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Course Number: MATH na, Winter 2013

College/University: Cleveland State

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R{|S:F273~lQ_ UDCUSMONx:10142 ^=Y }'Y \ UxXf[MOe ev:+}IgcSyvSL'`xvz 2004168fN f[yTy: H_Cg yv{t f[\O 28t^1g4el3]N'Yf[UxXf[MOe ev:+}IgcSyvSL'`xvz \O:!SO8NR\Sq!J12),l8\! c[Ye^: OSRc[Ye^: u~oRYec TekN~ Nz\^ USMO:l3 NNNf[ USMO:l3)Y.ULuSgPlQS USMO: ecNeg:2007t^1g4LI f[MOcNUSMO:l3]N'Yf[TAXOLEXTRACTIONPROJECTFEASIBILITY DEMONSTRATIONSTUDY Author:Chenq\iquan SuPervisor:AssociateProfessorZhaoHong...

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}'Y \ UxXf[MOe ev:+}IgcSyvSL'`xvz 2004168fN f[yTy: H_Cg yv{t f[\O 28t^1g4el3]N'Yf[UxXf[MOe ev:+}IgcSyvSL'`xvz \O:!SO8NR\Sq!J12),l8\! c[Ye^: OSRc[Ye^: u~oRYec TekN~ Nz\^ USMO:l3 NNNf[ USMO:l3)Y.ULuSgPl R{|S:F273~lQ_ UDCUSMONx:10142 ^=YQS USMO: ecNeg:2007t^1g4LI f[MOcNUSMO:l3]N'Yf[TAXOLEXTRACTIONPROJECTFEASIBILITY DEMONSTRATIONSTUDY Author:Chenq\iquan SuPervisor:AssociateProfessorZhaoHong ShenyangUniversityofTechnology Shenyang,P.R.China January4,2008rR'`f ,gNXf:@bHTNve/fb*NN(W[^c[NLvxvz] \OSS_vxvzbg"=\b@bw,dre-Nyr+RRNhlT"v0We Y,e-NNS+TvQNN]~ShbdQvxvzbg,_NNS+T:N_ l3]N'Yf[bvQNYe:ggvf[MObfN@bO(uvPge"NbNT ]\OvT_[,gxvz@bZPvNUO!.sGW](We-NZPNfnxvfv^h :yN"a" ~{T:P[_seg:l-N.-!+N sQNeO(ucCgvf ,gN[hQNl3]N'Yf[gsQOYu!O(uf[MOev[,sS: f[!hgCgOYuNevYpSN,AQegTP;f[!hSNlQ ^evhQbRQ[,SN]q_pS!)pSbvQNY6RKbkOX[ e" (O[ve(W[T^u_dk[) ~{T:[^~{T:NT,eg:N0Y/,.XdNw_N 4OVE~NmNSOSvSU\,bVvyv^v{t!j__NnNVEch,(W NN'Yv]z^-N_eQNyv{tvi_,yvvSL'`\O:Nyv{tv NR,wQgMRw'`T~y{hQ@\vyr'`,ZP}YSL'`/fyvb%vMRcTOnc" +}Ig/fNLu NetQvbLvuircSoir,[uS]LvTly'`sNzLvwQg_}Yv uHe"N~FIgSe-NcS+}Ig/fSoirv;N_,V+}IgcSwQg_ v>yOHevT~NmHev,@bN+}IgcSyv(WVQYvxvz(WNt^_0R_vS U\" ,geN+}IgcSvyvofN~eQKb,cgqvyvSL'`bJTBl,N yvv@bSevDn`Q,yv@bYsXSb/g!D!^:WI{eb[yvL NSL'`v" ,ge\N\O[EdQv+}IgcSyvSL'`bJT:NW@x,(uyv{tw ,~TyvSL'`xvzvelT },;`~QyvSL'`elYUONwQSO yvv~T,YUO(W[Evyv-N_N(u"v^Ntebib;`~NYUOOyv SL'`0OvgHe!wQ[Evd\O'`,:NvMRNTvlQSLNTyvvSL'`0O T^(ucONSN9ev_" sQ.:+}IgcS,SL'`xvz,yv{t _TaxolExtractionProjectFeasibility DemonstrationStuR Abstract WiththedeveloPmentofinternationaleeonomieintegration,China,5eonstruetion Projeetsinthemanagementmodel15graduallymergewiththeworld,inanumberofmajor construetionProjeetsintheintroduetionoftheeoneePtofProjeetmanagement,andProjeet feasibilitystudyasaPartofProjectmanagement,forwardNlookingandeoNordinatethe overalleharacteristicsoftheProjeettofeasibilitystudy15thePrerequisiteandbasisfor SUCCCSS. Taxol15theworld,5emergingbioNextraetantieaneerdrugsonovarianeaneerandbreast eaneerhasgoodeffieacy.Rawmaterialsextraetedfromtheyewaeeesstothedrug15the Primarymeansforextractionoftaxolwithhighsoeialandeeonomiebenefits,extracttaxol researehProjeetsathomeandabroadinreeentyearsbyfasterdeveloPment. ThisPaPerstartfromonthebaekgroundoftaxolextraetProjeet,Feasibilityofthe ProjeetinaecordaneewiththenormsofrePortingrequirements,Fromtherawmaterialsfor theProjeetresources,Projeet.5theenvironmentandteehnology,eapital,market,andother asPeetsoftheProjeetcarriedoutafeasibilitydemonstration. ThisPaperwillbewrittenbytheactualauthorofTaxolextraetionProjectfeasibility reportforthefoundation,usingprojeetmanagementwowledge,theProjeetfeasibility studywiththestudymethodsandelements,summeduPhowtheProjectfeasibilitystudy methodseombinedwiththesPeeifieProjects,howactualProjeetstouse.Itsummaryhow toensurethattheProjectfeasibilityassessmentforaneffeetive,Praetiealworkabilityfrom thetheoretiealasPects.ltProvideanimPortantreferenceandimProvingthewaytothe PresentdifferenteomPaniestoassessthefeasibilityofdifferentProjeetsandaPPlications. 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'k2mvSV["ncgsQDeN~,VYsY'`Lvu`Npekt^~:N399.44NN, 0O[+}IgBRgBlvNpe`S20%(sS79.85NN)ckN(u20/e,(u 1597.77N/e/kt^,(u+}Ig479.33lQe,R N[xvzT4N^,0OVYv t^(u:N600lQe"vMR+}IgBRO(unfMv/f(WS!'k2mTe,gI{S V[,[Evt^m9:N300N400lQe" (WVxQWvO(u+}IgluNuz9NN0RNN$NCSCQ"e5[lQS (W1999t^hQt+}Igv.U7NCQ,`Se5[lQShQt^.Uv7.3%"h 3.1/f+}Ig(WhQt^:Wv.U`Q",{NzYUOgHe[eyvSL'`0O h3.1+}Ig.UrQ Table3.1Taxo!salessituatlon t^N 1999 2000 2001 .U(NCQ)Xs(%) 8.13 9.41 40.17 15.74 27.52 2002 2003 ~15 ~20 25 33.3 SNwQ+}Igv.U(WNkt^20%v^XR,Nebh:yNNNv~Nm bSR(WX:_,Te`[oirvS^_N(WXR" ncVY;SoN[0O,+}IgSeovuNb,gY(WklQe25NCQ]S, FOe5[\vQR]b6RBR(Yl\BRbm)TzsSGS<P:NklQe500NCQ,)R m20PKNY"e*`NNOY6RoS[[uN+}Ig6RBRKN\"}e|nx~pe W[,gsQeb0OhQt+}IgSeoN'Y(Wkt^350lQe]S(9hnc6RBR.U` Qc{QegvpeW[)"@wfYvS[ReQ0R+}Ig6RBRuNLR,SNeNT6R BRN[+}IgSeovBl\F~ NGS" +}Igs]b:NNLu,{Nvb$voir"@w+}Ige(uvNeSs,(W 21N~+}IgMRofeP^" 3.2.2VQ^:WRg @wQt^+}IgNNvNeSU\,+}IgONvNeXR,SU\RgNRP6R vxO~FIgh@b&^egvevf>f"N`)Y6qNv~FIgNneg'YvS evBl,uv~FIg,$\vQ/fNWSN&^v~FIg,1uNvQhv-N+}Igv+T, @bm0RvxO_Nf:N%N,]~YNo4Nmp~v0Wek"QN[uszRiirvOb, V[T0WeR'YN[dk{|iryvOb,ybkqNxqNO,Vdk,VQv+}IgS[k eW,g NYNSeO^N NvrQ,dNBhgVffO`SvSeuN,NWSIl_! 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NwmTwmWSTlQS[RS]NP,SU\ 6kNN"(Wdkb_RN,ONSOXbDnv0N['`TRycSb/gvHQ'`,(W^:W zN-NO_}Yv^:WN" 3.2.5+}IgN<hRg (l)NMOvq_T"+}Igeu/fS_MR NXNvbLvoir"o N^Neg,N <hE\NN,V6qg+TNO_TDngPI{[SV,FON<hvMO,vnxgx^:W vbU\"VBMSlQS33mYu/eBRN:N175CQ//e,eQbV^:W~:N200CQ //eN N,VN+}Ig30mg//e,.UN1200CQ//e,NkMO`\(u20/e,9(u (W4N6NCQ,`T;SbgmtQS"+}IgBR(WVQ^:W600CQ]S//evN MO N,^:W[1\Sk'Y,7hvNMO(WVE^:W N_NMb.gzNRv" (2)VYN<h"+}Ig/fNASt^-NSsvgvbLvoir,VFDA]yb Q(uNuS]LvTsNzLvvlu"V(WbV4N^(uNTe,kKQ9(uS9NCQ" ncb[,1997t^V^:WBl~IOokg,.U5NCQ,1uN+}IgOovb Lvyr'`,N<h,VE8^.UNkKQ:N700N1100CQ" (3)VQN<h"VQS[N,;NNSeo:N;N,BRvN_\" VQN<hh3.2"l3I_N'Yf[UxASf[MOe h3.2+}IgVQN<h`Q Table3.2TaxolPrieesituationinChina ^SuNS[N(lQe)<h.UN(NCQ) +T)70%110N130 NWSIl_uirb/ggPlQS nq0CUOL]kJS]nUN]ddNbenUCOnlkQbUnjSQQnJYN111,CC1,1.+T99.5% 0%0%0%0%0%QNSJkQUnUCUQNQQJSRn-QQOJJSQOJJ 2 NwmYq+}Igeb/ggPlQS 20 2 3 5 5 Ym_lNl;SoSlNgPlQS lNS'Y6quir6RogPlQS U[_ylQS [eY[euir\SzgPlQS *m_leGSuirS!:S pS~S6RogPlQS NS-Nt7Nf[yxY \N7Y+}Ig p0qnU0012.1Jl... l0 36 'YN99.3% )99% 99.3~99.6% nCU`UlJpf)01.]QYN]N)99% 99.50% |T 3.2.6N<hpTRg (l)Blq_T"sNzLvTuS]Lv/fNLu NSusgvV*N$vuuKNN"sN zLv/fYsY-N8^v$v,`SsY'`$vv29%,(WVk10*NYsY-N\gNNSu sNz$v,YsY-N{kNsNzLvvNpeN!kNLv"1uNnTsXV }vsQ|,uS]Lv (W~NmS0W:SHT NGSKNR"lLvSeN+}IgY~ON^Bl,*gegQt^yBl_ \bR+}IgN<hv Nlb" (2)Seq_T"+}Ig(W~FIg(hv)-Nv+T:N0.02%]S,gS-Nv+T R:N0.005%]S,RKN~FIgu:Nba,R^VgP,EeiirDnb:N+} IgNNSU\v6R~V }"'k2m~FIgDnQ~,)Y6qDn?SON,RKNTV [DnvOb,Nek6R~+}IgSevegn,_N\ bSeN<hveGS",{NzYUOgHe[eyeSL'`0O (3)zNq_T"1uNNTvzN'`evR:_,+}IgN<hOgNnvR,FO NO'YN NGSR"9hnc^:WRg,VQY+}IgNTN<hN$Nt^NOg*Y'YvR a"+}IgNTuNSN[,vQNTzNpN(WNN<h N,(WNNTb/g+T N" VdkNOQs+}IgN<hb" NN Nv+}Igyv^:WRgSNwQ,yvvNTDR<Pg,VEVQv N<h3z[,^:WBl(WNevX,zN[KbN/f_Y,yvwQg}Yv^:WMR of"FOTe_Nla0R,yvveQXW,`eQVE^:WS_VFDA v,/fgvS_v^"FONT(WlgS_FDAe,SN(WVQ.U, VQvBlO6q_'Y,@bN/fwQYyv Nl@bv^:WagNv" 3.3yvb/gS[eeHhRg /b/g/fN*Nyvb%vsQ.,yvSL'`0O-N[b/gW@xvNeQ,g yv@b(uvb/g(WVQYvHQ'`!bq^,SQb/gv~Nm'`l.0]"0yvS L'`0O~TTy },cQgsOvbeHh" +}IgvcS]zN,Sb|x!YNxmS!/lNRM!ExgB\g!;m'`x1 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RycSz-Neg"dNHPLC(vQ-NSbckvNHPLC!SvNHPLC)Y,gB\ r1(TLC)l!_g5uRr1(MEKC)TAmr1(HSCNCC)I{" Ty{|WvHPLCTTLCvqQT:p/f:}\,NNe8^'Y7hTgY t,N0RJS6RY!jv4ls^" (4)4NLuAmSOSl"4NLuSb/g(SFE)/fNS]Ry-NQsve b/g"SFE\ O~vTg:gnBRS]z~T:NNSO,/)R(u4NLuCOZOo vn'`TnR,NS{|<OlSOvibce|pe,\WSONSirgHe0WRy!cST ~S[.3N.7]",, \4NLuAmSOS(SFE)b/g_eQ0R+}Igv~Sz-N,Q\N+T/lg:gn BRvO(u,/fNyNalgsXveb/g"SFEg8^(uvnBR/fCOZ,[,gek,(W cSNir-NSekYu,VN(uo[hQ^eg,yb/gwQgvQryrvOp" 1992t^,JenningsI{N(ueoZTReQYN9e'`BRveoZ\OsrEnBR,(W3lsK v)n^T18.07N25.79MPavSR\SL+}IgvcSxvz,~gSshv-Nv+}Ig 'YR_0RgHevcS,cSs0.08%(8^elN:N0.01%),N[ +}Igvb'`k O~vUS~YNcSHeg}Y"NairI{N(u+T0.001%N]%vNn bYN[wvCOZ\OnBR,(W43.4MPa-308KNN(u4NLub/gcS+}Ig_N_Nnav Heg"CasterI{NN~FIggSTZZPSe,(u4NLub/gcS+}Ige,HQN~,{NzYUOgHe[eyvSL'`0O COZZPnBR,NdSSe-Nv{|,6qTReQYNNnBRvg'`,O+}Igv Ns0RN0.04%" vQNelgY:/XllI.8]!0/RylI.9].,I{" NQyel-N,mvS1uN'YO(ug:gnBR,[sXvq_T]'Y,N^\N |c6k,NTv6esNO,@bN,geHhNNQ:VvSvMRc/fNTSe_{ :Nxm,NNT!jSuNSP"r1l^\N|6Rv6k,S_0R~^vNT, FOVuNe,NT6esNO,NTMRgv'Y!juN"XllTRyl ^\NY(Wxvz6kvb/g,vMRb/gbq^N,NT'Y!jv]NSuN"N N QyelX[(Wg:gnBRvkYu"4NLuAmSOS(SFE)l}6q_NX[(WMRg YI{bD'Y,NhVYBl,[NXTvb/gBl_Nv:p,FOVvQ/wQg eg:gnBRkYu!NTvcs!esXalg!b/g^\NS_NvMRl4ls^I{N|R Op120N22],0@bN~TkNTeHhT,Q[(u4NLuSb/g(sFE)eg\O:N,gy v@b(uvb/gel" (u4NLuCOZS]z,gHe0WO+}Igv6esS;m'`+T,NY b'`'Y,RSc6Rz^,gHeONT(,(u4NLuSlNvQN] zvkvQO'`YN: enBRkYu,NT~)Y6q" e/N^0,uN[sXealg,^\~r]S" d\O)n^NO,c8^)n,Nq_Tuir;m'`bN,NTNf'lS!R" 4NLuCOZSlwQgo}Yvb'`,n^S9hnc]z,ew!6es !NT(}Y" d\Ob,gNO,NvQNelvkSf[nBRO(u\,SMNOb,g" fd\O,SRyNSO,]zAmz{US,S[scSc6R,ONT(" 3.3.2yvb/geHhRg (l)SL'`xvz6kvyv]zb/geHhSRN,g: l)HQ'`SR"(uvb/g(WNT4ls^!]z4ls^TY4ls^NebwQgHQ '`:l3l:NNf[UxASf[MOe 2)^'`SR"(uvb/gQ&{T^S0W:SvDnagN,TS_0WvNMb }(;b/gB\!kTS_0W~Nmb/gSU\v[E4ls^; 3)[hQS`'`SR"(uvb/g^/fbq!S`![hQv,[d\ONXTTsX lgqS[bN)Rq_T; 4)l^'`SR"(uvb/g^NSS_0W?e^l_[TSU\RSgsQ ?eV{" (2)yv]zAmz"+}Ig4NLuSvte*N]zAmzV3,l" ~~FIghv!gSI{I{I{|xxxxmlllV6exm +}+}Igr^qq V3.1+}Ig4NLuSll_zAmzV F19.3.1SuPercritiealextractionProeessdiagramofYTaxolExtraetion (3)SPgeSm[Rg"SPgeSm[Rgh3.3" h3.3SPgeSm[ Qble3.3RawmaterialsandconsumPtionoffixed ^STyUSMO<hm[ l~FIghv(T 2YN(T 2000102 (T(TN'lSx mRBR (T KWh380V30000 4l5u }lnL`g0.3MPa6000 (4)Y]zAmzSY~b"(Wte*Nyv]z-N,4NLuS/f8h_vb/g, 4NLuAmSOSRyzvSt/f)R(u4NLuAmSOvnRNvQ[^vsQ|,sS)R (uSRT)n^[4NLuAmSOnRvq_TLv"(W4NLur`N,\4NLuAm,{NzYUOgHe[eyeSL'`0O SON_Ryvir(c,OvQgb'`0Wbg'`'Y\!lpNOTRP['Y\vbR O!kSQeg"S_6q,[^TSRV@b_0RvSirNS/fUSNv,FOSNc6R agN_0RgsOkOvmTbR,6qTPRQS!GS)nvelO4NLuAmSOSbnfl SO,Sir(R[hQbW,ggQ,N0RRyc~vvv,@bN4NLuSz /f1uSTRy~Tbv" SYv]zAmzTY~bV3.2" V3.24NLuS]zAmzTY~bV F19.3.2SuPereriticalfluideXtractionProeessandequiPmentdiagram 4NLuSnNR N'YSOSR:NkQR:SBRO^|~,NO)n|~!S |~!S|~!Ry|~!9e'`BRO^|~!_s|~T{:gc6R|~"wQSOS bN'lSxleQl!ShV!RyhV!S):g!N'lSx!Q4l:gI{Y"1uNS z(WSNL,@bN[YNSte*N{|~vS'`Bl,uNz[ s_:gRvc,SN'Y'Yc|~v[hQS`'`,v^MNOLb,g" (5)yv;NY`Q"yv;NY`Qh3.4"l3]N'Yf[UxASf[MOe ^S h3.4yvWY`Qh Table3.4MajorequiPmentrableoftheProjeet Ty<hWSpeYl SS |x:g 4NLuS pr^Y y_:g nn PP QP hNhV S:g 100NA WYWYWYS WYS 3.3.3yv[eeHhRg 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(3)SL'`sQlW@xpencv("W@xpencv}YOWq_Tyv/f&TSL, /fyvSL'`bJT-NsQ."dQbJT__O:NNObJT_,(uoNvpe nc,O%Nq_Tv~g"@bN(WSL'`bJTdQ-NS3zePve_,S[ bv[O[vDe,NOyvig\S" (4)SL'`zgia"SL'`bJT-NggvsQNN }(NXT @bZPviebvRg,NNTv^~yvN*Nv[v[hQagN"FOS/fyv 1\Ogi,bNZPv/f\ic6R0RTtv!SbSvV" NQ[,[NvQNlQSLyvSL'`0OwQgvPtaIN,S:NvQNlQ ScOgRvSOnc"FONTvyv^~Tv`Q!~~of!bDgNS N33-l3l_N'Yf[UxASf[MOe iOP}YegLv^vyvSL'`xvz,v^N(W(uz-NNeRNOckT[ U,yvSL'`0O]\OwckY:NlQSbD{tR N<P!Se.s [l]DennisLoek.yv{t[M].'Y%m:WS_'Yf[QHr>y,2005. [2]_V.{feoyroKbQ.SN:NlkSuQHr>y,2007. [3]HolmesFA,FryeD,ValeroV,etal.Phase1studyoftaxelanddoxorubieinwithGNCSFin PatientswithoutPriorehemotheraPyformetastatiebreastcaneer!Jl#ProeASCO,1992. [41Rm,sSf,sSf.~FIgDnN+}IguNiQ.SN:iirDnN,!sX,1994. l5]szV;N.ye0OtN[R.SN:~Nm8f'Yf[QHr>y,2006. =6][8A.KQ#_f.sXNDnN<P0O.SN:-NVNl'Yf[QHr>y,2002. 07]p,RNS;N.-NowNCgObT-Nbb/gcWS.SN:-NV;SoybQHr>y, 2005. [88TTVf.^:WRgNKm.SN:-NV~QHr>y,1992. =9]4bhTN!NziRgb/g.SN:Sf[N1NNQHr>y,2007. 110]v.bDyv0O.SN:nNS'Yf[QHr>y,2007. [llJ-NV;Sf[yf[boirxvz@biS[.'YT[h8TD(W-NIoSf[cSRyv^(u.SN:-N IoBg_,1980. [12]_`_;N.)Y6qNircSNlNzf[.SN:-NV{]NQHr>y,2006. =13]DattaNN,BaruahAP,PhukanP.SuPereritiealExtraetioninthePharmaeeutieal Industry.Chem.Eng-world.1991# [14]ZoselKetal.Angew.ChemNIntEd.Engl.1978 =15]StahlE,QuirinKW,GerardD.DenseGasesforExtractionandRefinjing.berlin,Heidelberg,New York:1986 =161LackE,MarrR.SeP.Sei.andTech.1998. =171ReverchonEJ.SuPercrit.Fluids.1997. =181uuQ,O_%f,ss%fI{.Xl(WiircS-Nv^(u.SN:-NIoBg_,1999. =19]Qt^s^.Ryb/g(W-Noxvz-Nv^(u.SN:-NboBg_,19%. =20] _\o,fQRR.,{NJ\hQV4NLuAmSOb/gS^(uxOle.\.N]:!998. 7218Hy, _b~.Sf[U\.SN:1999. 122]1g:_.4NLuAmSOb/gNStT^(u.SN:Sf[!_NQHr>y,2000. =238RN^.ON{tT.SN:-NV"?e~NmQHr>y,2005. =248r^Vs.bDyv0Of[.NS"~'Yf[QHr>y,1998. N35-l3!_N'Yf[UxASf[MOe [25]DavidYardley.SuccessfulITProjectDelivery:LearningtheLessonsofProjectFailure [M].2002. [26]YO^f.5}Nzyei{t6.'Y%m:'Y%mNf[QHr>y,2006 [271-NVVE!NzTlQSW.-NVbDyv>yONNSi:N:gG.SN:-NV"~Q Hr>y,2007. =28][~sO,r^zV,s~\W.SL'`xvzNyv0O(,{bkHr).'Y:NS"~'Yf[Q Hr>y,2007. 729] __:_,_V.+}Ig(W'lSB\gz-Nv3z['`xvz.SN:)Y6qNirxvzN_S, 2000. =300 __:_.ckvTSvgB\g~TRy~S+}Ig.SN:uir]zf[b,2000. Sl]Y[{Qf[.bDyv0Of[.[:[0WVQHr>y,2003. 1321R`f[.eNT{tf[.b:V]NlQHr>y,1988. [33]J.RodneyTurner.HandbookofProjectNbasedManagement.2005 [34]b[.yvN0O(21N~yv{t|RRYePg).SN::gh]NQHr>y,2005. [35]"?elQO^YXTORlQ[."Rb,g{t.SN.~Nmyf[QHr>y,2003. [36]Ye'Yf["Rf[|.ON"R{t.SN::gh]NQHr>y,2005. [370_^,NgvV.^yvbhbNQV{NiRg.SN:4l)R4l5uQHr>y,2007. 038]~/cNS."R{t.SN::ghlNNQHr>y,2005. [39]AlanWebber.TheBestOrganization15NoOrganization[M].USA.Today,1997. =4001g`I{."R{tNRg.mg]:Ym_l'Yf[,2000. [41]Struekenbruek,LC.Thematrixorganization=J][M].ProjeetManagementQuarterly,1979. [42]V[RYXTO.sQN^yvLSL'`xvzvL{tRl.SN:1983." w_a"[^u~oRYec[bvsQ_Tc["u^f[^ZS!lf[%N(!wQg 0N[vON[~"Nu^ N,bNNf[0R`NNNNw,N_N_N_Y ON{tebv~,Sv*SEm,(Wdkyrha"!
MOST POPULAR MATERIALS FROM MATH na
MOST POPULAR MATERIALS FROM MATH
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