Week 6 Case study -Describe the bone cells that are involved in generation of bone tissue. There are 4 primary bone cells that are responsible for generation of bone tissue. These cells are called: osteogenic cells, osteoblasts, osteocytes, and osteoclasts. Osteogenic cells are the only cells that divide and are the stem cells of the bone cells. Osteogenic cells will differentiate into bone cells such as osteoblasts and osteoclasts. Osteoblats are responsible for synthesis of bone formation from organic matter and this process is called osteogenesis. Ostecytes are cells that are deposited and trapped in the cellular matrix and mature osteoblasts. Osteocytes act as strain senors and will produce biochemical signals that are responsible for regulation of bone formation and remodeling. Osteoclasts are the cells responsible for the breakdown and reabsorption of bone. Osteocalts carry out bone-dissolving functions and are also essential in bone remodeling along with osteoblasts.
