Chapter 2 - Copyright, 2004, CNS Productions, Inc. 1...

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Unformatted text preview: Copyright, 2004, CNS Productions, Inc. 1 Inhaling Injecting Snorting Orally Transdermal Copyright, 2004, CNS Productions, Inc. 2 Inhaling: 7 to 10 seconds Copyright, 2004, CNS Productions, Inc. 3 Intravenous (IV) Intramuscular (IM) Subcutaneous 15 30 seconds 3 5 minutes 3 5 minutes 4 Copyright, 2004, CNS Productions, Inc. Snorting or Mucosal Exposure: 3 to 5 minutes Copyright, 2004, CNS Productions, Inc. 5 Oral use (ingesting): 20 to 30 minutes Copyright, 2004, CNS Productions, Inc. 6 Contact or Transdermal: 1 to 2 days Copyright, 2004, CNS Productions, Inc. 7 Copyright, 2004, CNS Productions, Inc. 8 Blood-Brain Barrier Copyright, 2004, CNS Productions, Inc. 9 Central Somatic Autonomic 10 Copyright, 2004, CNS Productions, Inc. Evolution of the New Brain Copyright, 2004, CNS Productions, Inc. 11 Reward System of the Brain Copyright, 2004, CNS Productions, Inc. 12 Purkinje cell of the cerebellum Copyright, 2004, CNS Productions, Inc. Pyramidal cell 13 Copyright, 2004, CNS Productions, Inc. 14 Message Arrives Copyright, 2004, CNS Productions, Inc. 15 Message Transmitted Copyright, 2004, CNS Productions, Inc. 16 Cocaine Forces Neurotransmitter Release Copyright, 2004, CNS Productions, Inc. 17 Heroin Inhibits Substance "P" Pain Message Copyright, 2004, CNS Productions, Inc. 18 The Synapse Copyright, 2004, CNS Productions, Inc. 19 Neurotransmitters Acetylcholine Norepinephrine Epinephrine Dopamine Endorphin Enkephalin Serotonin GABA Substance "P" Anandamide Glycine Histamine Nitric oxide Glutamic acid Cortisone 20 Copyright, 2004, CNS Productions, Inc. Development of Amphetamine Tolerance Over Time Desired effect Copyright, 2004, CNS Productions, Inc. 21 Kinds of Tolerance Dispositional Pharmacodynamic Behavioral Reverse Acute Select Inverse (kindling) Copyright, 2004, CNS Productions, Inc. 22 Kinds of Withdrawal Nonpurposive (objective physical signs) Purposive (addict exaggerates symptoms) Protracted (sensory stimuli trigger withdrawal memories) Copyright, 2004, CNS Productions, Inc. 23 The Liver Copyright, 2004, CNS Productions, Inc. 24 Levels of Use Abstention Experimental Social/Recreational Habitual Abuse Addiction Copyright, 2004, CNS Productions, Inc. 25 Addiction Practices addiction most of the time Continues use despite adverse consequences Denies there's a problem After withdrawal has a strong tendency to relapse Has lost control Has altered brain chemistry Copyright, 2004, CNS Productions, Inc. 26 Normal Brain Copyright, 2004, CNS Productions, Inc. Methamphetamine Abuse 27 Chronic Alcohol Abuse Heroin Abuse 28 Copyright, 2004, CNS Productions, Inc. Hereditary Hater of Alcohol Hereditary Lover of Alcohol Alcoholic Mouse Copyright, 2004, CNS Productions, Inc. 29 Hereditary Hater of Alcohol Hereditary Lover of Alcohol Alcoholic Mouse a b c d Copyright, 2004, CNS Productions, Inc. 30 Heredity Levels of Use Addiction Abuse Habituation Social/recreatio nal Experimentatio n Abstinence Levels of susceptibility Susceptibility Copyright, 2004, CNS Productions, Inc. 31 Heredity + Environment Levels of Use Addiction Abuse Habituation Social/recreatio nal Experimentatio n Levels of susceptibility Abstinence Susceptibility Copyright, 2004, CNS Productions, Inc. 32 Heredity + Environment + Drug Use Levels of Use Addiction Abuse Habituation Social/recreatio nal Experimentatio n Levels of susceptibility Abstinence Susceptibility Copyright, 2004, CNS Productions, Inc. 33 Long-Term Heavy Drug Use Levels of Use Addiction Abuse Habituation Social/recreatio nal Experimentatio n Abstinence Levels of susceptibility Susceptibility Copyright, 2004, CNS Productions, Inc. 34 Detoxification & Abstinence Levels of Use Addiction Abuse Habituation Social/recreatio nal Experimentatio n Levels of susceptibility Abstinence Susceptibility Copyright, 2004, CNS Productions, Inc. 35 Relapse Levels of Use Addiction Abuse Habituation Social/recreatio nal Experimentatio n Levels of susceptibility Abstinence Susceptibility Copyright, 2004, CNS Productions, Inc. 36 ...
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This note was uploaded on 04/13/2008 for the course BIO 1033 taught by Professor Joel.martinez,jr.,ph.d. during the Fall '04 term at The University of Texas at San Antonio- San Antonio.

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