6 - Kuo, 580.221 21 Sept 2004 Concepts/Vocabulary Molecules...

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Kuo, 580.221 21 Sept 2004 1 BME 580.221 Nucleic Acids Lecture #06, 21 Sep 2004 Scot C. Kuo 21 Sept 2004 Kuo, 580.221 Concepts/Vocabulary • Structure = Function; amino acid sequence determines structure • Specificity of base-pairing: same weak forces as in protein structure • Review: structure of RNA & DNA; replication of DNA 21 Sept 2004 Kuo, 580.221 Structure of Nucleic Acids Sugar backbone 21 Sept 2004 Kuo, 580.221 Structure of Nucleic Acids Principal Bases 21 Sept 2004 Kuo, 580.221 Naming Nucleo s ides (lack s phosphate) and Nucleo t ides (nucleoside with 5’ phospha t es) add cartoon from Lehninger? 21 Sept 2004 Kuo, 580.221 Nucleic Acid Chains
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Kuo, 580.221 21 Sept 2004 2 21 Sept 2004 Kuo, 580.221 DNA double helix Strands are antiparallel 21 Sept 2004 Kuo, 580.221 21 Sept 2004 Kuo, 580.221 DNA double helix detail 21 Sept 2004 Kuo, 580.221 Show QTV of nucleic acid struct 21 Sept 2004 Kuo, 580.221 Models of DNA helices 21 Sept 2004 Kuo, 580.221 Protein binding can deform DNA
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Kuo, 580.221 21 Sept 2004 3 21 Sept 2004 Kuo, 580.221 Central Dogma of Molecular Biology • DNA->RNA->protein • All cells, from bacteria to
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This note was uploaded on 04/15/2008 for the course BME 580.221 taught by Professor Dr.vidal during the Fall '08 term at Johns Hopkins.

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6 - Kuo, 580.221 21 Sept 2004 Concepts/Vocabulary Molecules...

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