LeukeOutline - The Genetic Code 1 Know how it was...

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The Genetic Code 1. Know how it was determined that the code was read in consecutive triplets. 2. Be able to describe the experiments that led to the elucidation of the code. tRNA 1. Be able to draw and label a tRNA molecule. Understand the mechanism for charging a tRNA as well as how the aminoacyl tRNA synthetases proof read their reaction. 2. Know what wobble is and its consequences. What are the dangers of wobble? Why are there only about 50 tRNA’s to read 61 codons. Why do many organisms have less than 50 tRNA genes? Ribosomes 1. Know the function of free versus bound ribosomes. What is a polysome and are they free or bound? 2. Know the composition of the ribosomes (prokaryote versus eukaryote). 3. Know the relative stability of the RNA’s. Translation 1. How was the direction of protein synthesis determined? Dintzi’s experiment. 2. Be able to briefly describe or diagram each step of translation (initiation, elongation and termination). 3.
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LeukeOutline - The Genetic Code 1 Know how it was...

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