bis_104_endomembr_syst_08

bis_104_endomembr_syst_08 - Calcium storage Golgi complex...

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ENDOMEMBRANE SYSTEM What is the endomembrane system? An intra-cellular membrane system that sub-divides the cytoplasm into functional and structural components. What are the main components? Endoplasmic reticulum (“network within the cell”) ER Rough endoplasmic reticulum (RER) Ribosomes bound to cytosolic side Biosysnthesis and processing of proteins Some glycosylation Assembly of multimeric proteins Correction of mis-folded proteins ER – associated degradation (ERAD) Smooth endoplasmic reticulum (SER)
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Steroid synthesis Phospholipid synthesis Drug detoxification (cytochrome p-450 family) Breakdown of stored glycogen
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Unformatted text preview: Calcium storage Golgi complex Cis-Golgi network (CGN) Med - Golgi network (MGN) Trans- Golgi network (TGN) Processing, packaging, transport of proteins Endosomes: vesicles budded off from PM Lysosomes : vesicles containing hydrolytic enzymes Transport vesicles : cargo + lipid wrapper Anterograde: movement away from center of cell Retrograde: movement toward center of cell Direction: Cytoskeleton Microtubules Microfilaments Translocating power motor proteins Kinesins Dyneins Transport and secretory pathways (Karp, Fig. 8.2) Regulated pathway Constitutive pathway...
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This note was uploaded on 01/24/2009 for the course BIS 104 taught by Professor Scholey during the Fall '08 term at UC Davis.

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bis_104_endomembr_syst_08 - Calcium storage Golgi complex...

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