Oncology - Oncology treatment decisions: cell type, TNM...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
Oncology treatment decisions: cell type, TNM Stage, grade, physiological status, performance status, client's goals/choice MOA Examples Toxicities Antimetabolites resemble natural metabolites methotrexate, fluorouracil hematopoietic, GI thioguanine Plant alkaloids arrest/stop mitosis vincristine, etoposide, paclitaxel reproductive, hypersensitivity reactions Topoisomerae I Inhib inhibit topoisomerase enzyme topotecan, irinotecam hematopoietic, GI (camptothecins) S phase MOA Examples Toxicities Antitumor antibiotics doxorubicin, bleomycin hematopoietic, GI, reproductive, cardiac Alkylators cisplatin - platinum hematopoietic, GI, reproductive interfere with DNA replication cyclophosphamide, dacarbazine -- non platinum Nitrosureas carmustine hematopoietic, GI ***CAN CROSS BLOOD-BRAIN CARRIER Hormonal agents interfere w/ hormone receptors dexamethasone, diethylstilbestrol endocrine, reproductive and proteins
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 2

Oncology - Oncology treatment decisions: cell type, TNM...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online