Valerie_King_Unit 9 Assignment_Diseases Of The Human Body.pptx

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Valerie KingHS200Diseases Of The Human Body1901B January 2019 TermDr. Jayasri Ghosedastidar
The Etiology of CancerTransformationAbnormal GenesAn error in the cell occurs that instructs the cell to grow and divide, the loss ofnormal cell control causing rapid division and growth of the cell.Failure to stop uncontrolled cell growth mutation in gene allows cancer cells tocontinue growing and accumulating.Initiating causes of Cancer, are called carcinogens.Chemical- Cigarette biggest factorOncogenic virusesRadiation
The Etiology of Cancer: Oncogenic VirusRNA- and DNA both contain Oncogenic virus which have tumor-producingpotentialCervix cancer is caused by viruses.Tumor causing virusesEpstein-Barr virus, Herpes simplex type-2 virus are called oncoviruses.
The Etiology of CancerProto-OncogeneProto-oncogenes are involved in normalcell growth and division mutationcauses themto grow rapidly whichmakes cancer-causing genes oroncogenesTumor suppressor genescontrols cell growth and division,mutation in the cells causing genes todivide grow uncontrollablyDNA repair genesThese genes are involved in fixing damaged DNA,mutations in these genes cause more mutations inother genes causing cancer cells.Inherited Genetic Mutation Inheritedgenetic mutation causesfaster development ofcancer in affected individualsBRCA1 and BRCA2 are Inheritance defectivetumor suppressor genes responsible for mostfamilial breast and ovarian carcinomasGermline mutation of the oncogene p53responsible for neoplasms This mutation can befound in the thyroid, stomach, breast, and softtissues
Breast CancerBreast cancer develops when certain cells in thebreast become abnormal and multiplyuncontrollably to form a tumor.Breast cancer is commonly found in women,Men can also have breast cancerBreast cancer in women, can develop in theglands that produce milk (lobular cancer), themost common form of breast cancer bothwomen and menbegins in cells lining the milkducts because men have little or no lobulartissue, so lobular cancer in men is very rare.Breast Cancer. Genetics Home Reference.Retrieved fromRisk FactorsGenetic changes can cause breast cancer, research has foundthat hormonal, lifestyle and environmental factors mayincrease the risk of breast cancer.A personal history of breast cancerBRCA1 or BRCA2 gene mutationBeing obese increases the risk of breast cancer.Drinking alcohol increases the risk of breast cancer.Having never been pregnant or having children at an olderageEthnic backgroundMayo Clinic. Breast cancer. Retrieved from-cancer/symptoms-causes/syc-20352470
Breast Cancer : Risk FactorsGenetic changes can cause breast cancer, research has found that hormonal,lifestyle and environmental factors may increase the risk of breast cancer.

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