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SUNY Buffalo - PHARMACOLO - PMY406
Antipsychotic Psychopharmacology agentsSpring 2011Harvey Alan Berman, PhDHberman@buffalo.eduObjectives Describe the dopamine hypothesis of schizophrenia List the major receptors blocked by antipsychotic drugs Understand the pharmacology of the Older
SUNY Buffalo - PHARMACOLO - PMY406
Antipsychotic Psychopharmacology agentsPart IISpring 2011Harvey Alan Berman, PhDHberman@buffalo.eduSchizophreniaNeurotransmitter theories (DA, 5HT, Glutamate) Genetic Disorder of developmental Neurodegenerative disorder ViralAnatomical Findings Bra
SUNY Buffalo - PHARMACOLO - PMY406
Pharmacology of Opioid AnalgesicsSpring 2011Harvey Alan Berman, PhD, MPHDepartment of Pharmacology and Toxicology hberman@buffalo.edu 829-2658Pain An unpleasant sensory and emotional experience associated with actual or potential tissue damage Distin
SUNY Buffalo - PHARMACOLO - PMY406
Pharmacology of Selected OpiodsSpring 2011Harvey Alan Berman, PhD, MPHDepartment of Pharmacology and Toxicology hberman@buffalo.edu 829-2658Opioid classification Agonist Strong Mild-to-moderate Opioids with mixed actions Agonist-antagonist (Ag-Anta
SUNY Buffalo - PHARMACOLO - PMY406
Pharmacology of Selected OpiodsSpring 2011Harvey Alan Berman, PhD, MPHDepartment of Pharmacology and Toxicology hberman@buffalo.edu 829-2658Opioid classification Agonist Strong Mild-to-moderate Opioids with mixed actions Agonist-antagonist (Ag-Anta
SUNY Buffalo - PHARMACOLO - PMY406
LEARNING AND MEMORY,Cerebral cortex BASAL GANGLIASPEECH AND LANGUAGE. Structures believed to be important for various kinds of learning and memor y include the cerebral cortex, amygdala, hippocampus, cerebellum and basal ganglia. Areas of the left be ac
SUNY Buffalo - PHARMACOLO - PMY406
AntidepressantsPMY 406/512/516 Spring 2011Symptoms of Depression Insomnia Poor appetite, weight loss Fatigue, loss of energy Agitation Loss of interest Feelings of helplessness, worthlessness Diminished ability to think or concentrate Thoughts of death
SUNY Buffalo - PHARMACOLO - PMY406
AntidepressantsPart IIPMY 406/512/516 Spring 2011Monoamine oxidase inhibitorsTranylcypromine (Parnate) Phenelzine (Nardil)Tricyclic antidepressantsImipramine (Tofranil) Doxepin (Sinaquan) Amitriptyline (Elavil)SSRIsEscitalopram (Lexapro) Citalopra
SUNY Buffalo - PHARMACOLO - PMY406
PHARMACOLOGY OF DOPAMINE SYSTEMSJAN. 26 & 28 - CHAPTER 12, GOLAN11Dopaminergic Transmission22Dopamine Synthesis33Catecholamine Metabolism44Dopamine ReceptorsExcitatory; basal ganglia function, memory and performance5Inhibitory; decreases d
SUNY Buffalo - PHARMACOLO - PMY406
Pharmacology Of Dopamine SystemsPart ii Drug Treatment of Parkinsons DiseaseJAN. 28 - CHAPTER 12, GOLAN1PARKINSONS DISEASE (PD)PD is a neurodegenerative disorder principally of the extrapyramidal system associated with disruption of neurotransmission
SUNY Buffalo - PHARMACOLO - PMY406
Drug Addiction and Drug AbusePMY 406 / 512 / 516 Spring 2011ReadingGolan, Chapter 17 Goodman and Gilman, Chapter 23*Recommended readingVolkow and Li (2004) Drug addiction: The neurobiology of behaviour gone awry, Nat. Revs Neurosci, 5, 963-970. Hyman
SUNY Buffalo - PHARMACOLO - PMY406
PHARMACOLOGY OF GABA & GLUTAMATE SYSTEMSChap. 11Fri.GolanJan. 211OBJECTIVESUnderstand the physiology of GABAergic and glutamatergic neurotransmission. Understand how pharmacologic agents can modify GABA activity, resulting in therapeutic &/or toxic
SUNY Buffalo - PHARMACOLO - PMY406
General AnestheticsHistory - diethyl ether (1846), Chloroform (1847), nitrous oxide (1863, initially 1845), thiopental (1935), curare, halothane (1956), desflurane, sevoflurane Neurophysiological changes - unconsciousness, analgesia, inhibition of sensor
SUNY Buffalo - PHARMACOLO - PMY406
Local AnestheticsLocal anesthesia History - cocaine (Niemann 1860), procaine (Einhorn 1905), lidocaine (Lfgren 1943)Cerebral cortexPain PathwaysThe role of nerve conduction in sensory & motor function Significance of blocking nerve conduction Blockade
SUNY Buffalo - PHARMACOLO - PMY406
CNS PHARMACOLOGY IPRINCIPLES OF CNS DRUG ACTION IJAN. 19 & 21 - CHAPTER 7, GOLANOBJECTIVES Review& understand the basic neuroanatomy of the CNS, especially as it pertains to mechanism of drug action and drug access to the CNS. the basic cellular orga
SUNY Buffalo - PHARMACOLO - PMY406
SEROTONERGIC & CNS ADRENERGIC PHARMACOLOGYFeb. 12 Chap. 13 Golan (& Chap 9 for review of Adrenergics)1Regulation of Serotonin Transmission22Noradrenergic Synapse33Serotonin Synthesis Norepinephrine Synthesis44Monoamine Transporter Family55S
CUNY City - ECON - 131
AMERICAN COMPANIES: READY TO COMPETE?A survey of the big competitive issues facing American companiesWhen Peter Drucker was asked more than 25 years ago, "What will be the biggest management changes in the 1980's?" his response included this statement:
Coppin - FIN - 329
Public finance and informaiton systemsThe fiscal arm of the government warrants study and scrutiny in this volatile economy. With populist outrage growing, Americas citizens want greater insight into the internal government finances are and how they're b
Maryland - ECON - 422
Welcome to Economics 20What is Econometrics?Economics20Prof.Anderson1Why study Econometrics?Rare in economics (and many other areas without labs!) to have experimental data Need to use nonexperimental, or observational, data to make inferences Import
Maryland - ECON - 422
The Simple Regression Modely = 0 + 1x + uEconomics 20 - Prof. Anderson1Some TerminologyIn the simple linear regression model, where y = 0 + 1x + u, we typically refer to y as the Dependent Variable, or Left-Hand Side Variable, or Explained Variable
Maryland - ECON - 422
Multiple Regression Analysisy = 0 + 1x1 + 2x2 + . . . kxk + u 1. EstimationEconomics 20 - Prof. Anderson1Parallels with Simple Regression 0 is still the intercept 1 to k all called slope parameters u is still the error term (or disturbance) Still nee
Maryland - ECON - 414
Problemset1a,GameTheory(SinervoMusacchioFall2010). Questions1,2,5,9outofHarrington. Problemsupp1:Intheseaotterkidnapgame,writeouttheextensiveformgamefor themalekidnapofpup,withransomornoransompaidbythefemale,harm/release unharmedbythemale,retaliate/noreta
Maryland - ECON - 414
Problemset1b.SinervoandMusacchio,GameTheoryFall2010 Suppl.Problem1.WeworkedouttheBIsolutionofthekidnapgameforaniceGuy inlecture.WorkouttheBIsolutionofthekidnapgameforthemurderousGuy.Are theydifferent.Whyorwhynot? Suppl.Problem2.ForthetwoEFGsbeingdesignedb
Maryland - ECON - 414
ProblemSet2a Econ166a/CMPS166a Fall2010 BarrySinervoandJohnMusacchio DueOctober12,2010 1)HarringtonChapter3,#3 2)HarringtonChapter3,#5 3)HarringtonChapter3,#7 4)HarringtonChapter3,#8
Maryland - ECON - 414
ECON166AFall2010 1) Considerthefollowingextensiveformgame 1 2 2 (2,2) (2,2) (2,2) (2,2) a) Whatisthestrategyspaceforplayers1and2? b) Writethenormalformofthegame. c) Canyouarriveatauniquestrategyprofilewithbackwardsinduction?Ifso, whatisit? d) Usingthenor
Maryland - ECON - 414
Problem Set 3a Econ 166a / CMPS 166a Fall 2010 Barry Sinervo and John Musacchio Due October 26, 2010 1) Consider the 2012 presidential election game we considered in class between the (R)epublicans, (D)emocrats, and, (T)ea Part
Maryland - ECON - 414
ProblemSet3b Econ166a/CMPS166a Fall2010 BarrySinervoandJohnMusacchio DueOctober26,2010 1)HarringtonChapter6,#2 2)HarringtonChapter6#8 3)HarringtonChapter6,#12 4)
Maryland - ECON - 414
Econ166a Fall2010 1) 2) 3) 4) 5)ProblemSet4aSinervo/MusacchioHarrington7.1 Harrington7.2 Harrington7.5 Harrington7.6 Considerthefollowinggame: R P S D R 0,0 2,2 1,1 2,3 P 2,2 0,0 1,1 2,3 S 1,1 1,1 0,0 2,3 D 3,2 3,2 3,2 4,4 FindanypureNEoranysymmetricm
Maryland - ECON - 414
Econ166a Fall2010ProblemSet4bSinervo/Musacchio 1) Harrington8.7 2) Considerthewaitinggamewestudiedinclassbutconsidertwodifferentalternativesforthewaitingcost: a)thewaitingcostis9*(waittime)foreachplayer b)thewaitingcostis11*(waittime)foreachplayer Find
Maryland - ECON - 414
Econ/Cmps166A /Bio 176A UCSCFall 2008 Dan FriedmanProblem Set #1Due in class Monday, October 6. Part I. Word Problems. 1. Player #1 (the Serf) first chooses either to plant crops (P) or to hide the seed (H). If he chooses P, then at harvest time Player
Maryland - ECON - 414
Econ/CIS/Bio 166A UCSCFall 2008 Dan FriedmanProblem Set #2Due in class Friday October 17. Part I. Word Problems. 1. Find the Normal Form Game corresponding to the surprise quiz game in PS #1. Find all Nash equilibria of this NFG. Then use the original
Maryland - ECON - 414
ProblemSet1SolutionsEcon166a/CMPS166a Fall2010 BarrySinervoandJohnMusacchio 1)Harrington2.1 2)Harrington2.2 3)Harrington2.54)Harrington2.9Problemsupp1:Intheseaotterkidnapgame,writeouttheextensiveformgamefor themalekidnapofpup,withransomornoransomp
Maryland - ECON - 414
2SOLUTIONS MANUALCHAPTER 3: ELIMINATING THE IMPOSSIBLE: SOLVING A GAME WHEN RATIONALITY IS COMMON KNOWLEDGE3. For the Team-project game, suppose a jock is matched up with a sorority girl as shown in FIGURE PR3.3.FIGURE PR3.3Low Low 3,0 2,2 1,6Sorori
Maryland - ECON - 414
ECON 166A Fall 2010 1) Consider the following extensive form game 1 2 2 (2,2) (2,2) (2,2) (2,2) a) What is the strategy space for players 1 and 2? Player 1 only has one information set, therefor
Maryland - ECON - 414
Consider the 2012 presidential election game we considered in class between the (R)epublicans, (D)emocrats, and, (T)ea Partiers. Make the following added assumption to the game. Assume that each party earns an additional 0.1 payoff when they vote sincerel
Maryland - ECON - 414
Econ166a Fall2010ProblemSet4bSinervo/Musacchio 1) Harrington8.7 2) Considerthewaitinggamewestudiedinclassbutconsidertwodifferentalternativesforthewaitingcost: a)thewaitingcostis9*(waittime)foreachplayer 1 2 1 2 1 2 (30,20) (15,25) (16,6) (3,7) (2,12)
Maryland - ECON - 414
ECN 166 - Game Theory Fall, 2008 Homework Assignment 1 Solutions 1. Given the problem description we can construct the game tree as follows:2. The game tree is given below. Note the following payos structure is used: for each day that a student is wrong,
Maryland - ECON - 414
Homework #2 Solutions 1. The set of strategies for the professor is cfw_Monday, Wednesday, Friday We can see from the past HW1 solutions that there are 7 information sets for the student: one on Monday, two on Wednesday, and four on Friday. But Friday inf
Maryland - ECON - 414
Econ166a 7.7 Fall2009PracticeFinalSolutionsSinervo/Musacchio8.1 9.10 10.1 11.5 Question6 a)AsecuritystrategyforeachplayeristoplayB.PlayingBguaranteesaplayerapayoffofatleast2. b)Bestresponseanalysisshows: A B A 4,4 0,5 B 5,0 2 ,2 Forplayersitsalwa
Maryland - ECON - 414
ECON166AMIDTERM SInervoAndMusacchio FALL2010 85pointstotal 1)OnOctober14,1962,theUSconfirmedthepresenceofSovietnuclearmissilesin Cuba.ItwasthetimeoftheColdWarandtheUSandUSSRwerearchrivals.The USSRhadplacedthesenukesinCuba.ThesequenceofdecisionsfacingtheUS
Maryland - ECON - 414
Econ166aFall10 PracticeFinalQuestions QuestionsfromHarrington: 1)Harrington7.7 2)Harrington8.1 3)Harrington9.10 4)Harrington10.1 5)Harrington11.5 6)Considerthefollowing2x2game: A B A 4,4 0,5 B 5,0 2,2 Sinervo/Musacchio 7)Harrington16.2 KeyConcepts: Mixe
Maryland - ECON - 414
1A) 1B) 1C) TheonlypurestrategyNEis(Hide,Take).Wewilllearnlaterinthequarterhowto findMixedstrategyequilibria. 1D) 1E) 2) 3)Harrington2.11 Onlygame(b)satisfiesperfectrecall.Ingame(a),considerthe informationsetforplayer1thatincludestwonodes.Onenode
Maryland - ECON - 414
Econ 166ASample Midterm QuestionsSinervo & Musacchio1. Player #1 (the Serf) first chooses either to plant crops (P) or to hide the seed (H). If he chooses P, then at harvest time Player #2 (the Duke) either takes the entire crop (T) resulting in payoff
McMaster - PHYS - 1E03
PHYSICS 1E03Dr. W. Oko Office: ABB-150 e-mail: okon@physics.mcmaster.ca Office Hours: TBA Course web page (all sections) Course Outline: http:/physwww.mcmaster.ca/PHYS1E03 Course web page (this section) I will be posting news and all lecture notes here:
McMaster - MATLS - 101
Physics 1E03Test 1February 8, 2010Version 1Name_ Test Duration: 80 min Student Number:_ Instructors: G. Luke (section C01) N. McKay (sections C02 and C03) W. Okon (sections C04, C05 and C06) Mac email:_@mcmaster.ca Instructor:_Write your name and stu
McMaster - MATLS - 101
Materials Crib SheetChapter 3 Crystal StructuresAtomic Structures Atomic packing factor (APF) = Vatoms in unit cell / Vunit cell CN = number of atoms that each given atom touches in a unit cell FCC close packed BCC not close packed HCP close packed ABCA
McMaster - MATLS - 101
Page 1Materials 1M03, Test #1 2010 Version (1)Feb. 2, 2010Model Solutions MATERIALS 1M03 TERM TEST #1, 2010 Time: 90 Minutes This test contains 13 questions. You are responsible for ensuring that your copy of the paper is complete. Bring any discrepanc
McMaster - MATLS - 101
Materials 2O03/ Engineering 2O03 Term Test #1 (2003) Name: _ Student No.:_ Tutorial Section:_ Duration: 60 minutesAids Allowed: 1 page crib sheet (8.5 x 11) McMaster Standard Casio FX-991 calculator Be sure to show your work so that part marks can be awa
McMaster - MATLS - 101
= nA / VcNa density n= number of atoms A=atomic weight Vc=Volume of unit cell Na=6.023e23 Nv=N x e^(-Qv/RT) R=8.31 or K=8.62e-5 Qv=energy in J or e/v 1 cal = 4.184 Joules Computation of Wt% C1 =m1 / (m1+ m2)x100Attractive Force: Attractive energy: F= A/r
McMaster - MATLS - 101
PART I: Focus on SolidsChapters: 2,3,4,5.1The Structure of Crystalline Solids (Chapter 3)Crystals of gallium2What you should understand by the end of this chapter: The ways atoms are arranged in a solid. How crystal structure is determined experime
McMaster - MATLS - 101
Imperfections in Solids (Chapter 4) What you should understand by the end of this chapter: The various scales on which defects can form. The nature of point defects (vacancies & interstitials). What determines the equilibrium concentration of point defe
McMaster - MATLS - 101
Diffusion in Solids (Chapter 5)What you should understand by the end of this chapter: The importance of atomic diffusion for altering the structure of materials. The nature and mechanisms of diffusion. The key role of vacancies in diffusion. Ficks 1st
McMaster - MATLS - 101
PART III: Mechanical PropertiesChapters: 6,7,8.1Mechanical Properties of Metals (Chapter 6)The Manhattan Bridge, under construction in 1909, nine months before its opening on December 31, 1909.2 There are actually 3 chapters devoted to this subject.
McMaster - MATLS - 101
Deformation Mechanisms (Chapter 7)1What you should understand by the end of this chapter:What are dislocations and why are they critical for plastic deformation? The basic mechanisms of dislocation slip. The role of dislocation and other major mechanis
McMaster - MATLS - 101
Mechanical Failure of Materials (Chapter 8)The fracture of a Al bicycle crank arm.1What you should understand by the end of this chapter: The main modes of material failure. How failure is initiated by flaws. How fracture behaviour is quantified, and
McMaster - MATLS - 101
Part V: Phase Diagrams & Phase Transformations in Metal AlloysChapters 9,10,11.1Example: Building StructuresTaipei 1012Example: Aerospace IndustryF/A22 RaptorSingle-Crystal Titanium panels3Example: Aerospace IndustryPratt and Whitney F119 Engin
McMaster - MATLS - 101
Phase Transformations and Microstructure Properties (Chapters 10, 11)Martensitic microstructure in CuZnAl1What you should understand by the end of this chapter Why phase transformations are important for controlling microstructure & material propertie
McMaster - MATLS - 101
Part V: Plastics in Everyday ApplicationsChapters 14,15.Examples of PlasticsPVC: Vinyl chloride polymers. Mainly amorphous thermoplastics with very good chemical resistance Good chemical resistance, especially against oils. PS: Polystyrene. Amorphous s
McMaster - MATLS - 101
Part II: Functional Properties of MaterialsChapters 18,19.Electrical Properties of Solids (Chapter 18)2What you should understand by the end of this chapter:The physical basis for electrical conductivity in metals, semiconductors and ceramics. This i
McMaster - MATLS - 101
Thermal Properties of Materials (Chapter 19)Thermal images of a dog (left) and a snake wrapped around a human arm (right).1What you should understand by the end of this chapter: The main parameters that characterize the thermal behaviour of materials.