] (0.82,0.97] [0.12,0.17) [0.17,0.21) [0.21,0.25) [0.25,0.29) [0.29,0.34) [0.34,0.38] 5 4 3 2 1 1 2 3 4 5 6 7 8 1 1 2 3 4 5 2 3 4 5 6 7 8 Left: Posterior probability that ij exceeds the cutoff c (fuzzy boundaries), 2-Level CAR (CAR2). Bayesian Areal Wombling for Geographic Boundary Analysis p. 20/3 Results: 2-Level CAR CAR2, Pr(delta_ij>c|data) 6 6 CAR2, post.mean of (1-pij) [0.07,0.82] (0.82,0.97] [0.12,0.17) [0.17,0.21) [0.21,0.25) [0.25,0.29) [0.29,0.34) [0.34,0.38] 5 4 3 2 1 1 2 3 4 5 6 7 8 1 1 2 3 4 5 2 3 4 5 6 7 8 Left: Posterior probability that ij exceeds the cutoff c (fuzzy boundaries), 2-Level CAR (CAR2). Right: Posterior mean of 1 - pij , 2-Level CAR. Bayesian Areal Wombling for Geographic Boundary Analysis p. 20/3 Results: 2-Level CAR CAR2, Pr(delta_ij>c|data) 6 6 CAR2, post.mean of (1-pij) [0.07,0.82] (0.82,0.97] [0.12,0.17) [0.17,0.21) [0.21,0.25) [0.25,0.29) [0.29,0.34) [0.34,0.38] 5 4 3 2 1 1 2 3 4 5 6 7 8 1 1 2 3 4 5 2 3 4 5 6 7 8 Left: Posterior probability that ij exceeds the cutoff c (fuzzy boundaries), 2-Level CAR (CAR2). Right: Posterior mean of 1 - pij , 2-Level CAR. When applied to the ij 's, the CAR2 method performs no better than LC. But when applied to the pij 's, the method now correctly finds all six boundary segments. Bayesian Areal Wombling for Geographic Boundary Analysis p. 20/3 Current Work Compare methods based on ij and wij by simulating the average probability that they correctly classify each potential boundary segment Bayesian Areal Wombling for Geographic Boundary Analysis p. 21/3 Current Work Compare methods based on ij and wij by simulating the average probability that they correctly classify each potential boundary segment Various remedies for handling "islands" (regions with no neighbors) when modeling adjacency Bayesian Areal Wombling for Geographic Boundary Analysis p. 21/3 Current Work Compare methods based on ij and wij by simulating the average probability that they correctly classify each potential boundary segment Various remedies for handling "islands" (regions with no neighbors) when modeling adjacency Investigate L1 (absolute difference) CARs, and sensitivity to the choice of priors p(i ) that control the effect of the covariate data Zij Bayesian Areal Wombling for Geographic Boundary Analysis p. 21/3 Current Work Compare methods based on ij and wij by simulating the average probability that they correctly classify each potential boundary segment Various remedies for handling "islands" (regions with no neighbors) when modeling adjacency Investigate L1 (absolute difference) CARs, and sensitivity to the choice of priors p(i ) that control the effect of the covariate data Zij Try to increase the impact of response data Yi on the wombled boundaries (relative to the covariates Zij ) while retaining boundary connectedness Bayesian Areal Wombling for Geographic Boundary Analysis p. 21/3 Current Work Compare methods based on ij and wij by simulating the average probability that they correctly classify each potential boundary segment Various remedies for handling "islands" (regions with no neighbors) when modeling adjacency Investigate L1 (absolute difference) CARs, and sensitivity to the choice of priors p(i ) that control the effect of the covariate data Zij Try to increase the impact of response data Yi on the wombled boundaries (relative to the covariates Zij ) while retaining boundary connectedness by eliminating the CAR(, W ) model and the i 's altogether (but retaining the CAR(, W ) and the ij ) Bayesian Areal Wombling for Geographic Boundary Analysis p. 21/3 Current Work Compare methods based on ij and wij by simulating the average probability that they correctly classify each potential boundary segment Various remedies for handling "islands" (regions with no neighbors) when modeling adjacency Investigate L1 (absolute difference) CARs, and sensitivity to the choice of priors p(i ) that control the effect of the covariate data Zij Try to increase the impact of response data Yi on the wombled boundaries (relative to the covariates Zij ) while retaining boundary connectedness by eliminating the CAR(, W ) model and the i 's altogether (but retaining the CAR(, W ) and the ij ) by retaining both CAR models, but fitting them simultaneously, rather than hierarchically Bayesian Areal Wombling for Geographic Boundary Analysis p. 21/3 Connected, Yi-dominated boundaries Eliminating the CAR(, W ) model and the i 's: Suppose we think of the original data Yi as normal. Then the differences Dij = Yi - Yj are also normal (note differences, not absolute differences here). Bayesian Areal Wombling for Geographic Boundary Analysis p. 22/3 Connected, Yi-dominated boundaries Eliminating the CAR(, W ) model and the i 's: Suppose we think of the original data Yi as normal. Then the differences Dij = Yi - Yj are also normal (note differences, not absolute differences here). Suppose Dij N (ij , 1/e ), where ij = 0 + zij 1 + ij . Let zij = xi - xj (again, difference not absolute difference here), and we again let CAR(, W ). Bayesian Areal Wombling for Geographic Boundary Analysis p. 22/3 Connected, Yi-dominated boundaries Eliminating the CAR(, W ) model and the i 's: Suppose we think of the original data Yi as normal. Then the differences Dij = Yi - Yj are also normal (note differences, not absolute differences here). Suppose Dij N (ij , 1/e ), where ij = 0 + zij 1 + ij . Let zij = xi - xj (again, difference not absolute difference here), and we again let CAR(, W ). This model eliminates the hard-to-estimate Wij (Bernoulli) parameters, and retains only the "second" CAR model, which captures the similarity of neighboring boundary segments on the map. Bayesian Areal Wombling for Geographic Boundary Analysis p. 22/3 Connected, Yi-dominated boundaries Eliminating the CAR(, W ) model and the i 's: Suppose we think of the original data Yi as normal. Then the differences Dij = Yi - Yj are also normal (note differences, not absolute differences here). Suppose Dij N (ij , 1/e ), where ij = 0 + zij 1 + ij . Let zij = xi - xj (again, difference not absolute difference here), and we again let CAR(, W ). This model eliminates the hard-to-estimate Wij (Bernoulli) parameters, and retains only the "second" CAR model, which captures the similarity of neighboring boundary segments on the map. This model should deliver ij -based wombled boundaries that are more connected than before Bayesian Areal Wombling for Geographic Boundary Analysis p. 22/3 Connected, Yi-dominated boundaries Simultaneous fitting of the two CAR models: Suppose we replace the Poisson mean structure with log i = log Ei + x + i + i , i where CAR(, W ) and CAR(, W ) as before. Bayesian Areal Wombling for Geographic Boundary Analysis p. 23/3 Connected, Yi-dominated boundaries Simultaneous fitting of the two CAR models: Suppose we replace the Poisson mean structure with log i = log Ei + x + i + i , i where CAR(, W ) and CAR(, W ) as before. Now i , the average of the edge effects for those edges that comprise region i, contributes directly to the mean structure (instead of to the variance structure via W ). The ij capture signed agreement since: Bayesian Areal Wombling for Geographic Boundary Analysis p. 23/3 Connected, Yi-dominated boundaries Simultaneous fitting of the two CAR models: Suppose we replace the Poisson mean structure with log i = log Ei + x + i + i , i where CAR(, W ) and CAR(, W ) as before. Now i , the average of the edge effects for those edges that comprise region i, contributes directly to the mean structure (instead of to the variance structure via W ). The ij capture signed agreement since: ij = 0 when Yi and Yj are both larger or both smaller than expected Bayesian Areal Wombling for Geographic Boundary Analysis p. 23/3 Connected, Yi-dominated boundaries Simultaneous fitting of the two CAR models: Suppose we replace the Poisson mean structure with log i = log Ei + x + i + i , i where CAR(, W ) and CAR(, W ) as before. Now i , the average of the edge effects for those edges that comprise region i, contributes directly to the mean structure (instead of to the variance structure via W ). The ij capture signed agreement since: ij = 0 when Yi and Yj are both larger or both smaller than expected ij 0 when one o...

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Minnesota - BIOSTAT - 8472
Example using R: Heart Valves StudyGoal: Show that the thrombogenicity rate (TR) is less than two times the objective performance criterionR and WinBUGS Examples p. 1/4Example using R: Heart Valves StudyGoal: Show that the thrombogenicity rate
Minnesota - BIOSTAT - 8472
Spatial data analysis with spBayesExisting software for point-level hierarchical spatial modeling: WinBUGS/BRugs and the geoR package Limitations of WinBUGS for point-level models: Poor with matrix computations infeasible for even a moderate number
Minnesota - BIOSTAT - 8472
Spatial Biostatistics PubH 8472 Instructor: Office: fax: e-mail: course website: Class Meetings: Office Hours: Dr. Brad Carlin Mayo Building, Room A427; phone 624-6646 626-0660 brad@biostat.umn.edu www.biostat.umn.edu/brad/ph8472.html Tu Th 9:45 11:
Minnesota - BIOSTAT - 8472
%!PS-Adobe-2.0 %Creator: dvipsk 5.58f Copyright 1986, 1994 Radical Eye Software %Title: syll.dvi %Pages: 6 %PageOrder: Ascend %BoundingBox: 0 0 612 792 %EndComments %DVIPSCommandLine: /usr/local/TeX/bin/dvi2ps -o syll.ps syll.dvi %DVIPSParameters: dp
Minnesota - BIOSTAT - 8472
map: 29 grid1 1grid2 2grid3 3grid4 4grid5 5grid6 6grid7 7grid8 8grid9 9grid10 10grid11 11grid12 12grid13 13grid14 14grid15 15grid16 16grid17 17grid18 18grid19 19grid20 20grid21 21grid22 22grid23 23grid24 24grid25 25grid26 2
Columbia - ATS - 2107
Journal of Business Research 60 (2007) 285 295Interfirm behavior and goal alignment in relational exchangesAndrew T. Stephen a, Leonard V. Coote baColumbia University, Graduate School of Business, Uris Hall, 3022 Broadway, Room 311, New York,
Washington - ENG - 198
Eng198C/Anth204 Winter 2006 Instructor: Megan Styles Assignment 3.2 Interview 1 Analysis Your final paper requires you to analyze the results of your life and health history interviews in light of concepts discussed in class. For this assignment, you
Sveriges lantbruksuniversitet - ECON - 306
Student Questionnaire Form Econ 387: Spring 2006 David Andolfatto Instructions: Feel free to provide feedback on this course using this form at any time during the semester. You do not have to put your name on the form. Once you fill it out, print it
Sveriges lantbruksuniversitet - ECON - 306
Econ 387: Midterm 1 February 9, 2006 D. Andolfatto Name Instructions. Do not begin the exam until you are instructed to do so. Read the exam over carefully and raise your hand if you need clarification. In answering the questions, limit your answers
Sveriges lantbruksuniversitet - ECON - 306
Econ 387: Midterm 1 February 9, 2006 Answer Key [1] [10 Marks]. What is the definition of an indifference curve? Why are indifference curves an important component of macroeconomic analysis? (Provide two reasons). An indifference curve is defined as
Sveriges lantbruksuniversitet - ECON - 306
Econ 387March 9, 2006 Name:_Student Number:_ Instructions. Do not begin the exam until you are instructed to do so. Read the exam over carefully and raise your hand if you need clarification. In answering the questions, limit your answers to the spa
Sveriges lantbruksuniversitet - ECON - 306
Econ 387March 9, 2006 [1] [10 Marks]. What is the definition of an indifference curve? Why are indifference curves an important component of macroeconomic analysis? (Provide two reasons). An indifference curve is defined as the set of all commodity
Sveriges lantbruksuniversitet - ECON - 306
A Basic Neoclassical Business Cycle Model with Heterogeneous AgentsDavid Andolfatto January 18, 20061IntroductionChapter 2 in the textbook models an economy consisting of many individuals who are literally assumed to be identical; this is the
Sveriges lantbruksuniversitet - ECON - 306
Econ 387: Assignment 1David Andolfatto January 2006Consider an economy populated by a representative agent with preferences for consumption and leisure given by the expected utility function: E[U (c, l)] = h(l) + E[c], where &gt; 0 is a parameter, h
Sveriges lantbruksuniversitet - ECON - 306
Econ 387: Assignment 2David Andolfatto January 2006This question constitutes an application of the heterogeneous agents model (available on the course web page). Consider an economy consisting of people with preferences for consumption and leisure
Sveriges lantbruksuniversitet - ECON - 306
Econ 387 Spring 1998 Assignment 3 1. Consider an economy consisting of N individuals with preferences for time-dated consumption given by: u(c1i , c2i ) = ln(c1i ) + i ln(c2i ) for i = 1, 2, ., N. Each individual has a time-dated endowment (y1i , y2
Sveriges lantbruksuniversitet - ECON - 306
Econ 387: Spring 2006 Assignment 4: Term Structure of Interest Rates 1. Consider a closed populated by a representative agent with preferences defined over time-dated consumption (c1 , c2 , c3 ). These preferences are given by: U (c1 , c2 , c3 ) = ln
Sveriges lantbruksuniversitet - ECON - 809
Search Models of UnemploymentDavid Andolfatto March 20061IntroductionTo the average person (perhaps even the average economist), unemployment is often equated to a state of involuntary idleness. Such a view, however, appears inconsistent with
Sveriges lantbruksuniversitet - ECON - 809
Econ 809: Assignment 1January 20061Part 1On Robert Shimer's webpage, http:/home.uchicago.edu/~shimer/data/mmm/, you will find data on the job-finding rate pt , and the vacancy-unemployment ratio t . Use this data to perform a `Solow residual'
Sveriges lantbruksuniversitet - ECON - 809
Econ 809: Assignment 1 Answer Key Consider an aggregate matching technology with the following functional form: mt = ext vt u1- . t This may alternatively be specified as pt = ext , where pt mt /ut denotes t the job-finding rate and t vt /ut deno
Sveriges lantbruksuniversitet - ECON - 809
Econ 809 Spring 2006 Assignment 2 The due date for this assignment is Tuesday, February 21. 1. In class, we developed a baseline Pissarides-style labor market search model. The theory essentially boiled down to two restrictions: one describing the su
Sveriges lantbruksuniversitet - ECON - 809
Econ 809: Assignment 3 Spring 2006 David Andolfatto 1. Consider an economy consisting of 2-period-lived overlapping generations (with an initial old generation that lives for one period only). Let us restrict attention to stationary allocations. A re
Sveriges lantbruksuniversitet - ECON - 809
Econ 809 Spring 2006 Assignment 1. Time is discrete and the horizon is infinite; t = 0, 1, ., . Each period is divided into two subperiods; stage 1 and stage 2 (day and night). There is a unit mass of infinitely-lived ex ante identical agents i [0,
Sveriges lantbruksuniversitet - ECON - 809
Real Business Cycle Models: Past, Present, and FutureSergio Rebelo March 2005Abstract In this paper I review the contribution of real business cycles models to our understanding of economic fluctuations, and discuss open issues in business cycle r
Sveriges lantbruksuniversitet - ECON - 809
Money and Credit in Quasi-linear EnvironmentsDavid Andolfatto Simon Fraser University March 2006Abstract I consider a version of the quasi-linear environment suggested by Lagos and Wright (2005). In the first part of these notes, I lay out the bas
Sveriges lantbruksuniversitet - ECON - 809
The Economics of PaymentsEd Nosal and Guillaume Rocheteau January 20, 200611IntroductionEconomics is all about exchange, but exchange need not be seamless. How else can one explain the existence of the myriad assets and institutions- domesti
Sveriges lantbruksuniversitet - ECON - 809
Notes on Exchange Rate Volatility in an Equilibrium Asset Pricing Model Manuelli and Peck (IER, 1990)1ModelTime is discrete and the horizon is infinite; t = 1, 2, ., . There are two economies, each of which are populated by a sequence of two-pe
Sveriges lantbruksuniversitet - ECON - 809
Dynamic Taxation, Private Information and MoneyChristopher Waller University of Notre Dame March 4, 2006 VERY PRELIMINARYAbstract The objective of this paper is to study optimal .scal and monetary policy in a dynamic Mirrlees model where the frict
Sveriges lantbruksuniversitet - ECON - 809
Bank Runs Under Optimal Banking StructuresDavid Andolfatto Simon Fraser University Ed Nosal Federal Reserve Bank of ClevelandNeil Wallace Pennsylvania State University November 17, 20051 2Introduction Physical EnvironmentThe economy consists
Sveriges lantbruksuniversitet - ECON - 305
1?ymonoce eht gnitcapmi morf 'skcohs ytivitcudorp` tneverp wohemos ot tnemnrevog eht rof )elbarised e b ti dluow ,os fi dna( elbisaef eb ti dluoW ?etautcufl ot raeppa ytivitcudorp seod ,weiv ruoy ni ,yhW .]skraM 01[ .2.selbairav suonegodne fo tes
Sveriges lantbruksuniversitet - ECON - 305
Econ 305: Intermediate Macroeconomic Theory October 4, 2004 D. Andolfatto Name Instructions. Please limit your answer to the space provided below each question. Do not write on the back of the exam paper (it will not be graded). Pen or pencil is fine
Sveriges lantbruksuniversitet - ECON - 305
Econ 305: Midterm1Answer KeyOctober 5, 2005 D. Andolfatto Name Instructions. Please write neatly and label all diagrams clearly. Limit your answers to the space provided below each question-do not write your answers on the back of the exam or in t
Sveriges lantbruksuniversitet - ECON - 305
1.ymonoce na rof swen dab ylraelc si ticfied tnuocca tnerruc eht ni esaercni nA )e(.noitisop tnuocca tnerruc sti no tceffe on evah ot ylekil si ytivitcudorp ot kcohs )yraropmet tub( esrevda na ,ymonoce nepo llams a roF )d(.dnamed remusnoc etalu
Sveriges lantbruksuniversitet - ECON - 305
Econ 305: Intermediate Macroeconomic Theory November, 2004 D. Andolfatto Name Instructions. Please limit your answer to the space provided below each question. Do not write on the back of the exam paper (it will not be marked). Either print or write
Sveriges lantbruksuniversitet - ECON - 305
Econ 305: Midterm1 (Answer Key) November 2, 2006 D. Andolfatto Name[1] [10 Marks]. Consider a closed economy where output is in entirely in the form of a nonstorable consumption good. Assume that output y is generated entirely by labor (and that ho
Sveriges lantbruksuniversitet - ECON - 305
.nialpxE ?yroeht htiw tnetsisnoc tcaf cisab siht sI .dnert elbinrecsid on nwohs sah rotces tekram eht ot etoved elpoe p taht emit fo tnuoma eht ,sraey 001 tsal eht revo ylidaets gnisaercni neeb evah adanaC ni segaw laer taht tcaf eht etipseD .]skraM
Sveriges lantbruksuniversitet - ECON - 305
Econ 305: Final Exam December 2004 D. Andolfatto Name Instructions. Please limit your answer to the space provided below each question. Label all diagrams clearly. If a question asks you to answer in words only, then do not use any math, symbols or d
Sveriges lantbruksuniversitet - ECON - 810
Notes on Contracts and MoneyD. Andolfatto May 5, 20081A Standard Principal-Agent ProblemA risk-neutral principal hires a risk-averse agent. The agent applies effort n; which generates output y {yl , yh } , 0 &lt; yl &lt; yh &lt; . Let (n) = Pr [y = yh
Sveriges lantbruksuniversitet - ECON - 810
Optimal Debt ContractsDavid Andolfatto February 20081IntroductionAs an introduction, you should read &quot;Why is There Debt,&quot; by Lacker (1991). As Lacker notes, the striking feature of a debt contract is that debt payments are fixed over a wide ra
Sveriges lantbruksuniversitet - ECON - 810
Lecture Notes The Role of Demandable Debt in Structuring Optimal Banking Arrangements Calomiris and Kahn (AER, 1991)1Basic ModelAs usual, there are two agents; in this case, labelled a banker and depositor. The banker has no wealth, but has an
Sveriges lantbruksuniversitet - ECON - 810
Notes on Diamond and Dybvig (JPE, 1983) David Andolfatto February 20081BasicsThere are N &gt; 1 agents (a finite integer). Each agent has an endowment y &gt; 0. There are two periods, t = 1, 2 and agents have preferences for `current' and `future' co
Sveriges lantbruksuniversitet - ECON - 810
Notes on Jacklin (1987) David Andolfatto February 20081Basic Diamond-Dybvig (Review)There are N &gt; 1 agents (a finite integer). Each agent has an endowment y &gt; 0. There are two periods, t = 1, 2 and agents have preferences for `current' and `fut
Sveriges lantbruksuniversitet - ECON - 810
.ytniatrecnu etagergga on si erehT .tnega laudividni na fo evitcepsrep eht morf ytilibaborp a sa deweiv si retemarap ehT .rennam siht ni detacoler si taht )dnalsi hcae no( noitalupop eht fo noitcarf eht etonedteL . noitacol 'rehto eht` ot noitaco
Georgia Tech - CHEM - 1315
III Aromatic CompoundsAromatic Compounds: Compounds that resemble benzene in structure andchemical behavior (terms comes from fragrant odors)Benzene:- Cyclic Compound - Six-Membered Ring - ONLY Six Hydrogens - Six Carbons - Three Double Bonds
Columbia - AM - 2993
ABHINANDAN MAJUMDARB2, 500 Riverside Drive New York 10027, NY, USA Phone: +1-646-509-5767(M) Email: am2993@columbia.edu http:/www.columbia.edu/~am2993Education Master of Science in Computer Engineering at Columbia University (Graduation Date: D
Allan Hancock College - ENGN - 4528
Image Processing Toolbox. Version 3.2 (R13) 28-Jun-2002 Release information. images/Readme - Display information about current and previous versions. Image display. colorbar - Display colorbar (MATLAB Toolbox). getimage - Get image data from axes. im
George Mason - ECE - 499
Catching up Homework from last week is due Feb 12th. If you are on time, you should have (1) thought about your circuit and found a good opamp for it; (2) downloaded a layout program (PCB123, or ExpressPCB). Wednesday, Feb 7th, 2pm: Layout Discuss
George Mason - ECE - 499
Announcements Newly available: webct41.gmu.edu What is there? Files; messages; questions &amp; answers. Next Monday, 3:45pm, Chem safety training.Schmitt triggerHow to design a simple circuit Read up on your problem (internet) Use application no
George Mason - ECE - 499
Drug Delivery Systemscontainer + drugbodyDefinition: drug delivery systems Biomaterials used to release drugs in the body, in a controlled manner. Control of timing and target.http:/www.devicelink.com/mpb/archive/97/11/9711b34b.jpg Convent
George Mason - ECE - 499
Lab sessions from March 7 to May 1stScheduling, project demos, lab etiquetteth2 labs/experiment, 4 groupsMar 7 and Mar 21 Neurot FSR glove ECG Accelerometer/EMG Original project 1 2 3 4 Mar 28 and Apr 4 2 1 4 3 Apr 11 and Apr 18 3 4 1 2 Apr 25
George Mason - ECE - 499
Biomedical SensorsInstrumentation System Sensor characteristics Physical SensorsAnnouncements On Wednesday we continue the two groups (1:30pm and 3pm). You are responsible for running the experiments! Webct has a suggested format for lab report
George Mason - ECE - 499
Biomedical SensorsInstrumentation System Sensor characteristics Physical SensorsLast lecture before midterm. Exam will be emailed to you on Wednesday, March 7th.Announcements On Wednesday we continue the two groups (1:30pm and 3pm). I won't an
George Mason - ECE - 499
Biomedical SensorsFrom last class: Performance measurement Transducers Kinds of sensors pO2 (electrochemical sensor)Electrode Electrolyte InterfaceElectrode C eeC+ : Cation Electrolyte (neutral charge) C+, A- in solution Current flow C C AAA
George Mason - ECE - 499
Biomedical SensorsFrom last class: Performance measurement Transducers Kinds of sensors pO2 (electrochemical sensor)Electrode Electrolyte InterfaceElectrode C eeC+ : Cation Electrolyte (neutral charge) C+, A- in solution Current flow C C C+
George Mason - ECE - 499
Biomechanics What is it? Application of Mechanical Engineering principles to living systems. Design of orthopaedic devices Treatment of skeletal diseases Study of damage and repair of the skeletonBones Deformable structures Bone tissue: stru
George Mason - ECE - 499
George Mason - ECE - 499
ECE 499HOMEWORK #1Due 1/29/07 at 3pm.1. You measure, in a patient, 12 R waves in 7.3 seconds. What is the heart rate? 2. Consider the same conditions as in question 1. What is the patient's cardiac output for a stroke volume of 75ml? 3. Explain
George Mason - ECE - 499
This is one of 12 activities suggested by the LabView tutorial from National Instruments. By now you should know most of these blocks (VIs). Work in groups of two and try to understand the idea behind the activity, while following their instructions.
George Mason - ECE - 499
ECE 499 Introduction to BioengineeringJan 22nd, 2007 May 16th, 2007 Nathalia Peixoto npeixoto@gmu.edu 703 993 1567 Room 211, ST II. What is this course?The idea: present topics in Bioengineering. Theory and hands-on. Labs may not go in parall
George Mason - ECE - 499
Homeostasis Systems Physiology, part 2Homeostasis Cardiac physiology basics And the respiratory system The body can survive under diverse environmental conditions. However, the internal environment is maintained within a narrow range of temperature