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study guide exam II chap 8 and 9

study guide exam II chap 8 and 9 - Study_guide_exam_II...

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Study_guide_exam_II- chapters 8 and 9 Chapter 8 Start from p246 - Finishing Replication 1. What is the major “problem” encountered by circular DNA when it finishes replication? How is this resolved? 2. For Linear DNA replication, what is meant by the phrase “extreme end problems”? Which strand does this apply to? 3. There are multiple solutions to the end replication problem. We talked about two of them, what are they? 4. Explain Protein priming. What organisms is this found in? 5. What is the function of telomeres. What is the function of telomerase? Is it a DNA polymerase? Does telomerase require an exogenous primer? Why or why not. Define TER and TERT. 6. Explain how the elongation of the 3’ end by telomerase solves the shortening of chromosomes. 7. Briefly, how do some telomere binding proteins regulate the length of telomeres. 8. Chromosomes normally have a 3’ single-stranded region at their ends, but this ssDNA is protected from degradation.
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