JV3 KEY - BIBC 102 Metabolic Biochem Handout #3 1/30/08 TA:...

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BIBC 102 – Metabolic Biochem                                 TA: Jacqueline Vu  (jacquelinevu.j@gmail.com) Handout #3 1/30/08                                                       OH:  Weds @12:10-1:10pm in Café  Roma  Glycolysis I. Glycolysis  a. Know how to draw structures b. G     oodness  G racious  F ather  F ranklin  D id  G B P icking  P umpkins (to)  P repare  P ies (11) c. Enzymes:  H ungry  P eter  P an  A nd  T he  G rowling  P ink  P anther  E at  P ies (10) II. Schiff Base Formation a. Occurs in step 4 of Glycolysis b. Only a C-C breaking c. The structures can be seen in the book.  Look up Schiff base, this occurs is step 4 of  glycolysis 1
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TA: Jacqueline Vu  (jacquelinevu.j@gmail.com) Handout #3 1/30/08                                                       OH:  Weds @12:10-1:10pm in Café  Roma d. What is the role of a Schiff base? a. Stabilizes intermediates III. Substrate Channelling  a. Explain s.c. and why is it important? a. The product of the 1 st  enzyme is directly shuttled to the 2 nd  enzyme to  avoid loss of free energy, hydrolysis and speeds the reaction b. Show two reactions and the enzymes using substrate channelling in the glycolysis  pathway IV. Substrate Level Phosphorylation a. What is substrate phosphorylation? a. Inorganic phosphate is added to acyl-P (formation of a MIXED  ANHYDRYDE)  V. Anaerobic conditions: Pyruvate Undergoes Fermentation a. In muscles:      Pyruvate is reduced to  lactate . An important reason why this reaction  occurs is because cofactor,  NAD+,  is reregenerated from  NADH . a. Write structural formula and specific enzymes equation is of pyruvate   lactate b.     Pyruvate is concerted to ethanol and CO2. a.
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This note was uploaded on 04/15/2008 for the course BIBC 102 taught by Professor Price during the Winter '02 term at UCSD.

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JV3 KEY - BIBC 102 Metabolic Biochem Handout #3 1/30/08 TA:...

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