106L03_Notes - CBNS 106 Fall 06 Neuroscience 106: Lecture 3...

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CBNS 106 – Fall 06 106L03_Notes.doc Page 1 of 3 Neuroscience 106: Lecture 3 – Resting Membrane Potential ASSIGNMENTS: In Bear et al study chapter 3. LECTURE: The Resting Membrane Potential (RMP) I. The Resting Membrane Potential (RMP) A. The RMP is typically given as ~ -65 millivolts (mV). However, different classes of neurons have characteristically different RMPs (-65 mV is an average and a convenient number to use). B. The RMP provides a baseline against which signals are produced (like the null state). The figure below shows the effects on RMP of injecting positive or negative ions into a neuron. The voltage across the membrane always reflects the difference between the net – and + charges inside the neuron compared to the net – and + charges outside the neuron. However, a small flux of ions can produce large changes in membrane potential and major changes in membrane voltage can be produced with trivial changes in the concentration of ions. As used in neuroscience Depolarization means – the membrane voltage becomes more positive. As used in neuroscience
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This note was uploaded on 04/15/2008 for the course CBNS 106 taught by Professor Korzus during the Winter '08 term at UC Riverside.

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106L03_Notes - CBNS 106 Fall 06 Neuroscience 106: Lecture 3...

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