Register now to access 7 million high quality study materials (What's Course Hero?) Course Hero is the premier provider of high quality online educational resources. With millions of study documents, online tutors, digital flashcards and free courseware, Course Hero is helping students learn more efficiently and effectively. Whether you're interested in exploring new subjects or mastering key topics for your next exam, Course Hero has the tools you need to achieve your goals.
13 Pages
HM161
Course: HUM 161, Spring 2008School: Vanderbilt
Rating:
Word Count: 349
Document Preview
Laboratory Experimental Research HM161 Genetics & Politics 1.29.08 Scientific Method Observe Hypothesize Experiment Analyze Laboratory science is very controlled. devcell.bio.uci.edu/LABS/Labsv2.htm Candidate Approach: Reverse Genetics Genetic analysis in which gene function is altered and the resultant phenotype/behavior is analyzed Techniques Used: 1. Genetic Mutations 2. Gene Silencing 3....
Unformatted Document Excerpt
Coursehero >> Tennessee >> Vanderbilt >> HUM 161Course Hero has millions of student submitted documents similar to the one
below including study guides, practice problems, reference materials, practice exams, textbook help and tutor support.
Course Hero has millions of student submitted documents similar to the one
below including study guides, practice problems, reference materials, practice exams, textbook help and tutor support.
Laboratory Experimental Research
HM161 Genetics & Politics 1.29.08
Scientific Method
Observe Hypothesize Experiment Analyze
Laboratory science is very controlled.
devcell.bio.uci.edu/LABS/Labsv2.htm
Candidate Approach: Reverse Genetics
Genetic analysis in which gene function is altered and the resultant phenotype/behavior is analyzed Techniques Used: 1. Genetic Mutations
2. Gene Silencing 3. Transgenesis
How is this approach used in the lab?
http://learn.genetics.utah.edu www.biology.uc.edu/faculty/Buchholz/ http://publications.nigms.nih.gov/thenewgenetics/images/ch
A glial amino-acid transporter controls synapse strength and courtship in Drosophila
Grosjean et al. Nature Neuroscience (2007)
A single gene controls courtship behavior in male fruit flies
genderblind
Fly Mating Behavior:
QuickTimeTM and a Cinepak decompressor are needed to see this picture.
Chase Sing Lick Mount
Multiple sensory cues involved.
What controls whether cues are attractive or repulsive?
http://www.cshprotocols.org/cgi/content/full/2007/20/pdb.prot4847
Scientific Method: Observe
Authors observed homosexual interactions when genderblind was mutated:
QuickTimeTM and a decompressor are needed to see this picture.
QuickTimeTM and a decompressor are needed to see this picture.
Normal Males
Mutant Method: Males
Scientific Hypothesize
When genderblind is mutated, male flies engage in homosexual copulation more frequently. Phenotype
genderblind
Hypothesis: genderblind controls fruit fly courtship
www.physics.arizona.edu/~skinner/i
Homosexual Behavior:
Phenotype
Genderblind Mutation:
Genotype
Scientific Method: Experiment
How do we know gene mutation = phenotype?
RNAi
Phenotype
genderblind
By silencing the RNA, scientists could induce homosexual interactions in as little as two hours.
Scientific Method: Experiment
Can we rescue the phenotype?
Phenotype
Drugs ( -DBB)
No Phenotype
genderblind
When drugs were administered to mimic the effects of the Genderblind protein, homosexual behavior was not observed.
Experimental DesignThings to Consider
Experimental Controls: Large sample of flies analyzed Clonal population of flies (MZ) Everything is compared to wt Blind analysis
The Laboratory is a highly controlled environment
Reproducibility: Methods carefully documented Experiments conducted 3X
Correlation = Causation
Scientific Method: Analyze
Need a way to quantify behavior:
Results must be quantified to determine significance
genderblind
Genotype Phenotype
Mutate a single gene and change a complex behavior...
Do we play by the same set of genetic rules?
Find millions of documents on Course Hero - Study Guides, Lecture Notes, Reference Materials, Practice Exams and more.
Course Hero has millions of course specific materials providing students with the best way to expand
their education.
Below is a small sample set of documents:
Below is a small sample set of documents:
Vanderbilt - HUM - 161
Notes Thursday 1/29/081. Survey Research a. Professors liked it b. Taught their students c. New generation used surveys d. 2. Science a. Self correcting b. Always getting better c. Always comes up with new things 3. 1987 a. News that matters b. Iye
St. Johns - BIO - 3000
CHAPTER 45 NEUROSCIENCE III: SENSORY SYSTEMS1 Sensory transduction Incoming stimuli (chemical or physical stimuli from an animal's body or the external environment) are converted into neural signals Perception Awareness of sensations Not all
Georgetown - ECON - 001
Think Like An EconomistObjectivesToday's Lecture: Competitive Markets Demand Supply Market EquilibriumMarkets and PricesMarkets are where buyers and sellers meet to exchange goods and services- Exchange information and do business.Can
Georgetown - HIST - 286
Germantown protest-first antislavery movement Spontaneous anti slavery of slaves themselves (rebellions and revolts) Feeling not just that I shouldn't be a slave, but that no one should be a slave (conceptual leap) Sources-religion, radical strand pr
Georgetown - ECON - 001
Welcome Economist!Lecture 5 ObjectivesToday's Lecture: Efficiency Consumer Surplus Producer Surplus Deadweight LossSelf-Interest and the Social InterestPurchases - expression of how scarce resources should be usedChoices are made in your
Georgetown - ECON - 001
Think Like An EconomistObjectivesToday's Lecture: Production possibilities Scarcity, Opportunity Cost, Trade-Offs Marginal Cost Production GrowthUnlimited Wants - Limited ResourcesAllocating Scarce ResourcesModel:Assume 2 goods Hold the
Georgetown - ECON - 001
ObjectivesMonopolies!Market Structure: Perfect Competition1. Free Entry/Exit2. Perfect Information3. Homogenous Products 4. Price taker No Market Power5. Efficient outcome6. P=MR=MC 7. Long-run Economic Profit is Zero 8. Produce at the Mi
TAMU Commerce - ART - Art 3D Des
During my spring break I went to the Museum of Modern and Contemporary Art in Geneva, Switzerland. The collections displayed were nothing short of spectacular. A certain piece that caught my eye was from Robert Filliou titled "Eins. Un One.". Origina
GCSU - POLS - 1150
Public Opinion, Voting, and ElectionsReference: Ch. 6Public Opinion Public Opinion has become more important over timein politics "Myth of the Popular Will"; Andrew Jackson and the "Common Man," Trends toward direct democracy Public Opinion
GCSU - POLS - 1150
The Executive Branch: The PresidencyRefer to Chapter 9 in MaglebyOverview of the Presidency Intentions of the Framers regarding the Executive Branch and the Presidency Structures and Powers Evolution and Trends of the Office Managing the
GCSU - POLS - 1150
The Legislative Branch: CongressRefer to Chapter 8 in MaglebyOverview of the Legislative Branch 2006 Congressional Elections The Framers and Article 1 of the Constitution Congress' role in the three branches of gov't Dual Functions of
GCSU - POLS - 1150
Judicial Branch: Ch. 11 in MaglebyQuestions: What are the functions of the judicial branch? Characteristics? How does the judicial branch interact with the other branches and how do other branches interact with judicial branch? What is the structure
GCSU - POLS - 1150
Political Parties and Interest GroupsCh. 5Political PartiesDefinition: coalitions of individuals and groups that seek to influence gov't by getting their candidates elected to office How are they different from interest groups?Political Parties
GCSU - POLS - 1150
Georgia GovernmentOverview of Georgia Government at the State and Local LevelsThe Importance of State and Local Governments Americans trust local and state government more than the national government U.S. has more than 87,000 units of Governmen
GCSU - POLS - 1150
Study Guide Exam 2Chapters 5, 6, 8, 9 USE YOUR NOTES, CLASS LECTURES, AND TEXT TO DEFINE, IDENTIFY, ANALYZE, EXPLAIN THE SIGNFICANCE OF, AND PROVIDE AN EXAMPLE OF THE FOLLOWING:1. Chapter 5: Political Parties and Interest Groups Vocab U.S. as a tw
Colgate - CORE - 152
In volume I, chapter III, page 32, Victor Frankenstein remarks on the excitement and enthusiasm proposed in his desire to be a creator. "Life and death appeared to me ideal bounds, which I should first break through, and pour a torrent of light into
Colgate - CORE - 152
Rashonda K. Core 152 Prof. M. Burczyk T 11.09.07 1. One of the topics we addressed in Monstrous Eve by Sandra M. Gilbert and Susan Gubar was Victor's transformation from an Adamic figure to a Satanic figure. We agreed that the story of Lucifer and Go
Colgate - ENGL - 242
Tess of the d'Ubervilles: A Life Paid in Blood Blood is the vital fluid of the human body. It is also a term used to describe the genetic relationship between members of the same family. While both usages of the term imply a sort of continuity, of li
Colgate - ENGL - 242
The Romantic Period 1785-1830 a mode of literature associated with the Middle Ages and the Renaissance (A.W. Schlegel - critic - Romaniticism) revolutionary-> changed the way of writing turns away from optimism of the Enlightenment all human being ar
Colgate - ENGL - 242
The Victorian Age 1830-1901Repressed, prudish, kinky argument and persuasion Socioeconomic changes. Consumerist, materialist culture Discourse more accessible. Middle brow conformist culture. Writing in the rise of the middle class Mood of incremen
Colgate - SOAN - 101
GENDER, RACE & CLASS Invisible Inequality. Social Class and Childrearing in Black Families and White Families Lareau shows how social class affects parenting styles among both white and black families. Upper middle class family (concerted cultivation
Colgate - CORE - 152
Reading "Maus" was a very interesting experience for me. Mostly, I forgot that I was reading about events happening to actual people. Other times, I forgot that these people were portrayed as mice. The idea of portraying the Jews as mouse seems to ma
Colgate - SPAN - 354
23 de mayo de 1981 Seor Conrado Sosa-Palomar: El Comit de Premios ha recibido su carta y la considerado. Puede ver como usted llegara a sus conclusiones pero piensa que haya un error en su entendimiento de los cuentos y de las intenciones de los auto
Colgate - RELG - 246
Where Im Coming From Hello and good afternoon. I am Professor [nameomitted] and today I will be speaking on the development of Black feminism and its connection to American politics and Caribbean life. I will begin by addressing colonialAmerican
Colgate - CORE - 151
The Tragedy of OrpheusThe story of Orpheus is a tragic one. Unlike many of the other characters, all of his misfortunes are due to the actions of other people and not directly by the gods. His horrible fate was not due to impiety or pride and begin
Colgate - CORE - 151
1How has the role of the prophet changed? How is the prophet received? How is the prophecy received? How is the prophecy fulfilled?The Role of the Prophet/ Dream Interpreter Throughout time, the role of the prophet and dream interpreter has been
Colgate - FSEM - 129
Alan Mathison Turing was born June 23, 1912 in England.1 His father, Julius Turing, born November 9, 1873,2 was second son of John Robert Turing.3 As a result, Julius had become an officer of the Indian civil service and was still employed at the tim
Colgate - SOAN - 101
Notes for Monday 3 March 2008 Finishing up what we discussed on Wednesday 27 March 2008 -Socio-economic status (SES) is more complex than money. It needs to take into account power, networking, societal status and privilege. -"code-switching" relates
Colgate - CORE - 161
Assess the contributions of Marcus Garvey and W. E. B. DuBois to the Pan-African movement. Despite the seemingly oppositional lives of Marcus Garvey and W. E. B. DuBois, the actions and politics of both men gave strength and support to the Pan-Africa
Colgate - ENGL - 206
1The Governess's Life: James's True Ghost Story When Henry James was asked to write a ghost story, he thought of a story he had heard of two children terrorized by a ghost in an old country estate. The ending result of the story was James's The Tur
Colgate - SPAN - 361
Belle poque: la idiotez de la vida amorosaFernando es un hombre joven que desert el ejrcito con la esperanza de volver a Madrid. Mientras su viaje, encontr a un hombre viejo quien se llama don Manolo . Don Manolo es un hombre que lament su capacida
Colgate - SPAN - 361
tame! el papel de la mujer en las fantasas de los hombres A primera vista, la pelcula tame! parece ser una historia sobre del triunfo de amor durante circunstancias extraas. La pelcula sigue el progreso del amor entre Marina, un actriz de cine "porno
Colgate - SPAN - 361
Pepa Marcos es una mujer que tiene mucho xito en su trabajo. Ella es actriz de doblaje por las pelculas adems de tener un papel famoso como la madre del "Asesino de Cuatro Caminos". Su xito permite que ella tenga un apartamento grande con una terraza
Colgate - EDUC - 101
Educational Policy: The Culture of Fear and the Politics of Education The purpose of the American public school system is to justly educate children in American society and to create good citizens. While this may have been the original principle, the
Colgate - SPAN - 361
La amistad preciosa entre fresa y chocolateEste es un relato como dicho al taxista por Diego. l est en un taxi en ruta al aeropuerto para que volar a Miami y est reflexionando en los eventos interesantes que precedieron su destierro. Al principio d
Colgate - EDUC - 101
It seems parents in the Brentwood, NY area are taking a page out of John Locke's book on the theory of education; younger children are now learning at home with their parents. Well, not exactly. The Parent-Child Program "aims to foster literacy and t
Colgate - EDUC - 101
The Government's Problem with DIY Education California is throwing around all types of - let's say interesting - legislation lately. After recently prohibiting smoking in a car while a minor is present, they have now moved from what people can do in
Colgate - EDUC - 101
A quiz implemented by an organization known as the Common Core has left 17year olds across the country stumped. In January, Common Core contacted about 1200 17-year olds to ask them 33 multiple choice questions about history and literature. The No Ch
Colgate - SPAN - 354
A primera vista, los cuentos "A la deriva" y "Los inmigrantes" parecen ser sobre los momentos finales en las muertes de los personajes pero en realidad, Horacio Quiroga cambia sus temas complejos con su lengua comn y una historia engaosamente sencill
Colgate - SPAN - 354
Rashonda Kinnard Span 354 Prof. F. Luciani 08.10.07 Los escritos de Sor Juana muestran como las personas pueden ser engaadas por sus sentidos, es decir, lo que parece ser no es lo que es en realidad. En sus sonetos 145, 152, 164, y 165, Sor Juana sie
Colgate - CORE - 152
There is perhaps no psychic phenomenon which is so unconditionally reserved to the city as the blas outlook. It is at first the consequence of those rapidly shifting stimulations of the nerves which are thrown together in all their contrasts and from
Colgate - CORE - 152
The free intellect copies human life, but it considers this life to be something good and seems to be quite satisfied with it. That immense framework and planking of concepts to which the needy man clings his whole life long in order to preserve hims
Colgate - CORE - 152
1. Marx & Engels would not have approved of our current globalized world. In fact, this passage views the globalization and socio-economic interdependence of nations as a tool of the bourgeoisie. "In place of the old local and national seclusion and
Colgate - CORE - 152
In our investigations and our therapy of the neuroses we cannot avoid finding fault with the super-ego of the individual on two counts: in commanding and prohibiting with such severity it trouble too little about the happiness of the ego, and it fail
Colgate - CORE - 152
1. The noble science of Geology loses glory from the extreme imperfection of the record. The crust of the earth with its embedded remains must not be looked at as a well-filled museum, but as a poor collection made at hazard and rare intervals. The a
Colgate - CORE - 152
Gyula Halasz Brassa's "Young Couple" was one of my favourite photographs in the gallery. It was taken in 1932 and the focus of the photo is a homosexual male couple, dancing among the other couples. There are two other couples in the background on ei
Colgate - CORE - 152
1. The fat girl in the story conjures feelings of disgust and general disdain for the narrator. The girl, who we later find out to be the narrator herself at a younger age, is not described in a flattering manner at all. The way the narrator presents
Colgate - SOAN - 101
Hang Up the Hook-Up On Thursday, April 3, Bring Back the Date, SYE, and the Wellness Initiative hosted guest speakers John-Michael Scott and Amy Segner, two dating specialists. The two speakers both boast a commitment to helping others achieve dating
Colgate - SOAN - 101
Michael Eric Dyson "From Sit-ins to Hip-Hop: Social Consciousness in a Post-King America" The lecture, hosted by Brothers, took place the night of Tuesday 12 February at 7pm in Love Auditorium. Michael Eric Dyson is an ordained minister as well as a
Colgate - ENGL - 206
When William Blake published Songs of Innocence and Experience in 1794, he included a subtitle explaining that the work was shewing the two contrary states of the human soul. Upon examination of Lyrical Ballads, one could argue that William Wordswort
Colgate - EDUC - 101
Unesco Panel to Ponder the Challenge to Education of Creating a New HumanismBy Barry James Published: WEDNESDAY, FEBRUARY 17, 1993PARIS: The population explosion. Violence. Intolerance. Ethnic conflict. The deteriorating environment. Is history, a
Colgate - EDUC - 101
The New York Times' ran an article about West Virginia University's investigation into the authenticity of Heather Bresch's degree. Heather Bresch is the daughter of West Virginia's governor, Joe Manchin III. The university only decided to investigat
Colgate - EDUC - 101
Schools in Perth Amboy, New Jersey are in for a rude awakening. The schools were once in such bad shape that the teacher-student ratio was closing in on 1:35. Overpopulated and under-funded, these schools were going down and taking everyone involved
Colgate - EDUC - 101
In Georgia, a group of third-graders plotted to attack their teacher. At first, the entire sentence seems like one big joke. Surely they must've been playing some sort of game or this is a strange introduction to some play that the children were invo
Colgate - EDUC - 101
An article published in the International Herald Tribune last summer addresses Justice Clarence Thomas' controversial view, and rulings, on integration and affirmative action. Thomas voted against school integration plans in Seattle and Louisville, K
Colgate - SPAN - 352
La sociedad del siglo XVII era una de machisma y los derechos superiores de los hombres. Las mujeres de ese tiempo tenan menos derechos de los hombres. No les fue permitido leer ni escribir. El pensamiento aceptado por la sociedad era lo que diga que
Colgate - SPAN - 352
En los tiempos del Renacimiento y del Barroco, los poetas escribieron sobre los amantes y los amores usando los estilos contemporneos del tiempo. A veces, describieron el amor tpico, el rostro ideal de la mujer y tambin la dedicacin religiosa con poe
Colgate - SPAN - 352
Los pecados del padre. La relacin entre los padres y los hijos es muy importante en el mundo. Usualmente, los padres crecen y cuidar a los hijos y tienen la mas influencia en las creencias, las actitudes, y las acciones de los hijos. En la obra Del r
Colgate - CORE - 152
The Truth, the Whole Truth, and Nothing but the. truth, n. the quality of being true. When I was about 11 or 12 years old, I went to a magic show. The magician there was quite normally dressed, I guess, as far as magicians go. He wore a black suit, w
Colgate - CORE - 152
Since the time when we recognized the error of supposing that ordinary forgetting signified destruction or annihilation of the memory-trace, we have been inclined to the opposite view that nothing once formed in the mind could ever perish, that every
Marquette - HIST - 002
History 2 Western Civilization 2Century Thought & CultureThe revolutions of the 1830's removed the conservatives from power and brought in those who wanted change. The king was denounced and a new government was put into place. The people revolted