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Unformatted text preview: ANXIETY DISORDERS AND INSOMNIA anxiety- normal emotion state in response to a stressful situation Spectrum: GAD, panic disorder, SAD, PTSD, OCD goals: reduce severity, duration, and frequency, improve daily functioning, prevent relapse, improve QOL Treatment Type Drugs Used as MOA ADRs: Non Pharmacologic - psychotherapy, patient education Pharmacologic Antidepressants **1st choice SSRIs bocks serotonin reuptake GI effects, insomnia, weight changes, effective in pt with depression tremor, sexual dysfunction, initial anxiety fluvoxamine SNRIs venlafaxine Blocks reuptake of nausea, vomiting, somnolence, increase duloxetine serotonin and NE in blood pressure Buspirone BuSpar **2nd choice used for ????/ dizziness, nausea, headaches **no abuse potential Benzodiazepines used for ACUTE symptoms CNS depression, confusion, aggression - ZEPAM clona-, dia-, lora-, oxa- excitement, anterograde amnesia alprazolam, clorazepate, chlodiazepoxide **ABUSE POTENTIAL **withrawal can cause rebound anxiety, insomnia, agitation, irritability, and seizures Beta Blockers propanolol **used for palpitations & tremors Other Agents hydroxyzine antihistamine dry mouth, drowsy kava kava herbal over the counter - not regulated by FCNS, ab discomfort...
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This note was uploaded on 04/07/2008 for the course PHARM 338 taught by Professor Karboski during the Fall '07 term at University of Texas at Austin.
- Fall '07