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21 - Prolactin can speed up tail regeneration in lizards...

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3-21-08 Prolactin can speed up tail regeneration in lizards Injection of melatonin can cause increase growth. (recall dopamine inhibits PRL secretion) Prolactin seems to working like a growth hormone Growth Hormone Most Mn Ghs work in non-mammals and vice-versa Comparative functional studies are clouded by similarities of actions with PRL (similar structure) For ex, PRL promotes growth in larval amphibians. A Phylogeny of growth Hormones #’s of a.a in the chain per hundred Bspace Suggest that most of th teleosts have branched from Chrocodilians and birds make a sub cluster from the other others GH has been extracted from sea lampreys which cause ____ production from the liver GH is the most primitive in the category of hormones and PRL possibly appeared from gene duplication. GH also being identified in Hagfishes None however identified in _____________ PRL and GH in Agnathans and Chondrichthyeans Long believed that agnathans did not posses PRL (only vertebrates that don’t) Bioassay said to produce positive effects from lamprey pituitary, but conflicting reports: - Sage M, Bern HA (1972) Assay of prolactin in verterbrate pituitaries by its dispersion of xanthochroid pigment in the teleost Gillichthys mirabilis. J Exp Zool. 180: 169-74 This is the long jawed blood sucker Extremely sensitive to non-_______ PRL which causes the yellowing of the eye In this paper some fish had been responding to lamprey PRL and some didn’t so inconclusive.
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