JV5 KEY - Jacqueline Vu Worksheet #5 The Citric Acid Cycle...

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Jacqueline Vu Worksheet #5 The Citric Acid Cycle (Kreb Cycle: The Hub of Metabolism) 1. TCA Cycle:  Draw the cycle and include all enzymes and structural formula for the  intermediates.   Keep track of where C from acetyl-CoA go in TCA cyle.  Know all structures and  enzymes! 2. Labeling Acetyl-CoA with  14 C: a. After the first cycle, are we able to obtain labeled  14 CO 2 ? NO, Both come from CO 2  oxaloacetate 1
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Jacqueline Vu Worksheet #5 b. From the second cycle, are we able to obtain labeled  14 CO 2 ? YES, because left over carbons from acetyl-CoA became oxaloacetate in second  cycle. 3. The reaction most similar to the pyruvate dehydrogenase reaction is the conversion of  - α Ketogluterate  to  succinyl Co-A . 4. The reaction which produces an ATP equivalent (GTP) by phosphorylation is the conversion of  succynl-CoA  to  succinate . 5. Which is the redox reaction not involving NAD+/NADH? a. What is special about the enzyme catalyzing the reaction? ****** only enzyme that is MEMBRANE BOUND******* 6. What are the key allosteric enzymes in this cycle?
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This note was uploaded on 04/15/2008 for the course BIBC 102 taught by Professor Price during the Winter '02 term at UCSD.

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JV5 KEY - Jacqueline Vu Worksheet #5 The Citric Acid Cycle...

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