april 3 notes

april 3 notes - Bio notes 112 April 3, 2008 Points:...

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Bio notes 112 April 3, 2008 Points: Endocrine system -hormone function -Hypothalamus-pituitary axis -stress response -reproductive hormones Reproduction -mammalian anatomy -gamete production -hormonal regulation -comparative reproduction hormones are chem. Messengers -water soluble (primary proteins) vs. lipid soluble (primary steroids) impact on how hormone works *cell needs to have a receptor to have an effect on the cell Water solube hormone receptor will be on the cell membrane (in the lipid bilayer) -then trgiggers some reaction in the cell the reactions 1. Cascade make a cytoplasmic response, changing the rate of cellular processes 2. One products of the reaction and have an influence on what genes will be transcribed/translated
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Fat soluble hormones -need for a receptor for the steroid to work -lipid can pass through the lipid bilayer -intracellualr receptor the complex will bind to dna and have a effect on what is being transcribed Both require: -receptor Response= hormone + receptor Mechanisms of hormonal signaling: a review. (a) A water–soluble hormone binds to a receptor protein on the surface of a target cell. This interaction triggers a signal transduction pathway that leads to a change in a cytoplasmic function or a change in gene transcription in the nucleus. (b) A lipid–soluble hormone penetrates the target cell s plasma membrane and binds to an intracellular receptor, either in the cytoplasm or in the nucleus (shown here). The signal–receptor complex acts as a transcription factor, typically activating gene expression.
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A particular hormone may cause diverse responses in target cells with different receptors for the hormone, different signal transduction pathways, and/or different proteins for carrying out the response. Consider the multiple effects of epinephrine in mediating the body s response to short–term stress (Figure 45.4). For example, liver cells and the smooth muscle of blood vessels supplying skeletal muscle contain β–type epinephrine receptors,
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april 3 notes - Bio notes 112 April 3, 2008 Points:...

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