BrookerChp8_ChromosomeVariation - A Euploidy[Fig 8.16 1...

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Chapter 8 – Chromosomal Variations I. Individual chromosome structure (chromosome mutation/chromosomal aberration) A. Review common nomenclature [Fig. 8.1] B. Altered structures result in altered gene placement/regulation [Fig. 8.2] 1. Deletion (gene loss may affect viability/phenotype) [Fig. 8.4] 2. Duplication; evolution of gene families [Figs. 8.9, 8.10] 3. Inversion (pericentric vs. paracentric) [Figs. 8.11, 8.12] 4. Translocation (balanced vs. unbalanced) [Fig. 8.13] II. Variation in chromosomal number (genome-level mutation)
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Unformatted text preview: A. Euploidy [Fig. 8.16] 1. Diploid (2N) 2. Polypoid (3N, 4N, etc) 3. Plants more commonly tolerate euploidy (autopolyploidy, alloploidy, allopolyploidy) [Fig. 8.27] B. Aneuploidy [Fig. 8.16, 8.17] 1. Monosomy (2N – 1) 2. Trisomy (2N + 1) 3. Aneuploidy in humans [Table 8.1] C. Nondisjunction in meiosis [Fig. 8.24] D. Nondisjunction in mitosis [Fig. 8.25] III. Study Suggestions A. Solved Problems: S1 – S4 B. Conceptual Questions: C1, C2, C6 – C9, C11, C14, C17 – C20, C22, C25, C31, C32, C39, C41...
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This note was uploaded on 04/16/2008 for the course BIO 325 taught by Professor Saxena during the Spring '08 term at University of Texas.

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