Emilys_chap7-12_review

Emilys_chap7-12_review - AIDS FUNDAMENTALS REVIEW BOOK...

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AIDS FUNDAMENTALS REVIEW 04/12/2007 18:26:00 BOOK REVIEW CHATPER 7       Biological Basis of HIV Transmission -Virus is quite fragile in the external environment Sources of Infectious HIV -Macrophages, Langerhans cells and T helper lymphocytes are susceptible to the HIV  virus -Macrophages are found in the mucosal linings of the body (surface of vagina, penis,  anus, lungs, throats) Targets for HIV Infection -The receptor for HIV is the CD-4 surface protein, which is present on T helper  lymphocytes, macrophages, and the Langerhans cells. -Located in the blood, the mucosal surface, oral cavity and the throat Degrees of HIV Infectivity -Group 1: very high infectivity- blood semen, vaginal/cervical secretion (including  menstrual) -Group 2: high infectivity- breast milk -Group 3: low infectivity- saliva, tears -Group 4: no infectivity- perspiration/sweat, urine, feces Modes of HIV transmission  -Transmission requires direct contact of two substances: containing HIV from an infected  person and susceptible cells (usually via the bloodstream) of another person BIRTH -The child frequently comes into close contact with the mother’s cervical vaginal  secretions or blood due to bleeding associated with delivery.  BLOOD TRANSMISSION
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-Receiving a transfusion of infected blood or by injection with a HIV contaminated  syringe -Have to analyze the potential of infected blood -Needles are shared during injection drug use and through accidental needle sticks b/w  am HIV infected individual and a health worker -Risk of contracting HIV from a contaminated needle stick is 1 in 200  (one half of a  percent) SEX -HIV infected blood, semen, or cervical vaginal secretions from an infected person come  in immediate and direct contact with the bloodstream or mucous membranes of another person.  -Because we know that saliva of an HIV infected person contains little, if any, HIV, so  there is not a likely source of infection. Oral sex performed on an HIV infected man or women by  either a woman or man has not been strongly associated with HIV transmission CHAPTER 8     Individual Decision Making -Four steps: knowledge, attitude, intention, behavior Risk Assessment     -Two types: normative model, subjective model -Probalistic information contains an estimate related to an issue or topic - Normative Model:  probability information is weighed according to statistical rules to  reach conclusions.  -Subjective Model:  “judgment heuristics” -Judgment heuristics:  these are rules of thumbs, identifies in a variety of research 
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This note was uploaded on 04/13/2008 for the course BIO SCI 45 taught by Professor Pickus during the Winter '08 term at UC Irvine.

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Emilys_chap7-12_review - AIDS FUNDAMENTALS REVIEW BOOK...

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