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Chapter 5 Abnormal Psychology S11 for posting

Course: PSCH 270, Spring 2012
School: Ill. Chicago
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Abnormality Abnormal Researching Psychology Robin Rosenberg and Stephen Kosslyn PowerPoint Slides prepared by: Nicholas Greco IV, M.S. College of Lake County 1 The ___________________ is the process of gathering and interpreting facts that can lead to the formulation of a new theory or the validation of an existing theory. The steps include: Identifying a question to be answered Systematically observing...

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Abnormality Abnormal Researching Psychology Robin Rosenberg and Stephen Kosslyn PowerPoint Slides prepared by: Nicholas Greco IV, M.S. College of Lake County 1 The ___________________ is the process of gathering and interpreting facts that can lead to the formulation of a new theory or the validation of an existing theory. The steps include: Identifying a question to be answered Systematically observing relevant phenomena Developing a hypothesis to explain the observations Collecting new observations to test the hypothesis Formulating a theory Testing the theory 2 Data are numerical measurements or systematic observations of phenomena. ________ is the process of repeating a study using the same data collection methods under identical or nearly identical conditions to obtain data that should have the same characteristics as the original study. A Hypothesis is a preliminary idea that is proposed to explain a set of data. A theory is a principle (or set of principles) that explains a set of data. Predictions are hypotheses that should be confirmed if a theory is correct. 3 4 Experiments are research studies in which investigators intentionally manipulate one variable at a time, and measure the consequences of such manipulation on one or more other variables. Independent variable is the variable a researcher manipulates. The cause Dependent variable is the variable that may change as a result of manipulating the independent variable. The effect ____________ variables (confounds) are factors that might inadvertently affect the variables of interest in an experiment, but are not under the experimenter's control. 5 The control group is a group of participants in an experiment for which the independent variable is not manipulated, but which is otherwise treated identically to the experimental group. The independent variable is not manipulated for the control group. Must be similar to the experimental group Bias is any inadvertent influence on factors that can affect data in systematic ways. ____________ assignment involves assigning participants to each group in a study using a procedure that relies on chance. 6 Age, education, cultural background, etc. ______________ is the distortion in data that can occur when the participants in an experiment have not been drawn randomly from the relevant population under investigation. The population is the complete set of possible participants. The sample is a small portion of a population that is examined in a study. Internal validity is a characteristic of a study that measures what it purports to measure because it has controlled for confounds. External validity is a characteristic of a study whose results generalize from the sample to the population from which it was drawn and from the conditions used in the study to similar conditions outside the study. 7 _______experimental design involves groups that already exist because random assignment is not ethical, desirable, or possible. For example, you sort groups into those who had childhood loss and experienced helplessness and those who had childhood loss but did not experience helplessness. You still try to control as many variables as you can such as age, health, education, and economic level. 8 Correlational research is used when manipulating the independent variable would be unethical. Correlation is the relationship between the measurements made of two variables in which a change in the value of one variable is associated with a change in the value of the other variable. Correlation does not imply ___________. No variables are manipulated Naturally occurring variations among measurements of different variables are compared 9 Correlation coefficient is a number that ______________ the strength of the correlation between two variables; the correlation coefficient is most typically symbolized by r. A positive relationship is indicated by any correlation coefficient between 0 and +1. Both variables increase or decrease in the same direction. A negative relationship is indicated by any correlation coefficient between 0 and 1. Variables change in opposite directions, one goes up; the other down. 10 11 12 Statistically significant refers to the condition where the probability of obtaining the value of a statistical test is greater than what would be expected by chance alone. _____________ is a type of correlational research that investigates the rate of occurrence, the possible causes and risk factors, and the course of diseases or disorders. Longitudinal studies (in studies of psychopathology) are designed to determine whether a given variable is a risk factor by using data collected from the same participants at various points in time. 13 Case studies (in studies of psychopathology) are designed to focus in detail on one individual and the factors that underlie that person's psychological disorder or disorders. Used for: Demonstrating some aspect of diagnosis, etiology, or treatment To provide support for or against a particular hypothesis or theory To train other mental health professionals Generalize from case studies only ________ ______________ 14 Singleparticipant experiments are experiments with only a single participant. These studies rely on the _____________ which is used to measure change in target behaviors as the result of some treatment. The baseline condition is A; the administration of a treatment or behavior modification is B. 15 16 ________________ is a research method that statistically combines the results of a number of studies that address the same general question. Valuable when some studies show an effect but others do not Increases the size of the overall data set May uncover a relationship that is not apparent in a single study May also be problematic File drawer problem, wherein studies never make it to publication and are not included in a metaanalysis Some studies may not have been conducted well Poor methodology 17 18 Psychologists have developed ethical guidelines for research. __________________ must be obtained from all participants. The participant signs and acknowledges that he or she understands what is involved in the study and agrees to participate, knowing he or she can withdraw any time. Participants must be debriefed after a study is over. Most studies need Institutional Review Board (IRB) approval. The safety and wellbeing of the participants in a study is most important. 19 20 Many researchers are exploring the possible role of neurological factors in causing psychological disorders. Assessment is done directly with ___________ or indirectly with neuropsychological testing or measurements of the level of stress hormones in the bloodstream. Limitations of neuroimaging include: An incomplete understanding of what different parts of the brain do Being unsure of what it means when an area is activated when a person with a disorder performs a task but not when a normal participant performs it 21 Scientists who study psychological factors examine specific mental contents, behaviors, or emotions, biases in mental processes. Assessing mental contents, behaviors, and emotions via selfreport or report by others can be inaccurate because of biases of what people perceive, remember, and report. People are more likely to recall information consistent with their current mood than information that is inconsistent with their current mood, and this is known as the _____________ memory bias. 22 Clinical interviews may be influenced by bias: Questions can be affected by an interview or by a self report questionnaire. Friends and family may be biased because they only report on the problems that they ______________________. Cultural and intellectual problems may cause a misunderstanding of the questions asked. 23 Problems with the Use of Questionnaires 24 ________________ is the tendency to respond in a particular way, regardless of what is being asked by the question. Social desirability is a bias toward answering questions in a way that respondents think makes them "look good" even if the responses are not true. Some people answer questions in a way that makes them "look bad" or worse than they really are. These people may be presenting with malingering or factitious disorder, or may be desperate to have their suffering taken seriously. 25 Acquiescence checking off agree more than disagree Can be reduced by wording half the items negatively Problems Related to "Anchoring" 26 Experimenter __________________ occurs when the experimenter's intentionally or unintentionally treating participants in ways that encourage particular types of responses. Doubleblind design is a research design in which neither the participant nor the researcher knows the group to which specific participants have been assigned or the predicted results of the study. Doubleblind studies are a way to minimize experimenter expectancy effects and other extraneous variables. 27 ___________ is a behavior change that occurs when one becomes aware of being observed. When people give permission to observe their behavior, they may subtly change what they do and say. Halo effect Social desirability 28 There are several questions researchers and clinicians want to answer when a new medication is developed or an existing one is being used in a different way. Is the new treatment more effective than no treatment? If a treatment is effective, is it because of its actual properties or because of the patient's ______________? 29 Is the treatment more effective than other treatments currently used for those symptoms or problems? What are the treatment's side effects, and are they troubling enough that patients tend to stop the treatment? How does this dropout rate compare to other treatments? 30 Placebo effect is a positive effect of a medically inert substance or procedure. Proof that the placebo effect can be quite strong in clinical research trials is that: Patients may not truly be ____ in doubleblind studies. May need to use an active placebo 31 Taking more placebo pills generally has a greater effect than no treatment Capsules do a better job than pills Injections do better than capsules Clinical staff provide too much therapeutic support More than half of those who begin a treatment in a research study do not complete the treatment. ____________ is the reduction in the number of participants during a research study. Attrition can affect the results of the study since the researcher must decide to compare either all of the subjects including the dropouts or just the completed subjects. The decision can yield either positive or negative findings. 32 33 ________________ are helpful aspects of therapy that are shared by virtually all types of psychotherapy. These include: Opportunities to express problems Some explanation and understanding of the problems An opportunity to obtain support, feedback, and advice Encouragement to take appropriate risks and achieve a sense of mastery Hope and a positive relationship 34 Specific factors are the characteristics of a particular treatment or technique that lead it to have unique benefits, above and beyond those conferred by common factors. An _____________ study is research in which treatment is provided in a way that is analogous to the way it is usually provided, but that is conducted under controlled conditions in a laboratory setting, thereby minimizing confounds. 35 Would therapy be better than no therapy? Researchers assign participants to two groups: Treatment and no treatment (waitlist control group) Researchers assess the levels of symptoms at the beginning of the study known as the ______ symptom level Researchers then assess the same variables again after the treatment period and compare the results of the two groups. A placebo control group can be substituted for a no treatment group. 36 37 The Treatment of Depression Collaborative Research Program (TDCRP) marked a turning point in psychotherapy research. The TDCRP study used a randomized clinical trial (RCT) design which had at least two groups a treatment group and a control group (usually a placebo control) to which participants are ____________ assigned. 38 CBT and imipramine were found to have been more effective than CBT alone. IPT and imipramine were more effective than CBT alone. 39 ________________ treatment ensures that all therapists who use one particular approach provide similar therapy that is distinct from other types of therapy. This is essential for RCTs which provide brief therapy over 6 to 16 sessions. The ___________ effect is a pattern in which studies conducted by investigators who prefer a particular theoretical orientation tend to obtain data that supports that particular orientation. 40 When a welldesigned and wellconducted research study shows a particular treatment or technique for a given disorder has had a beneficial effect, that treatment or technique is said to be empirically supported/empirically validated. ___________________ practice is a treatment or set of techniques that research has shown to be effective for that patient's problem. 41 Criticisms of Randomized Clinical Trials (RCTs): Exclusion criteria too narrow and not realistic Homogeneous samples which include White and middleclass Overly rigid manualbased treatment Relative effectiveness Therapy quality Common factors versus specific techniques Length of treatment Problems with DSM diagnostic groups The nature of the __________ variables Applying the results to individual patients 42 43 The ___________ relationship is the association between more treatment (a higher dose) and greater improvement (a better response). 44 45 Research suggests that the difference between a therapist and a patient, in terms of race, ethnicity, or gender does not matter. These differences do not systematically alter therapy's beneficial effect. Men and women are less likely to drop out of treatment if they have a ________ therapist. However, some patients prefer a therapist with a similar background or ethnicity to their own. 46
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Ill. Chicago - PSCH - 270
Mood Disorders and SuicideAbnormal Psychology Robin Rosenberg and Stephen KosslynPowerPoint Slides prepared by: Nicholas Greco IV, M.S. College of Lake County1In any particular year, about 8% of Americans experience a mood disorder. The DSMIVTR distin
Ill. Chicago - PSCH - 270
Abnormal Psychology Robin Rosenberg and Stephen Kosslyn PowerPoint Slides prepared by: Nicholas Greco IV, M.S. College of Lake CountyAnxiety Disorders1Anxiety is a sense of agitation or nervousness, which is often focused on an upcoming possible dange
Ill. Chicago - PSCH - 270
Dissociative and Somatoform DisordersAbnormal Psychology Robin Rosenberg and Stephen KosslynPowerPoint Slides prepared by: Nicholas Greco IV, M.S. College of Lake County1Read the textbook's discussion of Anna O. and her treatment. There's more to this
Ill. Chicago - PSCH - 270
Substance Use DisordersAbnormal Psychology Robin Rosenberg and Stephen KosslynPowerPoint Slides prepared by: Nicholas Greco IV, M.S. College of Lake County1 A _ substance is a chemical that alters mental ability, mood, or behavior. Substance use diso
Ill. Chicago - PSCH - 270
Eating DisordersAbnormal Psychology Robin Rosenberg and Stephen KosslynPowerPoint Slides prepared by: Nicholas Greco IV, M.S. College of Lake County1Anorexia nervosa is an eating disorder characterized by being at least 15% below expected body weight
Ill. Chicago - PSCH - 270
Gender and Sexual DisordersAbnormal Psychology Robin Rosenberg and Stephen KosslynPowerPoint Slides prepared by: Nicholas Greco IV, M.S. College of Lake County1Gender identity is the _ of being male or female, as these categories are defined by the pe
Ill. Chicago - PSCH - 270
Schizophrenia and Other Psychotic DisordersAbnormal Psychology Robin Rosenberg and Stephen KosslynPowerPoint Slides prepared by: Nicholas Greco IV, M.S. College of Lake County1Schizophrenia is characterized by psychotic symptoms that significantly aff
Ill. Chicago - PSCH - 270
Personality DisordersAbnormal Psychology Robin Rosenberg and Stephen KosslynPowerPoint Slides prepared by: Nicholas Greco IV, M.S. College of Lake County1Personality defines the individual's enduring ways of thinking, feeling, and behaving; and the tr
Ill. Chicago - PSCH - 270
Childhood DisordersAbnormal Psychology Robin Rosenberg and Stephen KosslynPowerPoint Slides prepared by: Nicholas Greco IV, M.S. College of Lake County1Mental Retardation is intelligence that is significantly below normal an IQ approximately equal to
Ill. Chicago - PSCH - 270
Abnormal Psychology Robin Rosenberg and Stephen Kosslyn PowerPoint Slides prepared by: Nicholas Greco IV, M.S. College of Lake CountyCognitive Disorders1Cognitive disorders are psychological disorders in which the primary symptom is _ mental abilities
University of Texas - BIO - 366
Figure 1.1A-form DNA 11 bp/turn Most RNA and RNA-DNA duplex exist in this form Shorter, wider helix than B form Deep, narrow major groove not easily accessible toproteinsWide, shallow minor groove (but lower informationcontent than major groove)F
University of Texas - BIO - 366
Box 1.2Figure 1.11Figure 1.123 copies of Pol III, 2 on thelagging strand, are thought tomake synthesis more efficientThe trombone model for DNA replication usestwo DNAPs, one for leading, the other forlagging strand synthesis. The 2 enzymes arebo
University of Texas - BIO - 366
Figure 1.21Figure 1.18Whathappenswhenreplicationforksmeet?Incircularbacterialchromosomes,asingleterminationregionslowsthetworeplicativehelicases(directionally).Thepositivesupercoilsthataregeneratedaheadofthetheforkareremovedbytopoisomerases(DNAgyrase
University of Texas - BIO - 366
Figure 2.3Figure 2.11Figure 2.6Figure 2.12Different sigma factors recognize different -35 and -10 sequences-35-10rpoD (70K)TTGACATATAATrpoE (24K)GAACtttgTCaAarpoH (32K) TNtCNCcCTTGAArpoS (38K) CTTGACAAArpoF (28K) TAAAgtttfecI (19K)CCCCATt
University of Texas - BIO - 366
Figure 2.19Figure 2.38Figure 2.20Primarily RNase III and RNase EFigure 2.24Figure 2.21Figure 2.25Figure 2.29Codons UCC/UCU both interact wellwith the same anticodon on tRNAThe first base of the anticodon can make wobble base-pairs with the third
University of Texas - BIO - 366
Figure 2.3230S subunitFigure 2.27Table 2.2EF-TsEf-Tu recyclingTable 2.1The (almost) universal genetic codeUGA also codes for selenocysteine (but thetranslational apparatus requires more thanjust the UGA triplet for incorporation)All codons used
University of Texas - BIO - 366
1. (6 points) One oriT, whose sequence is unique, is recognized by one relaxase in order to transfer the entireplasmid to another bacterium by conjugation.The other two oriT sequences have essentially the same core sequence and are recognized by a disti
University of Texas - BIO - 366
BIO 3661.Exam ISpring 2012(4 points) Guanosine 5-triphosphate 3-diphosphate2.(4 points) The C-terminal domain of the subunit is essential for high levels of transcription of theribosomal (and some other) operons. The C-terminal domain directly cont
University of Texas - BIO - 366
1.(6 points) GroE (GroEL+GroES) is a member of the Hsp60/Hsp10 family. GroEL is a dimer of aheptameric cylinder and GroES acts a heptameric cap. Fig. 2.39 describes how it works2.(6 points) ClpP (with ClpA or ClpX): cytoplasmic, non-essentialLon (La)
University of Texas - BIO - 366
1.Infect gal+ cells with +, isolate lysogen. Induce and grow to lysis. Lysate will contain a few dgalparticles due to aberrant excision that included gal as part of but lost the tail gene J. This a LTF lysateConcentrate the phages in the lysate and inf
University of Texas - BIO - 366
Figure 2.3230S subunitFigure 2.27Table 2.2EF-TsEf-Tu recyclingTable 2.1The (almost) universal genetic codeUGA also codes for selenocysteine (but thetranslational apparatus requires more thanjust the UGA triplet for incorporation)All codons used
University of Texas - BIO - 366
Box 2.5 FigureBox 2.5 TableFolding Proteins - chaperoninsFigure 2.39groE = (groEL + groES) consute one chaperone system for folding proteins correctlyA second system is (DnaK + DnaJ) - named after their genetic discovery asproteins important in corr
University of Texas - BIO - 366
Figure 2.44Figure 2.45Box 2.7BFigure 3.1Phenotype: BioGenotype: bioPhenotype: HisGenotype: hisAs we learn more, this mutant maybe called: hisG, and later: hisG4The wild-type is His+, and unless emphasis or clarity is necessary,e.g., during geneti
University of Texas - BIO - 366
The Newcombe experimentFigure 3.6Also read about the Lederberg experiment, where replica plating was inventedFigure 3.9Many common mutagens cause predominately transitionse.g., nitrosoguanidine, nitrosourea, MMS, EMS and other alkylating agents;hydr
University of Texas - BIO - 366
EXAM 1Suppression of nonsense codonsFigure 3.20Table 3.4Figure 3.21Selecting RevertantsReplica PlatingFigure 3.22Reciprocal recombination yields equal numbers of each typeFigure 3.23Complementation (no recombination allowed)Figure 3.24Failure
University of Texas - BIO - 366
Crosses involving selected and unselected markersFigure 3.26ConjugationF plasmid-containing cellF+ (male)Both cells become maleSee Figure 5.1 for more detailsNo F plasmidF- (female)F+ x F- -> 2 x F+Fx F- -> 2 x FHfr x F- -> Hfr + F- (usually)F
University of Texas - BIO - 366
2 cross-overs between a circular chromosome and alinear DNA are required to obtain a viable recombinantFigure 3.39A single cross-over between two circular DNAscan result in viability of the co-integrateInactivating genes by recombination with a plasm
University of Texas - BIO - 366
Replication mechanism of ColE1 repliconsFigure 4.8All replicons (incl. chromosomes) require at least one origin-specificpositive regulator of replication and at least one negative regulatorFigure 4.9Replication of plasmid R1Figure 4.10Replication a
University of Texas - BIO - 366
Cloning by inactivation of a selectable markerFigure 4.21Cloning into pUC by blue/white selectionFigure 4.22GTAlacZ reading frame (bottom strand; top strand sequence is shown)Initiationcodon. AGGA .-5S-D sequencePromoter-Cloniing large DNA mol
University of Texas - BIO - 366
Figure 5.6Figure 5.2F+ -> HfrFigure 5.14Occasionally, the transposable element will cause integration of the F plasmid into nonhomologous regions of another DNA molecule (e.g., the chromosome or another plasmid)Hfr -> FFigure 5.15Selecting for F pl
University of Texas - BIO - 366
Mating in the EnterococciFigure 5.18Recipient makes pheromones(small peptides released from the signalsequences of normal cellular lipoproteins)Donor contains tra functions, butonly TraC, a surface protein issynthesized at high levelsPheromone rec
University of Texas - BIO - 366
Figure 7.1Figure 7.8A collection of PodoviridaeCapsidgp10A+BInternal coregp14, gp15, gp16Headproteingp6.7Connectorgp8Tail proteingp7.3Major tailgp11, gp12Tail fibergp17capsidtailfiberfiberLife cycle of phage T4Figure 7.2
University of Texas - BIO - 366
Exam 2Average=57.6Median=59Exam 1+2Median=120.5Life cycle of phage T4Figure 7.2Figure 7.8http:/bilbo.bio.purdue.edu/~viruswww/Rossmann_home/movies/movies.phphttp:/www.mansfield.ohio-state.edu/~sabedon/bgnws020.htm#submissionsFigure 7.3All trans
University of Texas - BIO - 366
Degradation of a bacterial capsule by phageT7 Phage displayBox 7.2Figure 7.8Figure 7.14Fusions to the non-essential Hocand Soc (both referred to as headdecoration proteins are used forT4 display phagesFusions to the coat protein(gpVIII) or the a
University of Texas - BIO - 366
The phage developmental cycle is synchronousFigure 7.2A600TimeS107S105Figure 7.20Control of lysisRecombination with phage: infect a permissive cell with a high multiplicity of two parentsFigure 7.21Complementation: infect a non-permissive cell w
University of Texas - BIO - 366
Figure 8.7Plaques of phage are turbid, especially in their centerThe light source is underneath darker spots mean more light is coming throughThe two life-cyclesFigure 8.1The linear genetic map of Figure 8.2PAQThe circular genetic map of Figure 8
University of Texas - BIO - 366
Figure 8.4cII O PcII O PFigure 8.5gpN binds to boxBE. coliTGCTCTTTAACAABound gpN recruits the Nus proteins, which can then bind to the mutantboxA, interacting with RNAP to directtranscription antiterminationAntitermination by gpN allows maximal t
University of Texas - BIO - 366
Figure 8.13Figure 8.14Induction of to form a transducing lysateThis is specialized transduction can only acquire bio or galPart of the + genome must be lost in the transducing particle:pbio phages are viable and make plaques they only lost non-essent
University of Texas - BIO - 366
Figure 8.18Figure 8.19Figure 9.1Figure 9.2Figure 9.3Figure 9.4Figure 9.5Figure 9.6Figure 9.7Figure 9.8
University of Texas - BIO - 366
Figure 9.8Transposition is usually a rare event the Tn 3 resolvase represses transcription of tnpA, the transposaseFigure 9.9DonorNon-mobilizable plasmidRecipientFigure 9.10Non-mobilizable plasmidConjugative plasmid (not chromosome)Figure 9.11Re
University of Texas - BIO - 366
Transposon mutagenesisFigure 9.21Figure 9.26Using phage Mu, as a transposon (Mud(lac), to make gene fusionsMu ends (inverted repeats)Figure 9.27A deletion variant of Mu: mini-Mu, can be used for in vivo cloning and transductionFigure 9.28Infection
University of Texas - BIO - 366
Exam 3Average=51.4Median=54.5Exam 1+2+3 Homologous RecombinationE. coli:Eukaryotic homologous recombination:Several factors required in E. coli havehomologs in humans and othereukaryotes:E. coli recombinase RecA = Rad51 ineukaryotes (plus Rad51
University of Texas - BIO - 366
RecombineeringBox 10.3ssDNA does notrequire exo or gamExo degrades from the 5->3direction, producing a 3-ssDNAtail on the PCR product then binds the ssDNA tailand catalyzes strandinvasion just like RecAFigure 11.1Figure 11.2Figure 11.38-oxoG
University of Texas - BIO - 366
Figure 11.14Removal of bulky lesions in DNA by UvrABCRecombinational repair after the replisome encountersa lesion on the leading strand template strandFigure 11.15Another model invokes fork regression to repair leading strand template damageFigure
University of Texas - BIO - 366
Figure 11.20Figure 11.21Error-prone DNA polymerases (DNAP IV and V)[also DNAP II]Table 11.2Table 11.3HTH (helix-turn-helix is a common sequence-specific DNA-binding motifBox 12.1Complementation in the lac operonFigure 12.1Figure 12.2Figure 12.3
University of Texas - BIO - 366
There are 3 operator-like sequences in the lac operonFigure 12.5The importance of the pseudo-operatorsFigure 12.6lacUV5 AMoving the lac operon close to tonB (T1rec)Construct lac [F (Ts replicon) lac+]Select Lac+ at high temperature frequency ~10-4
University of Texas - BIO - 366
Figure 12.18AraC can only activate transcription in the presence of arabinoseFigure 12.19Figure 12.20Figure 12.1590% of the regulation of the trp operon is by the TrpR repressorFigure 12.17A subtle change in TrpR structure in thepresence of Trp al
University of Texas - BIO - 366
Exam 4Average = 63Median = 66Exam 1 - 4Table 13.1Figure 13.1Box 13.1B. subtilis regulator CcpA (Catabolite control protein A)Is the counterpart of CAP-cAMP regulationFigure 13.2Different modes of activation by CAP-cAMPFigure 13.3lac one of the
University of Texas - BIO - 366
All DNA synthesis goes in the 5-> 3 directionpppN53OHNpppChain growth in 3-> 5direction?No 3-deoxynucleoside triphosphates ever found!3pppN5Deoxynucleoside 3-triphosphates5OH53Chain growth in 5-> 3direction533Deoxynucleoside 5-triphosp
University of Texas - BIO 347 - 347
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University of Texas - BIO 347 - 347
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University of Texas - BIO 347 - 347
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University of Texas - BIO 347 - 347
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University of Texas - BIO 347 - 347
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University of Texas - BIO 347 - 347
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University of Texas - BIO - 320
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University of Texas - BIO - 320
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University of Texas - BIO - 320
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University of Texas - BIO - 320
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