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q10 - Unipotent Differentiated tissues(i.e sperm in males...

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CH388 AY08-01 Cadet __________________ Quiz #10 (50 points) Section _____ You have 10 minutes to complete this quiz, pencil only. No references are authorized. 1. (10 pts) Turn-in of Micro Symposium Summary 2. (15 pts) Describe the difference(s) between pluripotency, multipotent, totipotent, & unipotent stem cells AND when they occur in the human development. Some stem cells have more capabilities (potency) Unipotent- can form only one type of cell Multipotent- form multiple different cell & tissue types Pluripotent- form most or all of the 210 differentiated cell types in adults Totipotent- form all adult body cell types and specialized tissues for embryo development (i.e., placenta) Totipotent Embryonic stem cells (ES) Pluripotent Embryonic germ cells (EG), Fetal Tissue stem cells, Cord/placental stem cells, and some “adult” stem cells, Embryonal carcinoma cells (EC) Multipotent Fetal Tissue stem cells, Cord/placental stem cells, and some “adult” stem cells
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Unformatted text preview: Unipotent Differentiated tissues (i.e., sperm in males) 3. (5 pts) List one disease that gene therapy has the potential to treat. Alzheimers, Parkinson’s, Huntington’s, heart disease, (Table 19.6 lists several) 4. (10 pts) Explain the relationship between penetrance of a gene mutation and the clinical presentation of symptoms for a disease phenotype. A genetic mutation must have an effect such that it disrupts the normal cellular machinery or gene function to result in a diseased phenotype. Thus, the gene must penetrate the normal functioning levels to observe a clinical effect. 5. (10 pts) Match the following terms: e ___ homeotic gene a. final morphological features that a cell will adopt c ___ apoptosis b. gene that is expressed after fertilization a ___ cell fate c. programmed cell death b ___ zygotic gene d. homologous genes in different species d ___ orthologs e. gene that functions in governing the fate of a particular body region...
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