Introduction to Neurobiology - Lecture Notes 04 - Action Potential & Propagation I

Introduction to Neurobiology - Lecture Notes 04 - Action Potential & Propagation I

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BioNB222 Spring 2008 Cornell University Joseph Fetcho 1 Lecture 4. Action Potentials and Propagation I Lecture Outline 1. Why action potentials? We saw earlier that recordings from neurons reveal very large, stereotypic events called action potentials. If we record from an axon of a motoneuron at different locations along the axon’s path out to muscle we would see action potentials at each location, with some delay as we move farther along the axon. Action potentials are important because passive properties of neurons lead to the decay of the changes in membrane potential over long distances. In order to have electrical changes in the cell body of a motoneuron in the spinal cord transmitted out to the muscle, the signal needs to be amplified or regenerated along the way, much like the boosting of radio or cell phone transmission. Action potentials do this. We will explore how… the answer led to a Nobel prize.
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  • Spring '08
  • Hopkins
  • Neurobiology, Action Potentials, Cornell University, Joseph Fetcho

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