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Unformatted text preview: (proteins), determine their three-dimensional conformation. Topics in this course include sequence determinants of secondary structure, the folding of newly synthesized polypeptide chains within cells, folding intermediates aggregation and competing off-pathway reactions, and the unfolding and refolding of proteins in vitro. Additional topics covered are the role of helper proteins such as chaperonins and isomerases, protein recovery problems in the biotechnology industry, and diseases found associated with protein folding defects. *Some translations represent previous versions of courses....
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This note was uploaded on 02/21/2008 for the course BIOL 7.88 taught by Professor Gossard during the Fall '03 term at MIT.
- Fall '03