NE101 Computational Neuroscience notes

NE101 Computational Neuroscience notes - Computational...

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12/3/12 Computational Neuroscience What is consciousness? “my fundamental premise about the brain is that its wprkings, which we sometimes call the “mind” are a consequence of its anatomy and physiology and nothing more” -Carl Sagan “replicate a brain” -program a comp. to stimulate all mechanisms of a brain -Biology (neurons, synapses, ion channels) -Program acomp to achieve the functions of the brain (when I see a lion, I run) In comp Neuro we try to address issues like thes: How do we model the brain? How does the brain implement functions? Interdisciplinary: Wet sciences: Neuro, bio, chem, med Dry sciences: math, comp sci, eng Physics: math descriptions of the world “computational” perspective -“all science is either physics or stamp collecting” Ernest Rutherford There is a meaningful mathematical mode/description permittin experimental predictions, deeper understanding, and endless experimental “Basically, the theorist is a lazy person masquerading as a diligent one” -Santiago Ramon y Cajal
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Unformatted text preview: Inclusive Philosophy Three pronged approach to computational neuroscience-Date-Analysis-Models They are interrelated-data to motivate models-models (ideally) The “computation” 1. Motivation a. Computation in the world motivates/frames our understanding b. Ex. The brain c. The brain and comp can perform similar operations d. The nervous systems lacks a systemwide clock e. The nervous system is built from stochastic elements f. The brain is constantly reprogramming itself, as function of input g. As a network: social networks, infrastructure networks, biological networks A network has two components Nodes Edges (connect nodes) Two classes of brain networks: structural and functional Functional networks evolve with time 2. Data 3. Modeling a. Right scale b. How do make sense of such a complicated model c. What if we build a model that’s as complicated as the brain itself Comp Neuro involves many different things What cause brain diseases? How can we fix them and prevent them?‘...
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  • Fall '12
  • PaulLipton
  • comp neuro

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