Test Fileto accompanyLife: The Science of Biology,Ninth EditionSadava • Hillis • Heller • BerenbaumChapter 15: Gene Mutation and Molecular MedicineTEST FILE QUESTIONS(By Catherine Ueckert)Multiple Choice1. Mutations area. heritable changes in the sequence of DNA bases that produce an observable phenotype.b. changes in the nucleotide sequence of DNA that is passed on from one organism to another.c. mistakes in the incorporation of amino acids into proteins.d. heritable changes in the mRNA of an organism.e. None of the aboveAnswer: bTextbook Reference: 15.1 What Are Mutations?Page: 317Bloom’s Category: 2. Understanding2. Somatic and germ line are two types of mutations found in multicellular organisms. Which of the following is a true statement regarding these two types of mutations?2. Understanding3. In sickle-cell disease, one amino acid is substituted for another. This type of mutation is referred to as a _______ mutation.
1. Remembering4. Silent mutations have no effect on amino acid sequences. This is due to the fact that2. Understanding5. The type of mutation that involves the insertion or a deletion of a single base in the coding region of proteins is calleda. a missense mutation.b. a nonsense mutation.c. a point mutation.d. an aberration.e. None of the aboveAnswer: cTextbook Reference: 15.1 What Are Mutations?Page: 318Bloom’s Category: 1. Remembering