Book note1 - Macronutrients: C, H, O, N, P, S, K, Mg, Ca,...
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Macronutrients: C, H, O, N, P, S, K, Mg, Ca, and Fe
Fe3+ is transported into cells as a chelate
(binding of a ligand (( a molecule that bonds to a central metal and transfers
electrons, in this case Iron)))
Hydroxamates (most common sideophore)
Mostly in insoluble minerals in the +3 oxidation state (ferric acid)
To obtain oxygen cells produce
siderophores (compounds that bind Fe3+ to
chelates) that bind to
iron and transport it into the cell.
Iron is then transpoted as chelate into cells
Iron in the Fe2+ state and soluble
Notes: Hyrdroxymate. Iron is bound as Fe3+ and released inside the cell as Fe2+. The hydroxymate then exits the cell and
repeats the cycle.
coliform bacterian (Escherichia, Salmonella, Shigella), produce very powerful phenolic sideophores
which are derivatives of
Siderophores called enterobactins
Very important in pathogencicity because idon is often scarce in animal tissue.
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Can be virtually undetectable.
Siderophores called AQUACHELINS
They have a peptide head and hydrophobic tail to interact with membrane.
Some organisms, such as
(Lyme disease pathogen), can grow in
the total absence of iron. In these organisms, Mn2+ substitutes for iron as the metal component of enzymes that normally
Typically but not always are metals that are critical to cell function but are requires only in tiny amounts
A.K.A Trace Elements
Most commonly play role in catalaysis as components of some enzyme.
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This note was uploaded on 04/15/2008 for the course HIST 101 taught by Professor Smith during the Spring '08 term at Michigan State University.