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Patho. Micro. Test IV II

Patho. Micro. Test IV II - Lab Diagnosis of Viral Diseases...

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Lab Diagnosis of Viral Diseases Viruses, virions, and prions are acellular infectious agents A virus is a gentic element with either RNA or DNA, but not both They have a requirement to replicate inside a living cell Has an extracellular state called a virion Mimivirus Contains both DNA and RNA World’s largest virus Infects protozoa and humans, but causes mild pneumonia in humans Extracellular state Inert, or can’t move Consists of a nucleic acid genome in a protein coat called a capsid or a membrane called an envelope Intracellular State Smaller than cells, measured in micrometers, about .2-.3 Capsid Made of protein subunits, which associate into capsomeres and then into the capsid Capsid or nucleic acid-binding proteins may associate with the genome to form a nucleocapsid Envelope Membrane composed of lipids and proteins Can be maintained only in aqueous solution and is disrupted by drying and detergents, so viruses with an envelope must remain wet
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Patho. Micro. Test IV II - Lab Diagnosis of Viral Diseases...

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