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MCB 3208 CHAPTER 9 AUTONOMIC NERVOUS SYSTEM Overview of autonomic nervous system control Cardiovascular, respiratory, gastrointestinal, renal and some aspects of eye function designed so they can increase or decrease output as necessary (e.g, exercise and fight or flight). This involves alterations of smooth muscle and heart and various epithelial and gland structures, including changes in heart rate and strength of contraction as well as in constriction and dilation of arterioles. These are all regulated without our thinking about it, i.e., subconscious. DIVISIONS OF THE NERVOUS SYSTEM Afferent or Sensory From sense organs to brain, both conscious and unconscious sensations. These include the obvious sensations and also those that are unconscious, like the sensors that detect blood pressure Efferent Somatic: motor nerves to muscles, single nerve and muscle and one synapse. These release acetylcholine and act on a nicotinic ACh receptor. Single function is to stimulate muscle to contract. Autonomic: nerves to smooth muscle, heart muscle, glands; differences from somatic nerves: (i) Sympathetic and paraympathetic divisions with distinct functions (ii) two neurons before synapse with effector (iii) multiple neurotransmitters and receptors (iv) either stimulation or inhibition of effector (v) anatomy: nerve 1, synapse in ganglion, nerve 2, synapse on effector The neuromuscular junctional synapse is very well developed and specialized. In contrast, release sites
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This note was uploaded on 01/23/2009 for the course MCB 57703 taught by Professor Machen during the Fall '08 term at University of California, Berkeley.

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