Course Hero

Register now to access 7 million high quality study materials (What's Course Hero?) Course Hero is the premier provider of high quality online educational resources. With millions of study documents, online tutors, digital flashcards and free courseware, Course Hero is helping students learn more efficiently and effectively. Whether you're interested in exploring new subjects or mastering key topics for your next exam, Course Hero has the tools you need to achieve your goals.

8 Pages

Lecture_7_-_basic_concepts (lacks refraction)

Course: BIOLOGY 80215, Spring 2011
School: Hebrew University of...
Rating:
 
 
 
 
 

Word Count: 304

Document Preview

to Introduction Neurobiology Lecture 7: Basic concepts in cellular Neurophysiology The electrical model of a neuron Current clamp & voltage clamp Voltage and current curves Input resistance and membrane rectifications Time constant and space constant The action potential Synaptic potential The H&H model 1 2 The electrical model of a neuron C Vm C gm I dVm dt= gm(Vm -Vrest) dVm dt = 0...

Register Now
Search

Unformatted Document Excerpt

Coursehero >> Other International >> Hebrew University of Jerusalem >> BIOLOGY 80215

Course Hero has millions of student submitted documents similar to the one
below including study guides, practice problems, reference materials, practice exams, textbook help and tutor support.

Course Hero has millions of student submitted documents similar to the one below including study guides, practice problems, reference materials, practice exams, textbook help and tutor support.
to Introduction Neurobiology Lecture 7: Basic concepts in cellular Neurophysiology The electrical model of a neuron Current clamp & voltage clamp Voltage and current curves Input resistance and membrane rectifications Time constant and space constant The action potential Synaptic potential The H&H model 1 2 The electrical model of a neuron C Vm C gm I dVm dt= gm(Vm -Vrest) dVm dt = 0 Vrest dVm dt + gm(Vm -Vrest) dVm (Vm -Vrest) I = C dt + Rm I=C I*Rm = dVm (Vm+-Vrest) dt Vm = Vrest gm = 1/Rm m = RmC 3 Input resistance and time constant I*Rm = Vm= I*Rm(1- e t/ )Vrest + Vm= V0 (e t/ )Vrest + V0= I*Rm dVm (Vm+-Vrest) dt dVm dt = 0 + Vm= I*Rm Vrest 4 Input resistance 40mV 400pA + Vm= I*Rm Vrest Vm(mV) 600 Input resistance = Rm=150M I(pA) 300 40 Vre - st 80 -120 : 5 The potential dV C = resting gNa(Vm -VNa)+gCa(Vm-VCa)+gK(Vmdt VK)+ gCl(Vm-VCl) 0 = gNa(Vm -VNa)+gCa(Vm-VCa)+gK(Vm-VK)+ gCl(Vm-VCl) C gNa gCa gK gCl VNa Vm VCa VK VCl gNaVm+gCaVm+gKVm+gClVm= gNaVNa +gCaVCa+gKVK+ gClVCl Vm= gNaVNa +gCaVCa+gKVK+ gClVCl gNa+gCa+gK+gCl 6 Input resistance and time constant Vm= gNaVNa +gCaVCa+gKVK+ gClVCl gNa+gCa+gK+gCl = g gNa+gCa+gK+gCl gNa Vm= VNa+ VCa VNa gCa VCa+ gK gCa gNa 0 gCl VCl VK gK gCl VK+ VCl Vm C gm Vre st I ons d ep end ent channels Li g and d ep en d ent c hannel s Voltage dependent channels i nd ep end ent c hannel s The types of ionic channels 7 8 The Hodgkin Huxley model of an action potential dVm C = gNa(Vm VNa) + gK(Vm-VK)+ gm(Vmdt Vrest) gNa = gNa m3h dx dt gK= gK n4 Vm C gm gNa gK Vre st VNa VK = xinf(Vm)-x
Find millions of documents on Course Hero - Study Guides, Lecture Notes, Reference Materials, Practice Exams and more. Course Hero has millions of course specific materials providing students with the best way to expand their education.

Below is a small sample set of documents:

Hebrew University of Jerusalem - BIOLOGY - 80215
Introduction to NeurobiologyLecture 8: Purkinje Cells1brain slices2brain slices3Spontaneous activity410 mV100ms5sEvoked activity5Distribution of potentials6Calcium activity7The different thresholds8Bi stability910 mV5sBi stability
Hebrew University of Jerusalem - BIOLOGY - 80215
Introduction to NeurobiologyLecture 9: LTD - Long Term Depression1LTD time course2LTD: specificityPSTH: Post Stimulus Time Histogram3LTD: Properties4Involvement of AMPA receptors in LTDinduction.Pairing PF-mediatedEPSPs with depolarizationof
Hebrew University of Jerusalem - BIOLOGY - 80215
Introduction to NeurobiologyLecture 13: models of oscillationstriggerinputOscillator 1output111Electronic model of olivary networktriggertrigger2triggertriggerOscillator 3Oscillator 4inputOscillator 1Coupling12outputOscillator 213
Hebrew University of Jerusalem - BIOLOGY - 80215
VOR gain ) output ( - . -fovea . Gain - VOR gain=E/H : -gaino .o
Hebrew University of Jerusalem - BIOLOGY - 80215
111.2.31 - Modulation of synaptic transmissionTransmitter release - Principles of neural science- KandelFrom Neuron to brain- Nicholls ? . . . . sea squirt , , - " . .
Hebrew University of Jerusalem - BIOLOGY - 80215
211.2.61 . . . . . . -transmittion line .
Hebrew University of Jerusalem - BIOLOGY - 80215
311.2.02 " - Meninges ) ( - Dura, Arachnoid- ,Pia- Dura ' . - Dura , - Arachnoid - Pia . Meningitis - - , ,
Hebrew University of Jerusalem - BIOLOGY - 80215
4 " - . . - . - . ' .
Hebrew University of Jerusalem - BIOLOGY - 80215
511.2.72 " - gain ) (. ' . . , . Vermis . '
Hebrew University of Jerusalem - BIOLOGY - 80215
6 " ' 11.3.2 . . input . - mossy fibers input . input- Mossy fibers '
Hebrew University of Jerusalem - BIOLOGY - 80215
7 " ' 11.3.6 . , - input . . ' In vitro . 002 " .
Hebrew University of Jerusalem - BIOLOGY - 80215
8 " ' 11.3.8 - output . " " . - ) (upstate ) (downstate . Inputs. - Input
Hebrew University of Jerusalem - BIOLOGY - 80215
9 " ' 11.3.31 ,LTD . - LTD - gain . ,PKC - .LTD- PKC PKC . -LTD .LTD
Hebrew University of Jerusalem - BIOLOGY - 80215
01 " ' 11.3.51 . - Inferior olive , , , Under shoot . . .
Hebrew University of Jerusalem - BIOLOGY - 80215
11 " ' 11.2.32 - - .inferior olive ) (connexin . - inferior olive - 63- connexin 34-.connexin DNA -dominant negative ' . - -inferior olive
Hebrew University of Jerusalem - BIOLOGY - 80215
21 " ' .11.3.72 . . , - - . . , -
Hebrew University of Jerusalem - BIOLOGY - 80215
31 " ' 11.3.03 - )( ) ( . )( )( . - ' .
Hebrew University of Jerusalem - BIOLOGY - 80215
41 "11.4.3 ! . , . ' . . " ,
Hebrew University of Jerusalem - BIOLOGY - 80215
51 "11.4.6 ' . " - . . - . " ) (
Hebrew University of Jerusalem - BIOLOGY - 80215
81 " 11.5.1 61 . - temporal cortex - - . trials - .
Hebrew University of Jerusalem - BIOLOGY - 80215
11.5.4 91 " . delayed match to sample 61 . - sustained . . . - . - memor
Hebrew University of Jerusalem - BIOLOGY - 80215
02 "11.5.11Brain repair . . - ' . ' ' . , " .
Hebrew University of Jerusalem - BIOLOGY - 80215
12 "11.5.51 . . ' ' . Spectrin . . axotomy .
Hebrew University of Jerusalem - BIOLOGY - 80215
22 "11.5.81 - - ' . ' . .
Hebrew University of Jerusalem - BIOLOGY - 80215
32 " 11.5.22 ) delayed match to sample 61 ( persistent acitivity . " .
Hebrew University of Jerusalem - BIOLOGY - 80215
42 "11.5.52 4 4? 4 ? - ? 1 1. 2 " 3 -4 . "
Hebrew University of Jerusalem - BIOLOGY - 80215
52 "11.5.92 - -perceptron' . - perceptron " . perceptron , -. vertical lobe
Hebrew University of Jerusalem - PSYCHOLOGY - 51202
PSYCHOLOGICAL SCIENCESpecial SectionPIAGET:A Centennial CelebrationC.J. BrainerdUniversity of ArizonaPiaget, Freud, Skinner, An odd thing about the three leadingnames of 20th-century psychology is thai, despite the deep differences that divide thei
Hebrew University of Jerusalem - PSYCHOLOGY - 51202
Health Psychology19%, Vol. 15, No. 4,303-314Copyright 19% by the American Psychological Association, Inc.0278-6133/96/J3.00REVIEW ARTICLECesarean Childbirth and Psychosocial Outcomes: A Meta-AnalysisM. Robin DiMatteoUniversity of California, Rivers
Hebrew University of Jerusalem - PSYCHOLOGY - 51202
13th International Symposium ofThe Institute for Functional MedicineBellingerChildren's Cognitive Health:The Influence of Environmental Chemical ExposuresDavid C. Bellinger, PhD, MScDavid C. Bellinger, PhD, MSC, is professor of Neurology at Harvard
Hebrew University of Jerusalem - PSYCHOLOGY - 51202
Bullies, Victims and Bystanders:A Method of In-School Interventionand Possible Parental ContributionsJudy Smith, PhDStuart W. Twemlow, MDDaniel W. Hoover, PhDABSTRACT: This study developed a method of in-school intervention that dramaticallyreduced
Hebrew University of Jerusalem - PSYCHOLOGY - 51202
Adolescent Storm and Stress, ReconsideredJeffrey Jensen ArnettUniversity of Maryland College ParkG. S. Hall's (1904) view that adolescence is a period ofheightened "storm and stress" is reconsidered in light ofcontemporary research. The author provid
Pima CC - ECON - 200
READING REPORTYour name:Jia,Linrui (Alex)Date: FEB8ST20091. Source: website http:/www.chinadaily.com.cn/english/doc/2005-02/18/content_415408.htm2. Title: LanternFestivalThe15thdayofthe1stlunarmonth3. Author:chinadaily.com.cn4. Publication date: FEB
Alvin CC - ECON - 200
READING REPORTYour name:Linrui(Alex)JiaDate: FEB15ST20091. Source: website2. Title: ThreeDaystoSee3. Author:HelenKeller4. Publication date: January,19335. Summary:HelenKellertellsherownstoryinordertoinspiremorepeopletoenjoythelifeandbestrongerinhop
Alvin CC - ECON - 200
READING REPORTYourname:Jia,Linrui (Alex)Date:FEB22ST20091. Source:USATODAYhttp:/www.usatoday.com/printedition/sports/20090202/chris02_st.art.htm2. Title: AsaddayforPhelps'fanclub3. Author:ChristineBrennan4. Publication date: FEB2ST20095. Summary:Mi
Alvin CC - ECON - 200
READING REPORTYour name:Linrui(Alex)JiaDate: Mar1ST20091. Source: website2. Title: Aresingleworkerstreateddifferently?3. Author:AnthonyBalderrama4. Publication date: February23,20095. Summary: Theessaytalksabouttheargumentsofdifferenttreatmentsbetw
Alvin CC - ECON - 200
READING REPORTYour name:Jia,Linrui (Alex)Date: 3/8/20091. Source: Arizonadailystar2. Title: Oncehestartsrunning,hejustcan'tstop3. Author:BonnieHenry4. Publication date: 2/2/20095. Summary:thisessaytalksaboutamanwhonamedbrainstarkkeepstrekinAmerica.
Alvin CC - ECON - 200
READING REPORTYour name:jia,linrui (Alex)Date: FEB1ST20091. Source: websitehttp:/english.sina.com/world/2009/0131/215057.html2. Title: 7ChinesetouristsconfirmeddeadinbuscrashnearLasVegas:official3. Author: XinhuaEnglish4. Publication date: 2 0 0 90
Alvin CC - ECON - 200
Jia,linrui (Alex)WRL 50A2/18/09Comparing Two CESL TeachersIhavestudiedatCESLforamonth,Iamverysatisfiedwiththestudyhere.TodayIwant tocomparetwoCESLteacherswhotaughtmeEnglish.TheyareLindaandChuck.LindaismySRLteacher,Chuckismygrammarteacher.ThewayLinda
Alvin CC - ECON - 200
Jia,Linrui (Alex)WRL 50A2/24/09Europeanuniversitiesdonotrequirestudentstoattendclasses.Actuallyprofessorsin Germanygenerallydonotknowthenamesofthestudentsenrolledintheircourses.Moreover,at theendoftheentirefourorfiveyearsofstudy,studentsinEuropeanuni
Alvin CC - ECON - 200
Jia,linrui (Alex)WRL 50A1/23/09A Chinese legendTherewillbeaChinesetraditionalfestivalonJAN26th,wecallitspringfestival.TheSpringFestivalisalsocalled"Nian".WhydotheChinesecallitthat?Iwillexplainitforyou.Thelegendsays,longago,therewasananimalcalledNian
Alvin CC - ECON - 200
Jia,linrui(Alex)WRL50A1/22/09About Writing IlikewritinginChinese,butIdontenjoywritinginEnglish.letmeexplain why.First,IamChinese,soIknowChineseverywell.Itiseasyformetowritea 1000wordparagraphinChinese,butIcantwritesomanywordsinEnglishatthe sametime
Alvin CC - ECON - 200
Jia,Linrui (Alex)WRL 50A2/12/09Air PollutionChinaisdevelopingrapidly,anditsenergydemandsareincreasing,aswell.Agreatdealofenergyisneededtorunthefactoriesofmodernindustrialareas.Automobile,trains,planesand bussesneedenergy,too.Asaresult,Airpollutionis
Alvin CC - ECON - 200
romMcDonald'sthowmanyareashFirstofall,ifyouwanttouselesstnaddition,ifyoukeenonthebrandastbutnotleast,productionisfennconclusion,itiswhenyouliveinA
Alvin CC - ECON - 200
Name:Linrui(Alex)JiaBookreportHeartofDarknessHeartofDarknessisachillingstoryofhorrorsetintheCongoduringthe period of rapid colonial expansion in the 19th century. It is the story Charlie Marlowtellshisfourfriends,whohaveallworkedatsea,abouthisjobsever
Alvin CC - ECON - 200
CCTV Spring Festival Gala begins at 20:00BJT2009-01-25 10:02:25 GMT2009-01-25 18:02:25 (Beijing Time) Xinhua EnglishBEIJING, Jan. 25 - The extravaganza will be broadcast live on CCTV Channel One andFour, as well as the English, Spanish and French chan
Alvin CC - ECON - 200
Alex50A3/9/2009ChineseSuperstitionsAsuperstitionissomethingthatpeoplebelievewillbringgoodorbadluckifithappens. Chinesealsohaveourownsuperstitions.MostforeignersknowChineseFengShui,whichisafamousChinesesuperstition.Forexample,thenumberofstepsinastai
Alvin CC - ECON - 200
Jia,linrui (Alex)WRL 50A2/17/09Two HostsDoyouknowthesimilaritiesbetweenradiohostsandTVhosts?Theworkofradio hostsandTVhostsissimilartoeachotherinmanyways.TheFirstsimilarityisbothradiohostsandTVhostsmustbefluentinlanguages,So thatwecanreceiveallthein
Alvin CC - ECON - 200
EricWRL 50AJan 23, 2009A Chinese LegendPeoplewillalwaysbecuriousabouttheplacesthattheyhaveneverbeentoand imaginewhattherewillbe.InChina,thereisastoryaboutChangEwholivedonthe moon.ThislegendspreadwidelyinChina,AndnearlyallChineseknowaboutthestory.Cha
Alvin CC - ECON - 200
TherewillbeaChinesetraditionalfestivalonJAN26th,wecallitspringfestival. TheSpringFestivalisalsocalled"Nian".WhytheChinesecallthat?Iwillexplainitforyou.Thelegendsays,longago,therewasananimalcalledNian.Itwasborntobeveryugly.Everyyear,theNianwouldcomedown
Alvin CC - ECON - 200
Chai 1Xinglei ChaiInstructor ZielinskiEnglish 107Section 00122 September 2008The meaning of homeThe Gentle Wholeness of Home, which is written by the American writer Elise SpruntSheffield, describes her different experiences in Africa and America
Alvin CC - ECON - 200
Jia,linrui(Alex)WRL50A2/9/09Lack of SleepThere'snoquestionthatpeopleneedtheirsleep.Ifyoulacksleep,youwillgetalotof troubles.Therearenewfindingsthatnotenoughsleepmaycausepeopletogainweight,haveno energy,andriskofcatchingacold.Anacutelackofsleepcanocc
Alvin CC - ECON - 200
Note: The following only applies to Sino-foreign marriages.Note: The following only applies to Sino-foreign marriages. Local-level marriage registrationoffices are the governmental bodies responsible for legally uniting under Chinese law man andwoman a
Alvin CC - ECON - 200
Jia,linrui(Alex)WRL50A2/23/09SADLikemanypeople,youmaydevelopcabinfeverduringthewintermonths. Oryoumayfindyoureatingmoreorsleepingmorewhenthetemperaturedropsand darknessfallearlier.Whilethosearecommonreactionstothechangingseasons,we callthosepeople
Alvin CC - ECON - 200
Jia,linrui(Alex)WRL50A2/9/09Lack of SleepThere's no question that people need their sleep. If you lack of sleep, you will get a lot of troubles.There are new findings that not enough sleep may cause people to gain weight; have no Spirit; risk ofcatc
Alvin CC - ECON - 200
Alex50A3/4/2009ViolenceinMoviesThesedaysthereisexcessiveviolenceinmovies.Ithinkthisisabigproblemfor oursocietyandshouldbecensoredforseveralreasons.First, young children who haven't learned to tell right from wrong may imitatewhat'sshowninthemoviear
Alvin CC - ECON - 200
Alex50A2/25/2009Women DriversNowadays,itseemslikemalehavebetterdriverskillthanfemale,butitwas nottrue.Infact,womendriverssaferthanman.Inaddition,moretrafficaccidents arecausedbymalebecausefemalearetoocautious.Maleandfemalehavedifferent attitudesofa
University of Ottawa - BA - 101
Summary 1.1Key word : Ctrl+home active cell returns to the first cell in the worksheet cell A1Find & Select button use to Go To cellsHold down the Alt key and press the Enter key, and then release both keys. The insertionpoint moves to a new line with
University of Ottawa - BA - 101
Summary 1.2Ctrl used to select the nonadjacent rangeInsert cell range: Cells group insert button arrow -click insert cells (verify that theshift cells down option button is selected)AutoSum feature: Sum button arrowFind and replace: editing group fin
University of Ottawa - BA - 101
Summary 2.1Change the background fill color: Font group fill color button arrow colorBack ground image: page layout page setup group click the backgroundThousands separator: Number group comma style button. Each value in the selectedrange now includes
University of Ottawa - BA - 101
Summary 2.2Built in styles : styles group click the cell styles buttonChange the workbooks theme: click the page layout the themes group click thethemes buttonFormat the titles: in the clipboard group, double- click the format painter button (Be sure