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Most commonly associated with reheated rice dishes

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most commonly associated with reheated rice dishesVaccine:No Vaccine, most illness is self-limitingNote to SelfCheck out the warning signs on take out containers of mostlarger Chinese restaurants.Clostridium tetaniDisease:Tetanus or lockjawRoute of Transmission:Puncture woundNote to Self
7/24/22, 10:43 PMfiles/softchalk/bacterialdiseases2019/bacterial…files/softchalk/bacterialdiseases2019/bacterialdiseases2019_print.…67/83Remember this disease has nothing to do with rust or rusty nails.Symptoms:the organism reaches the anaerobic environment it prefers afterpuncture wound72 hours with headaches, fever, irritability and paralysis of faceand necksevere disease noted by muscle spasms and convulsionsendospores widespread in soil, produces a neurotoxin calledtetanospasmin (LD50 = 20ng) which causes spastic paralysisconvulsive contractions of voluntary musclesdeath results from spasms of respiratory musclesVaccine:Immunization byDPT(Diphtheria, Pertussis and Tetanus)includestetanus toxoid(inactivated toxin), booster is often given, ifyou have never been immunized before, tetanus immune globulin isgiven,Debridement(removal of tissue) and antibiotics may benecessary to clear the organismsClostridium botulinum
7/24/22, 10:43 PMfiles/softchalk/bacterialdiseases2019/bacterial…files/softchalk/bacterialdiseases2019/bacterialdiseases2019_print.…68/83Disease:botulismRoute of Transmission:Ingestion of toxin or bacilliSymptoms:caused by ingesting preformed exotoxin which is destroyed byproper boiling ( an intoxication, not a true infection)Symptoms include nausea, diplopia (double vision) anddysphagia (difficulty in swallowing)toxin is acid stable and survives stomach, Toxin is heat labileacts at neuromuscular junctions by inhibiting acetylcholine releaseso nerve impulses are blockedblurred vision occurs within the first 1-2 daysfollowed by flaccid paralysis and often death due to respiratoryfailure as a result of paralysis of the diaphragm.Wound botulism may also occur when the organism growsanaerobically in deep wounds.Vaccine:Treatment is antitoxin, Supportive therapy essential, Until1993, the U.S. Army Medical Research Institute of InfectiousDiseases (USAMRIID) kept one horse named First Flight and injectedhim with 7 serotypes of botulism toxoid. He was the United Statesonly source of heptavalent botulinum antitoxin and donated more than1,600 liters of blood during his duty. He was the only source ofantitoxin for our troops during the Gulf War when Saddam Husseinhad botulism in his germ warfare arsenal. First Flight has now beenretired.

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Syphilis

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