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3+Connective+tissue - Online Histology BIOL 128 3:...

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Online Histology BIOL 1283: Connective tissueConnective tissue (CT), as the name suggests, connects other tissues together and providesstructural and functional support. For example, if you consider your upper arm, you'll find thehumerus, a number of muscles, blood vessels, nerves, and lymphatic vessels. Surrounding all of themand filling any gaps that would exist between them is CT, thereby providing structural support. CTfacilitates the movement of nutrients, gases and other substances between tissues, thereby providingfunctional support.Definition of CTCT is defined as a collection of specialized cells in an extracellular matrix. Compare with epithelialtissue, in which cells exist on a surface, not in a surrounding matrix. CTs range from mineralized solid(bone) to liquid (lymph and blood).Classification of CTThe classification of the various CTs in the body is a little vague. You'll see different classificationschemes in different texts. As far as we're concerned in this course, there are two major categories(CT proper and Specialized CT) and then a variety of other types, all listed below.CT proper1. Loose CT, also known as areolar CT2. Dense CT, divided into dense regular CT and dense irregular CTSpecialized CT1. Cartilage and bone, known as supporting specialized CTs2. Blood and lymph, known as fluid specialized CTsOther CTs1. Embryonic CT (Mesenchyme, Wharton's jelly, Mucous CT)2. Adipose tissue3. Reticular tissue4. Hematopoietic tissueAs mentioned above, all of these varied tissues are properly categorized as connective tissuesbecause they consist of a collection of specialized cells in an extracellular matrix. For example, thespecialized cells of blood are red and white blood cells and the extracellular matrix is plasma. In bonetissue, the specialized cells exist in spaces within an extracellular matrix that has become mineralized.We'll look at the various specialized CTs in detail in the coming weeks, but for the moment, we'llconcentrate on CT proper.Functions of CT- Structural support (bone, cartilage, tendons, ligaments, stroma).- Functional support (medium for exchange).Connective tissue properCT proper is split into two categories, loose and dense. Loose CT is more properly known as areolarCT. In both areolar CT and dense CT, the matrix consists of an amorphous (shapeless) hydrated gel,known as ground substance, and fibers.Fibers of the extracellular matrix of CT properThere are three kinds of fiber; collagen, elastic and reticular. All three are present in the groundsubstance of areolar CT, but only one fiber is found in the ground substance of dense CT.
Collagen fibersThere 28 types of collagen, but we only need to be familiar with Type I and II. Type I is found incommon tissues, such as areolar CT, bone, cementum, dentin, skin and fibrocartilage. Type II isfound in hyaline cartilage and elastic cartilage.

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Term
Spring
Professor
JoannaS.Albala
Tags
cells, Collagen, Mesenchymal cells, Collagen fibers

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