to Introduction Biomechanical Systems
Course Syllabus
Fall 2009
Course overview: Welcome to Introduction to Biomechanical Systems, an elective in the MEM biomechanics concentration. The course is designed to provide an overview of biological applications of mechanical engineering. We will introduce you to varied fields of biomechanical engineering, hopefully piquing your interest in particular area (or areas) and inspiring you to pursue further coursework or research in that area. With your help, this course will be a great learning experience by exposing you to a breadth of interesting material and hopefully challenging you to think about nontraditional applications of mechanical engineering. Catalog description An overview of the application of mechanical engineering to biological systems. Covers basic anatomy and physiology; tissue, joint, cell, and protein mechanics; joint kinematics; biofluid mechanics; biothermodynamics; biotransport; biomimetic controls; and biomanufacturing. Credits: 3.00 Instructors: Name Dr. Alisa Clyne Class Sessions: Lecture: Prerequisites: MATH 200, PHYS 101, CHEM 102, BIO 141 Office AEL 170C Phone [phone] Email [e-mail] Office Hrs
Tuesday and Thursday
11:00 AM 12:20 PM (Curtis 162)
The class format will vary among presentation of new material, demonstration, lab, case study, research paper discussion, or guest lecture by an expert in the topic of the day. Each weeks assignment will be at least partially derived from a hands-on class activity. Course Materials and Website: Optional Textbook: Ethier and Simmons. Introductory Biomechanics: From Cells to Organisms You may also find it helpful to purchase a quantitative physiology book such as Berne and Levy Physiology. There are copies of the course textbook, an anatomy book, and a physiology book on reserve in the Hagerty Library. Blackboard Website: The Blackboard website will be the primary means of distributing material and communicating information for the course. Check it regularly. Materials on the website are for the personal educational use of students only.
Grading: Your grade in this course will be determined based on your class participation, assignments, and final exam as outlined in the table below: Weekly Assignments 60% Final Paper 35% Class participation 5% Expectations for grading: Assignments: There will be 7 assignments. The assignment format will vary and may be a lab report, a problem set, a research paper analysis, or some combination of the three. Partial credit will be given, therefore thorough explanations are encouraged. Assignments are due at the beginning of class no late assignments will be accepted, but your lowest assignment score will be omitted. If you will be late or absent from class, you must email your assignment as a PDF to [e-mail] by 11:00 AM on the day it is due. There are no exceptions to this rule. Class participation: Both lecture and lab/demonstration/discussion are active learning sessions, therefore the professor and students are all expected to participate actively. You may be called upon to answer questions or solve problems, therefore it is highly recommended that you do the assigned reading prior to each class. Final paper: The final paper will be due December 7th. This paper can be written about any topic in biomechanical engineering. The paper is a maximum of 10 pages, doublespaced, 12 point Times New Roman, with 1 margins. The paper cite must at least 5 research journal papers. Academic Honesty This course will strictly adhere to the Drexel University policy on academic conduct. For details, please refer to http://www.drexel.edu/provost/policies/academic_dishonesty.asp. Some specifics of how the academic policy applies to this course are given below. This list is not comprehensive, so if in doubt, please ask before doing. What is the policy on exams? Exams are representative of your own work, therefore you may not receive help from any students or non-approved sources during the exam. May we work together on the assignments? We encourage students to discuss and work together on assignments. However, the assignment you turn in must be solely your own work. May we use the Internet? You may use select valid Internet sources, such as PubMed and Web of Science, to locate journal articles. Be sure to check and cite your sources.
Course Objectives: Students completing Introduction to Biomechanical Engineering will be able to: 1. Explain how physiology is governed by mechanics on different size scales, from the human body to cells to proteins. 2. Classify physiologic systems in terms of governing principles. 3. Solve mechanics, kinematics, fluid mechanics, transport, and controls problems applied to biological systems. 4. Understand and speak the language of biology. 5. Design, conduct, and interpret basic experiments in biomechanical engineering. 6. Analyze research papers in varied fields of biomechanical engineering. Topics: 1. Basic anatomy and physiology 2. Tissue, joint, cell, and protein mechanics 3. Joint kinematics 4. Bio-fluid mechanics 5. Bio-nanotechnology 6. Biotransport 7. Biomimetic controls 8. Biomanufacturing Honors Project: Students who wish to receive honors credit for MEM 380 can write a 10 page mock grant application on a topic covered in the course. See Dr. Clyne for details. While every attempt has been made to make this syllabus complete and accurate, the professor reserves the right to change the policies or schedule as necessary. Students will be notified of any changes in a timely manner.
Course Schedule:
Week
1
Date
Sept 22
Subject
Introduction
Reading
Online or reserve anatomy book
Papers* Papers* Ethier: Ch. 3, 4 Papers* Ethier: Ch. 7 Papers* Papers*
Lecture
Clyne Clyne Hirsch Sun Clyne Clyne Clyne Clyne Kresh Clyne Clyne Clyne Clyne Noh Clyne Siegler Tangorra Song Clyne Moore Domzalski
Anatomy and cell biology Sept 24 overview Sept 29 Human Anatomy Oct 1 Oct 6 Oct 8 Oct 13 Oct 15 Oct 20 Oct 22 Oct 27 Oct 29 Nov 3 Nov 5 Nov 10 Nov 12 Nov 17 Nov 19 Nov 24 Dec 1 Dec 3 Dec 7 Tissue Engineering Bio-nanotechnology Nano: good or bad Cardiovascular fluid mechanics Exercise laboratory Cardiovascular device design Respiratory fluid mechanics Biotransport Cell membranes Paper workshop Lab-on-a-chip Bone and muscle mechanics Joint kinematics Biocontrols Gait Cell mechanics Injury Biomechanics Bioethics Final paper due
2 3 4 5 6 7 8 9 10 11
Ethier: Ch. 9, 10
Ethier: Ch 8: p 353-69 Ch 10: p 461-78 Ethier: Ch 2 Papers*
* See Blackboard site for lecture notes, paper downloads, and assignments. 1 2 3 4 5 6 7 Assignment Anatomy and biology worksheet Nanotechnology paper Exercise laboratory Paper prewriting Biotransport laboratory Mechanics problem set Gait laboratory Date handed out 9/24/09 10/6/09 10/15/09 10/29/09 11/10/09 11/19/09 Date due 9/29/09 10/8/09 10/20/09 10/27/09 11/3/09 11/17/09 11/24/09