hemoglobin_study_guide

hemoglobin_study_guide - Hemoglobin Study Guide This study...

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Hemoglobin Study Guide This study guide is NOT meant to be comprehensive. That means that it covers some of the more complicated aspects of gas exchange in mammals BUT NOT ALL ASPECTS. You are responsible for ALL of the material previously assigned in the book and gone over in lecture, whether it is described herein or not. This review is meant to help you understand some of the more complicated aspects. 1) The T and R states are structural descriptions of hemoglobin. The two states are always in equilibrium with one another (T R). Some particular solution conditions will push the equilibrium to one state while different conditions will favor the other. 2) The deoxy and oxy forms of hemoglobin are chemical descriptions and, although there is a correlation between the deoxy/oxy forms and the T/R states, you should consider them as very separate and unique. Although the R state has a higher affinity for oxygen, both states (T or R) can exist in the oxygenated form or the deoxygenated form. If this seems confusing read the remainder of this study guide and if you are still struggling see Professor Love in office hours. 3) The transition between the T and R states is considered to be binary; that is, hemoglobin exists in either the T or R state and there are no stable intermediates. Remember the image of the knobs fitting into the holes. An intermediate would put a knob on a knob
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hemoglobin_study_guide - Hemoglobin Study Guide This study...

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