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Quiz 4 Key - Name Quiz 4 BIMM 110 1 Provide a rough diagram...

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Name_________________________________________________ page 1 Quiz 4. BIMM 110 1. Provide a rough diagram of the structure of a T-cell receptor, including the position of the hypervariable binding regions in the receptor, and the position of receptors in the cell. (3 pts) A dimeric protein diagram, no matter how crude, (something that looks like a Y shaped antibody is NOT OK), crossing the plasma membrane, with antigen binding sites in a distal, extracellular position on the drawing of the receptor. 2.What is the ligand or molecular "signal" on the surface of a virally infected cell that instructs a cytotoxic T- cell to secrete perforins? (3 pts) An MHC protein in a complex with a peptide antigen derived from processed viral proteins. 3. Why does HIV infect and destroy helper T cells and not B-lymphocytes? (2 pts) Helper Ts have CD4 receptors on their surface 5.Describe the molecular recognition process in the thymus that prevents cytotoxic T-cells from eventually killing your liver cells. Do NOT describe all the recognition processes that take place during T cell maturation.
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