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Unformatted text preview: Mutation Basics on 2/20/07 A mutation is a heritable change in the genetic material (the gene, not DNA because it could be RNA)- a change in RNA cant be passed on though- there are no cells that use anything other than DNA as their genetic material > but some viruses use RNA as their genetic material- a heritable change is when the parent cells pass it on to the daughter cell > if the UV rays change your skin, it IS genetic on a CELLULAR sense > only what is copably in DNA polymerase Point mutations from the DNA perspective point mutation is a small mutation that effects a small area it effects ONE nucleotide, or just ONE base pair o the base-pair is changed at replication because the complementary strand will become complimentary to THAT change. Types: o SUBSTITUTION the number of nucleotides have NOT change, but the identity of one nucleotide or base pair HAS changed. It may be a TRANSITION : which will cause a Y different Y (pyrimidine) or cause a R different R (purine) it may be a TRANSVERSION Y R Or R Y Deletion- a LOSS of one or more nucleotides, which will also become a loss of a base pair the nucleotide/base pair is COMPLETE taken out, missing!...
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