Class Lecture-Control of Ventilation

Class Lecture-Control of Ventilation - Control of...

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Control of Ventilation
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The ventilatory control mechanism must accomplish two tasks. First, it must establish the automatic rhythm for contraction of the respiratory muscles. Second, it must adjust this rhythm to accommodate changing metabolic demands (as reflected by changes in blood PO 2 , PCO 2 , and pH), varying mechanical conditions (e.g., changing posture), and a range of episodic, nonventilatory behaviors (e.g., speaking, sniffing, eating).
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Neurons within the medulla generate signals that are distributed appropriately to various pools of cranial and spinal motor neurons which directly innervate the respiratory muscles
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Automatic Centers in the Brainstem Activate the Respiratory Muscles Rhythmically and Subconsciously The rhythmic output of the central nervous system (CNS) to muscles of ventilation normally occurs automatically, without any conscious effort
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The most important respiratory motor neurons are those that send axons through the phrenic nerve to innervate the diaphragm When respiratory output increases (e.g., during
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