This preview shows pages 1–3. Sign up to view the full content.
This preview has intentionally blurred sections. Sign up to view the full version.View Full Document
Unformatted text preview: Cl O CHEM 317 PS 3 Ethers and Epoxides-Solutions 4. O H + O H + H 2 O O OH HO OH S H 2 O H H acid-catalyzed O base OH O OH H O H HO OH + -OH (+H + ) Acid catalyzed involves attack at the chiral carbon and gives inversion of configuration. For the base catalyzed opening, no bond to the chiral center is broken and the configuration is retained. R R R...
View Full Document
- Fall '08