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6_Mutation - Mutation Basics on A mutation is a heritable...

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Mutation Basics on 2/20/07 A mutation  is a heritable change in the genetic material (the gene, not DNA because it could be  RNA) - a change in RNA can’t be passed on though - there are no cells that use anything other than DNA as their genetic material > but some viruses use RNA as their genetic material - “ a heritable change ” is when the parent cells pass it on to the daughter cell > if the UV rays change your skin, it IS genetic on a CELLULAR  sense > only what is “copably” in DNA polymerase Point mutations from the DNA perspective point mutation  – is a small mutation that effects a small area it effects ONE  nucleotide, or just ONE  base pair o the base-pair is changed at  replication  because the complementary strand will  become complimentary to THAT change. Types: o SUBSTITUTION      – the number of nucleotides have NOT change, but the  identity of one nucleotide or base pair HAS changed. It may be a “ TRANSITION ”:  which will cause a Y   different Y (pyrimidine) or cause a R   different R (purine) it may be a “ TRANSVERSION  R Or R   Y Deletion - a LOSS of one or more nucleotides, which will also become a loss of a base pair the nucleotide/base pair is COMPLETE taken out, missing! o CCTACC deletion CCACC the T is gone!, but there’s no space for it, so you don’t know if something got deleted unless you know what its SUPPOSE to be.
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