Exam3StudyQuestions_ver1_040914 - EXAM 3 STUDY QUESTIONS(version 1 The questions on the third hour exam will be based on those given below If you can

Exam3StudyQuestions_ver1_040914 - EXAM 3 STUDY...

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EXAM 3 STUDY QUESTIONS (version 1, 04/09/14) The questions on the third hour exam will be based on those given below. If you can answer the questions here, you should have little trouble with the exam. [Note: These questions are meant to provoke thought and study. As before, do not ask Dr. Sokolove or the TAs to provide you with the answers.] 1. What was Crick’s “adapter molecule” and how was it discovered? What is an “anticodon”? 2. How many different codons are there (Chap 16)? How many different anticodons are there? [Hint: How many types of tRNA are there?] Explain what accounts for the difference.3. There must be at least _?_ different “aminoacyl tRNA snythetases.” What do these enzymes do? What would be the effect of a mutation in the gene for a particular aminoacyl tRNA synthetase that caused the enzyme to recognize lysine if the unmutated synthetase recognized theamino acid serine? 4. What are the three phases of protein synthesis (translation)? Briefly describe each phase.5. How do mRNAs and ribosomes get together to start the process of translation in bacteria? In eukaryotes?6. What is a “ribozyme” and how do we know that a ribozyme catalyzes peptide bond formation?7. How does protein synthesis conclude when a ribosome reaches the end of the translated region? Is the process different in bacteria and eukaryotes? If so, how do they differ?8. What processes take place afterthe translation of mRNA into a linear sequence of amino acids(i.e., into a polypeptide or protein) has been completed? In addition to protein folding and attachment of small chemical groups (such as sugar-based sorting signals), describe at least one other type of post-translational process. ---------------------------------------------
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