This preview has intentionally blurred sections. Sign up to view the full version.View Full Document
Unformatted text preview: germ-line mutation somatic mutation loss-of-function mutation hypomorphic mutation hypermorphic mutation gain-of-function mutation silent substitutions missense mutations nonsense mutations frameshift mutations transposable elements thymine dimmer UV irradiation gamma irradiation transition transversion Mismatch repair mechanism Uracil DNA glycosylase mech. Nucleotide excision repair mech. Ames test cancer two-hit hypothesis loss of heterozygosity gel electrophoresis Southern blot probe hybridize probe Oncogene/proto-oncogene Tumor suppressor gene Apoptosis metastasis/metastasize Hardy-Weinberg equilibrium Population Sub-population gene pool genotype frequency allele frequency inbreeding natural selection evolution fitness genetic drift maternal inheritance multifactorial traits/quantitative traits continuous traits meristic traits threshold traits distribution for a trait variance Broad-sense heritability QTL...
View Full Document
This note was uploaded on 04/15/2008 for the course BIO SCI 98 taught by Professor Goulding during the Spring '08 term at UC Irvine.
- Spring '08