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Unformatted text preview: 3-21-08Prolactin can speed up tail regeneration in lizardsInjection of melatonin can cause increase growth. (recall dopamine inhibits PRL secretion) Prolactin seems to working like a growth hormoneGrowth HormoneMost Mn Ghs work in non-mammals and vice-versaComparative functional studies are clouded by similarities of actions with PRL (similar structure)For ex, PRL promotes growth in larval amphibians.A Phylogeny of growth Hormones#s of a.a in the chain per hundredBspaceSuggest that most of th teleosts have branched from Chrocodilians and birds make a sub cluster from the other othersGH has been extracted from sea lampreys which cause ____ production from the liverGH is the most primitive in the category of hormones and PRL possibly appeared from gene duplication.GH also being identified in HagfishesNone however identified in _____________ PRL and GH in Agnathans and ChondrichthyeansLong believed that agnathans did not posses PRL (only vertebrates that dont)Bioassay said to produce positive effects from lamprey pituitary, but conflicting reports:-Sage M, Bern HA (1972)Assay of prolactin in verterbrate pituitaries by its dispersion of xanthochroid pigment in the teleost Gillichthys mirabilis. J Exp Zool. 180: 169-74This is the long jawed blood suckerExtremely sensitive to non-_______ PRL which causes the yellowing of the eyeIn this paper some fish had been responding to lamprey PRL and some didnt so inconclusive....
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- Spring '08