Antibiotics - Antibiotics Infection - invasion of body by...

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Antibiotics Infection - invasion of body by pathogenic microorganisms that reproduce to causes disease Bactermia: variable bacteria in blood Sepsis - multiple system organ involvement syndrome Septicemia - systemic infection w/ pathogens in bloodstream Colonization - localized presence and multiplication of microoganisms w/o invasion or damage PENICILLINS Type Drug Spectrum: Indications: ADRs: Natural Penicillins ***Gm+ activity penicillin G, penicillin VK oral drugs procain pen G gonorrhea benzathine pen G syphillis, strep throat **penicillins not used much anymore b/c penicillinase-resistant --> work against Gram + organisms Penicillinase-Resistant ***Gm+ only - CILLIN metha-, oxa- naf- most active, best CNS penetration dicloxa-, cloxa- best at oral absorption ****the only penicillins that are resistant to penicillinase are penicillinase-resistant penicillins Aminopenicillin ***some Gm- including H.flu and E.coli ampicillin diarrhea, rash amoxicillin better absorption less GI problems
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This note was uploaded on 04/07/2008 for the course PHARM 338 taught by Professor Karboski during the Fall '07 term at University of Texas.

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Antibiotics - Antibiotics Infection - invasion of body by...

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