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Descriptions of Participants

Course: BIOE 301, Fall 2009
School: Acton School of Business
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Emanual, Ezekial Chief of Bioethics NIH Simple idea: justice requires treating everyone, everywhere in exactly the same way Justice requires no such thing. It simply requires us to treat people fairly. If rules of clinical trials require participants to receive the best care on earth, there would be no clinical trials. Marcia Angel Medical ethics has no borders What is morally right in America is morally...

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Emanual, Ezekial Chief of Bioethics NIH Simple idea: justice requires treating everyone, everywhere in exactly the same way Justice requires no such thing. It simply requires us to treat people fairly. If rules of clinical trials require participants to receive the best care on earth, there would be no clinical trials. Marcia Angel Medical ethics has no borders What is morally right in America is morally right in Africa, too International rules of medical expt. require: Volunteers in vaccine trial receive best treatment available, NOT level of care in poor country People are not guinea pigs. Research must hold human welfare above interest of society and science. If you dont, youre on a slippery slope where first humans are exploited for worthwhile purposes, then for not so worthwhile purposes. Peter Lurie Fears scientists will use poor quality of care available in Africa to do what they want You are not permitted to use subjects to collect data just because it is useful to you That is exploitation and abuse That is what Tuskegee was Scientists will withhold treatments they know will work in the name of science Will be greatest injustice in hx of medicine Tests of AZT proved there was a two-tiered standard for health care in the world One set of rules for rich people, and another for those who are poor Andrew McMichael Abhors hype Rarely discusses his vaccine work without saying it all might come to nothing First vaccine to target specific viral subtype most prevalent in East Africa Might require frequent booster shots Sarah Rowland-Jones Infectious disease specialist First vaccine to target specific viral subtype most prevalent in East Africa Might require frequent booster shots Pontiano Kaleebu We have asked Ugandans to be guinea pigs before. We have not come back to say, Here is your reward. Worried that question of whether trials can be done fairly and ethically, will overshadow science We will give people the best care we can afford. That is fair. If I could distribute anti-retroviral drugs, I would be thrilled. But, I dont see how and dont I see when. And the debate is a bit patronizing. This is not an issue of individual rights. It is a public health emergency. I never though AIDS would be in my children's futures. I have come to realize that now. And it frightens me. Edward Mbidde, Uganda Cancer Inst. Last 15 years have best Uganda has seen We have leadership, support, we are united If we need to go to work and we cannot afford a Mercedes Benz, should we refuse to ride a motorcycle? Or should we get there by the best route we have? Principles matter to us as much to us as they do to Americans. But we have been dying for a long time, and you cannot respond to death with principles. Seth Berkley You have to ask yourself what on earth the people on this planet are doing In the end only a vaccine will matter There is no incentive for companies to make vaccines Society cant get it together. These trials cost hundreds of millions of dollars. How do we pay for it? Don Francis Would be pleased if vaccine worked 1/3 of the time If his vaccine is introduced and proven effective, no other vaccines can be tested against placebo Ugandan Medical Student Would it be fair for village people to enter trial if those who became infected did not get anti-retroviral drugs...

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Acton School of Business - BIOE - 301
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